Transcriptome assemblies for two drug-type cannabis chemotypes by long-read RNA sequencing. [PDF]
Berkowitz O +5 more
europepmc +1 more source
Abstract Objective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and ...
Thomas Harman +5 more
wiley +1 more source
Cannabidiol and ∆9-Tetrahydrocannabinol in Endometriosis: A Literature Review on Therapeutic Applications and Mechanisms. [PDF]
Godoy JR +3 more
europepmc +1 more source
Rapid LC-QTOF-MS screening method for semi-synthetic cannabinoids in whole blood. [PDF]
Schirmer W +5 more
europepmc +1 more source
The Relationship Between (Endo)cannabinoids, the Microbiome and Melanoma
CB1 and CB2 receptors are widely distributed in both normal and cancerous cells. Cannabinoids have a positive impact on reducing tumor growth in mice. A positive relationship exists between CB2 receptors and survival in skin melanoma. However, there is a negative impact on non‐small cell lung cancer and colon cancer, whereas a higher association of CB1
Farideh A. Javid +3 more
wiley +1 more source
Suicide attempt and paranoia persisting for 28 days following heavy delta-9-tetrahydrocannabinolic acid and tetrahydrocannabinol use: A case report. [PDF]
Greer D, Dey P, Kulig CE.
europepmc +1 more source
Abstract Aim To monitor community‐level consumption of 20 illicit drugs across urban areas of England using wastewater‐based epidemiology (WBE) surveillance at high temporal resolution. Design, setting, cases This study was conducted over a 12‐month period in 2022 sampling 24‐hour composite wastewater samples at 15 wastewater treatment plants (WWTPs ...
Helena Rapp‐Wright +14 more
wiley +1 more source
In Vitro Antimicrobial Effect of Tetrahydrocannabinol on Streptococcus mutans and Its Anticariogenic Potential. [PDF]
Zhai H +7 more
europepmc +1 more source
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli +8 more
wiley +1 more source
CARE - A Retrospective, Dual-Cohort, 24-Week Real-World Study from the German Pain e-Registry on the Effectiveness and Safety of CBD-Dominant Oral Cannabis Extracts versus THC/Dronabinol in Older Patients with Chronic Pain. [PDF]
Überall MA +3 more
europepmc +1 more source

