Results 11 to 20 of about 1,973 (233)

Tetrahydrofolate Recognition by the Mitochondrial Folate Transporter [PDF]

Journal of Biological Chemistry, 2011
A mitochondrial carrier family (MCF) of transport proteins facilitates the transfer of charged small molecules across the inner mitochondrial membrane. The human genome has ∼50 genes corresponding to members of this family. All MCF proteins contain three repeats of a characteristic and conserved PX(D/E)XX(K/R) motif thought to be central to the ...
Scott A, Lawrence, John C, Hackett, Richard G, Moran   +2 more
openaire   +4 more sources

Tetrahydrofolat-spezifische Enzyme im Baustoffwechsel von Methanosarcina barkeri sowie die Rolle von Folsäure und p-Aminobenzoesäure als Wachstumsfaktoren in diesem Archaeon [PDF]

, 2004
Tetrahydrofolat (H4F) spielt als Überträger von C1-Einheiten im Baustoffwechsel von allen Bacteria und Eucarya und von einigen Archaea eine wichtige Rolle in der Synthese von C1-Einheiten enthaltenden Verbindungen wie Purine, Thymidin und Methionin.
Buchenau, Bärbel, Thauer, Rudolf K. (Prof. Dr.)   +1 more
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Stimulation by Spermine of Tetrahydrofolate Formylase Activity

Journal of Biological Chemistry, 1964
E M, LANSFORD, R B, TURNER, C J, WEATHERSBEE, W, SHIVE   +3 more
openaire   +3 more sources

Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, intakes of folate and related B vitamins and colorectal cancer : a case-control study in a population with relatively low folate intake [PDF]

, 2007
Peer reviewedPublisher ...
Andreassi, Boreham, Breslow, Chen, Erens, Finch, Guenther, Holland, Hosmer, Jim Cassidy, Julian Little, Kawakami, Keku, Khlat, Kim, Linda Sharp, Lindsey F. Masson, Ma, Ma, Narayanan, Neva E. Haites, Nigel T. Brockton, Parkin, Rozen, Seonaidh C. Cotton, Slattery, White   +26 more
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Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues [PDF]

, 2022
The ability to effectively detect bacterial infection in human tissues is important for the timely treatment of the infection. However, traditional techniques fail to visualize bacterial species adhered to host cells in situ in a target-specific manner ...
Chen, Zhao Hong, Gan, Hui Qi, Gong, Teng, He, Xiao Peng, Hu, Xi Le, James, Tony D., Luo, Peng Fei, Shu, Fu Ting, Wei, Pei, Xia, Zhao Fan, Yan, Kai Cheng, Yang, Xiao Lan, Zheng, Yong Jun, Zhong, Chen Jian   +13 more
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Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population. [PDF]

, 2014
One-carbon metabolism (folate metabolism) is considered important in carcinogenesis because of its involvement in DNA synthesis and biological methylation reactions.
Baecker, Aileen, Butler, Brendan, Cai, Lin, Chang, Po-Yin, Chang, Shen-Chih, Goldstein, Binh Y, Greenland, Sander, Heber, David, Li, Liming, Lu, Qing-Yi, Mu, Lina, You, Nai-Chieh Y, Yu, Shun-Zhang, Zhang, Zuo-Feng   +13 more
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Isolation and Sequencing of a Plant cDNA Encoding a Bifunctional Methylenetetrahydrofolate Dehydrogenase : Methenyltetrahydrofolate Cyclohydrolase Protein

Pteridines, 1999
In plant cells, the interconversion of formyl- and methylene-tetrahydrofolates is catalyzed by a bifunctional protein possessing methenyltetrallydrofolate cydohydrolase (EC 3.5.4.9) and methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5) activities. The
Chen Liangfu, Nargang Frank E., Cossin Edwin A.   +2 more
doaj   +1 more source

Folate polyglutamylation is required for rice seed development [PDF]

, 2010
In plants, polyglutamylated folate forms account for a significant proportion of the total folate pool. Polyglutamylated folate forms are produced by the enzyme folylpolyglutamate synthetase (FPGS).
A Wingler, AD Hanson, AD Hanson, Anahi Santoyo Castelazo, Anne Diévart, B Gambonnet, B Shane, BA Moffatt, BF Lin, BF Lin, CR Somerville, D Heineke, David A. Barrett, Delphine Mieulet, E Cossins, Emmanuel Guiderdoni, G Orsomando, GJ Basset, GJ Basset, GJ Basset, Gregory Tucker, H Bauwe, H Imeson, Helen Parker, I Hayashi, JR Suh, K Gallardo, KR Lowe, L Chen, L DeSouza, LC Garratt, Malcolm J. Bennett, ML Jones, Nadège Lanau, Nampeung Anukul, O Galivan, PA Counce, Payam Mehrshahi, R Díaz de la Garza, Riza Abilgos Ramos, S Jabrin, S Ravanel, S Ravanel, S Storozhenko, V Besson, X Sun, Y Wang   +46 more
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The Dissociation Constants of Tetrahydrofolic Acid

Journal of Biological Chemistry, 1966
Six dissociable groups exist in tetrahydrofolic acid in the range H0 -3.0 to pH 14. The assignments in tetrahydrofolic acid by titrimetric and spectrophotometric comparisons with model compounds, p-aminobenzoylglutamic acid and 2-amino-6,7-dimethyl-5,6,7,8-tetrahydro-4-pteridinone, are as follows: acidic ionization of amide, pK' 10.5; N5, pK' 4.82; γ ...
R G, Kallen, W P, Jencks
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Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia [PDF]

, 2011
Predicting the response to medical therapy and subsequently individualizing the treatment to increase efficacy or reduce toxicity has been a longstanding clinical goal.
Jacob Nersting, Kjeld Schmiegelow, Louise Borst   +2 more
core   +3 more sources