Results 181 to 190 of about 20,935 (240)
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Tetrahydrocannabinol and acetylcholinesterase
Pharmacology Biochemistry and Behavior, 1978Recent evidence suggests that the psychoactive effect of delta-9-tetrahydrocannabinol (delta9-THC), the major psychoactive constituent of marihuana, may be mediated through an alteration of cholinergic neurotransmission. One possible mechanism by which delta9-THC could have its effect is by affecting acetylcholinesterase (AChE) and there is evidence ...
D E, Moss, P L, Peck, R, Salome
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Tetrahydrocannabinol and Cannabidiol in Tourette Syndrome
NEJM Evidence, 2023BACKGROUND: Tourette syndrome is characterized by chronic motor and vocal tics. There is preliminary evidence of benefit from cannabis products containing Δ9-tetrahydrocannabinol (THC) and that coadministration of cannabidiol (CBD) improves the side-effect profile and safety.
Mosley, Philip E. +13 more
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Stability of Tetrahydrocannabinols II
Journal of Pharmaceutical Sciences, 1978The biphasic degradation of delta9-tetrahydrocannabinol (I), as monitored by flame-ionization GLC, produced delta8-tetrahydrocannabinol (II), cannabidiol (X), 9-hydroxyhexahydrocannabinol (VI), 9,10-dihydro-9-hydroxyisocannabidiol (VI), and and 6,12-dihydro-6-hydroxycannabidiol (VIII) in acidic solutions.
E R, Garrett, A J, Gouyette, H, Roseboom
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Synthetic Tetrahydrocannabinol
Journal of Forensic Sciences, 1983Abstract This paper presents the synthetic route used and the identification of the precursors and reaction products in a clandestine laboratory manufacture of cannabidiol (CBD), μ9-cis-tetrahydrocannabinol (μ9)-cis-THC), and μ9-trans-tetrahydrocannabinol (μ9-trans-THC).
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Stability of Tetrahydrocannabinols I
Journal of Pharmaceutical Sciences, 1974Δ9-Tetrahydrocannabinol, as monitored by flame-ionization GLC at various temperatures, degrades by a biphasic semilogarithmic curve with time in acidic aqueous solutions (
E R, Garrett, J, Tsau
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The Metabolism of the Tetrahydrocannabinols
1972Publisher Summary Because of the long history of Cannabis usage in man, Δ 9 -tetrahydrocannabinols (THC) is unique in that its pharmacology has been examined in humans almost simultaneously with the animal studies. Within the past few years, there has been rapid progress in elucidating the pharmacology of this interesting group of compounds ...
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Psychological Effects of Tetrahydrocannabinol
Archives of General Psychiatry, 1970THE MORE widespread use of marihuana and marihuana-like drugs in the general population and the controversy about their possible harmful, as well as beneficial, effects have led to an increased interest in studying these compounds during the last few years.
I E, Waskow +3 more
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A comparison of the disposition of 14C-Δ9-tetrahydrocannabinol and 3H-Δ9-tetrahydrocannabinol
Life Sciences, 1977Abstract Preliminary experiments suggested that total levels of radioactivity disappeared from the blood of male, Fischer rats much more rapidly following intragastric administration of 14 C-Δ 9 -tetrahydrocannabinol ( 14 C-THC) than 3 H-THC. Collaborative experiments at the Stanford Research Institute (SRI) and the Research Institute on Alcoholism
G T, Pryor, S, Husain, A J, Siemens
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