Results 81 to 90 of about 4,486 (199)

Synthesis of N-Flurbiprofen-Substituted 1,2,3,4-Tetrahydroisoquinolines

Proceedings
Isoquinoline alkaloids constitute a substantial category of natural products, among which 1,2,3,4-tetrahydroisoquinoline (THIQ) holds significance.
Diyana Dimitrova, Stanimir Manolov, Iliyan Ivanov, Dimitar Bojilov   +3 more
doaj   +1 more source

Involvement of the opioid system in the development and expression of sensitization to the locomotor-activating effect of ethanol [PDF]

, 2000
Previous studies have shown that pretreatment with naloxone (Nlx), an opiate antagonist, attenuates the stimulating effect of ethanol. the purpose of the present study was to determine the influence of Nix on the development and expression of the ...
Calil, Helena Maria, Camarini, Rosana, Pires, Maria Laura Nogueira   +2 more
core   +1 more source

A Class of Promising Acaricidal Tetrahydroisoquinoline Derivatives: Synthesis, Biological Evaluation and Structure-Activity Relationships

Molecules, 2014
As part of our continuing research on isoquinoline acaricidal drugs, this paper reports the preparation of a series of the 2-aryl-1-cyano-1,2,3,4-tetrahydroisoquinolines with various substituents on the N-phenyl ring, their in vitro acaricidal activities
Rui Yang, Qiao Ruan, Bing-Yu Zhang, Zuo-Lue Zheng, Fang Miao, Le Zhou, Hui-Ling Geng   +6 more
doaj   +1 more source

Deep Eutectic Solvents: The Organic Reaction Medium of the Century [PDF]

, 2016
This microreview summarizes the use of deep eutectic solvents (DESs) and related melts in organic synthesis. Solvents of this type combine the great advantages of other proposed environmentally benign alternative solvents, such as low toxicity, high ...
Abbott, Abbott, Abbott, Abbott, Abbott, Abbott, Abbott, Abo-Hamad, Amelio, Aparicio, Assanosi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Bafti, Bakavoli, Beckman, Bednarz, Borse, Cao, Cardellini, Carriazo, Chahdoura, Chai, Chaskar, Chen, Chen, Constable, Cragg, Dai, Dai, Dai, Dai, Davey, De Oliveira Vigier, De Oliveira Vigier, De Santi, del Monte, Disale, Domínguez de María, Domínguez de María, Duan, Dupont, Durand, Díaz-Álvarez, Earle, Ferreira, Fischer, Francisco, Gambino, García, García-Verdugo, García-Álvarez, García-Álvarez, Gill, Gore, Gorke, Gu, Guajardo, Gupta, Hallet, Handy, Handy, Handy, Hari, Hawkins, Hayyan, Henderson, Hu, Hu, Ilgen, Ilgen, Imperato, Imperato, Imperato, Itoh, Jella, Jérôme, Karmakar, Kemeling, Keshavarzipour, Khandelwal, Krishnakumar, Kumar, Kus, Laird, Lavilla, Li, Li, Li, Li, Lindström, Liu, Liu, Liu, Lobo, Lobo, Lu, Macaev, Machida, Mahboub, Mallardo, Martins, Matsuda, Maugeri, Maugeri, Maugeri, Mobinikhaledi, Morales, More, Müller, Müller, Pace, Pal, Pandey, Patil, Pavia, Pawar, Pednekar, Pena-Pereira, Pena-Pereira, Peters, Phadtare, Phadtare, Pincock, Pérez, Pérez-Sánchez, Radošević, Rastogi, Reddy, Rodríguez-Álvarez, Ruß, Saberi, Sanap, Sanap, Santos, Sassone, Scholten, Serrano, Sheldon, Shuklov, Singh, Singh, Singh, Singh, Singh, Smith, Sonawane, Steinrück, Stepankova, Sunitha, Tanaka, Tang, Tang, Vidal, Vidal, Vidal, Wagle, Wang, Wang, Wang, Wang, Wang, Wang, Wasserscheid, Welton, Xia, Yadav, Yadav, Yadav, Yu, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao   +192 more
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Enzyme catalysed Pictet-Spengler formation of chiral 1,1’-disubstituted- and spiro-tetrahydroisoquinolines

Nature Communications, 2017
The Pictet-Spengler condensation of β-arylethylamine and carbonyl compounds is an important step in the synthesis of bioactive alkaloids. Here, the authors report a Pictet-Spengler reaction between dopamine and unactivated ketones catalysed by ...
Benjamin R. Lichman, Jianxiong Zhao, Helen C. Hailes, John M. Ward   +3 more
doaj   +1 more source

Elektronenstoßinduzierte Spaltung der Stilben Doppelbindung; 1. Teil: Synthese von Stilbenen mit o-ständiger C2-Seitenkette und deuterierten Analogen [PDF]

, 1986
Syntheses of o-(ß-aminoethyl)-stilbene-urethanes (types 1, 2 and 3) and o-(ß-phenethyl)- stilbenes 4 are described. The urethanes are obtained by degradation of 1-benzyl-1,2,3,4-tetrahydroisoquinolines with ethylchloroformate; 4 is synthesized by ...
Mayer, K. K., Prior, S., Wiegrebe, Wolfgang   +2 more
core  

Antiplasmodial ealapasamines A-C,'mixed' naphthylisoquinoline dimers from the Central African liana Ancistrocladus ealaensis [PDF]

, 2017
Three unusual heterodimeric naphthylisoquinoline alkaloids, named ealapasamines A-C (1-3), were isolated from the leaves of the tropical plant Ancistrocladus ealaensis J. Léonard.
Bringmann, Gerhard, Brun, Reto, Feineis, Doris, Kaiser, Marcel, Mudogo, Virima, Tshitenge, Dieudonné Tshitenge   +5 more
core   +1 more source

Nachweis der Inversion bei der Umsetzung optisch aktiver 1-(o-Hydroxymethyl-benzyl)-N-methyl-1,2,3,4-tetrahydroisochinoline zu 3-Phenylisochromanen [PDF]

, 1982
Optisch aktive l-(2-Hydroxymethyl-benzyl)-N-methyl-l,2,3,4-tetrahydroisochinoline reagieren mit Chlorameisensäureethylester (CAE) zu optisch aktiven 3-Phenylisochromanen.
Mayer, K. K., Prior, S., Wiegrebe, Wolfgang   +2 more
core  

Chronic ethanol attenuates centrally-mediated hypotension elicited via alpha-2-adrenergic, but not I1-imidazoline, receptor activation in female rats [PDF]

, 2009
Aims—This study dealt with the effect of chronic ethanol administration on hemodynamic responses elicited by α2-adrenergic (α-methyldopa) or I1-imidazoline (rilmenidine) receptor activation in telemetered female rats. Main methods—The effects of
Abdel A. Abdel-Rahman, Abdel-Rahman, Badoer, Biaggioni, Bousquet, Bousquet, Chan, Collins, Dupuy, El-Mas, El-Mas, El-Mas, El-Mas, El-Mas, El-Mas, El-Mas, El-Mas, Elghozi, Ernsberger, Girard, Janssen, Karkanias, Kohno, Kubo, Laurent, Lokhandwala, Mahmoud M. El-Mas, Piletz, Puddey, Sgoifo, Stein, Sweet, Szmigielski, Timio, Timmermans, Tobe, Tulen, van der Maas, van Zwieten, van Zwieten, Volicer   +40 more
core   +1 more source

Stereoselective oxidative C3–N bond dehydrogenation and aromatization of 1-carboxyl substituted tetrahydroisoquinolines employing pipecolate oxidase

Green Synthesis and Catalysis
The dehydrogenation of C–N bond in 1,2,3,4-tetrahydroisoquinolines (THIQs), especially 1-substituted THIQs, is a type of fascinating transformation owing to its utility in synthetic organic chemistry. Yet, the existing reports are limitedly known as C1–N
Shuyun Ju, Xiaoshu Zhou, Huanhuan Jin, Yang Yang, Lirong Yang, Jianping Wu   +5 more
doaj   +1 more source