Results 61 to 70 of about 5,203 (175)

(S)-Methyl 2-[(3R,4R)-2-benzyl-3-(2-furyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamido]-3-(1H-indol-3-yl)propanoate

Acta Crystallographica Section E, 2009
The title compound, C33H29N3O5, was synthesized by the reaction of racemic trans-2-benzyl-3-(2-furyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid, l-tryptophan methyl ester and diisopropylcarbodiimide in dry dichloromethane.
Zeliha Baktır, Mehmet Akkurt, Meglena I. Kandinska, Milen G. Bogdanov, Orhan Büyükgüngör   +4 more
doaj   +1 more source

Studies on tetrahydroisoquinolines. XX. A novel synthesis of 8-aryl-1,2,3,4-tetrahydroisoquinolines.

Chemical and Pharmaceutical Bulletin, 1983
Treatment of a mixture of the p-quinol acetate (4) and aryl ethers with trifluoroacetic acid gave 8-aryl-1, 2, 3, 4-tetrahydroisoquinolines (1a-f) in good yields. Similar reaction of 4 and corypalline (3) afforded a corypalline dimer (5).
HARA, HIROSHI, HOSHINO, OSAMU, UMEZAWA, BUNSUKE   +2 more
openaire   +2 more sources

Acid Catalyzed Formation of C–C and C–S Bonds via Excited State Proton Transfer

Molecules, 2019
The behavior of 2-naphthol and 7-bromo-2-naphthol as organic photoacids are exploited in organic synthesis for the preparation of benzyl sulfides (using a trichloroacetimidate derivative as the starting substrate) and polycyclic amines via acid catalyzed
Alessandro Strada, Mattia Fredditori, Giuseppe Zanoni, Stefano Protti   +3 more
doaj   +1 more source

1,2,3,4-Tetrahydroisoquinoline-2-sulfonamide

Acta Crystallographica Section E, 2008
The title compound, C9H12N2O2S, is a useful precursor of a variety of modified sulfonamide molecules. Due to the importance of these molecules in biological systems (antibacterials, antidepressants and many other applications), there is a growing ...
Carole Barbey, Nour-Eddine Aouf, Malika Berredjem, Radia Bouasla   +3 more
doaj   +1 more source

One-pot Ugi-azide and Heck reactions for the synthesis of heterocyclic systems containing tetrazole and 1,2,3,4-tetrahydroisoquinoline

Beilstein Journal of Organic Chemistry
A new method for the synthesis of heterocyclic systems containing tetrazole and tetrahydroisoquinoline is developed via the performance of one-pot Ugi-azide and Heck cyclization reactions.
Jiawei Niu, Yuhui Wang, Shenghu Yan, Yue Zhang, Xiaoming Ma, Qiang Zhang, Wei Zhang   +6 more
doaj   +1 more source

Asymmetric Synthesis of Tetrahydroisoquinoline Alkaloids Using Ellman's Chiral Auxiliary

Natural Product Communications, 2017
Chiral t -butylsulfinamide has been successfully employed for the stereoselective synthesis of 1-benzyl tetrahydroisoquinoline alkaloids. This is the first report on the synthesis of chiral 1-benzyltetrahydroisoquinoline natural products using tert ...
Y. Vikram Reddy, Dhanraj O. Biradar, B. Jagan Mohan Reddy, Aravinda Rathod, M. Himabindu, B. V. Subba Reddya   +5 more
doaj   +1 more source

Synthesis of Some Novel 11b-Substituted Pyrimido[6,1-a]-isoquinoline Derivatives

Molecules, 2004
A series of novel 11b-substituted 1,6,7,11b-tetrahydropyrimido[6,1-a]- isoquinoline-2,4-diones and 4-thioxo-1,3,4,6,7,11b-hexahydropyrimido[6,1-a]isoquinolin-2- ones were synthesized, utilizing two alternative strategies for ring closure of ...
Atanas P. Venkov, Iliyan I. Ivanov, Plamen A. Angelov   +2 more
doaj   +1 more source

(S)-4-tert-Butyl-2-(1,2,3,4-tetrahydroisoquinolin-3-yl)-1,3-thiazole

Acta Crystallographica Section E, 2012
In the title compound, C16H20N2S, a potential tetrahydroisoquinoline (TIQ) thiazole ligand, the N-containing six-membered ring of the TIQ unit adopts a half-chair conformation. There are four molecules in the asymmetric unit.
Sunayna Pawar, Thavendran Govender, Hendrik G. Kruger, Glenn E. M. Maguire   +3 more
doaj   +1 more source

Heterogeneous Catalysts in Pictet-Spengler-Type Reactions

Journal of Chemistry, 2013
Several solid catalysts were evaluated as an alternative for 1,2,3,4-tetrahydroisoquinoline synthesis by means of the Pictet-Spengler reaction. The reaction catalysed by a mixed oxide (Mg and Al) led to the best yield and good regioselectivity; using an ...
Rodolfo Quevedo, Camilo Perdomo, Sonia Moreno   +2 more
doaj   +1 more source

2-Phenylquinolines Exhibit Anti-Severe Acute Respiratory Syndrome Coronavirus-2 Activity Through the Nonstructural Protein 13 Helicase Inhibition. [PDF]

ChemMedChem
Cernicchi G, Nizi MG, Emmolo R, Persoons L, Laporte M, Jochmans D, Romeo I, Pepe G, Milite C, Campiglia P, Spezzini J, Martelli A, Brogi S, Esposito F, Felicetti T, Massari S, Manfroni G, Sabatini S, Sbardella G, Alcaro S, Neyts J, Corona A, Tramontano E, De Jonghe S, Tabarrini O.   +24 more
europepmc   +1 more source