Results 91 to 100 of about 4,486 (199)

Studies on tetrahydroisoquinolines. XXVI. A biomimetic synthesis of 5-oxygenated 1,2,3,4-tetrahydroisoquinolines.

Chemical and Pharmaceutical Bulletin, 1986
Treatment with acetic anhydride-conc. sulufuric acid of o-quinol acetates (7, 11, 18, 19, 20, 28 and 34), which were derived from the corresponding 6-hydroxy-7-methoxytetrahydroisoquinolines (6, 12, 15, 16, 17, 27 and 31), gave the 5, 6-diacetates (8, 13, 21, 22, 23, 29 and 33, respectively). The diacetates were transformed into the corresponding 5, 6,
HIROSHI HARA, AKIRA TSUNASHIMA, HIROSHI SHINOKI, TOSHIFUMI AKIBA, OSAMU HOSHINO, BUNSUKE UMEZAWA   +5 more
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Tetrahydroisoquinoline derivatives: a new perspective on monoaminergic dysfunction in children with ADHD?

Behavioral and Brain Functions, 2007
Background The dopamine-derived tetrahydroisoquinolines (TIQ) synthesized endogeneously from aldehydes and catecholamines have shown to modulate neurotransmission, central metabolism and motor activity. Converging evidence has implicated abnormalities of
Rothenberger Aribert, Hünnerkopf Regina, Riederer Franz, Walitza Susanne, Roessner Veit, Gerlach Manfred, Moser Andreas   +6 more
doaj   +1 more source

Employing Mechanochemistry in the Synthesis of N-Ibuprofen-Substituted 1,2,3,4-Tetrahydroisoquinolines

Proceedings
Mechanochemistry has emerged as a potential alternative for organic transformations, leveraging substrate availability, stability, and reduced solvent use.
Stanimir Manolov, Diyana Dimitrova, Iliyan Ivanov, Dimitar Bojilov   +3 more
doaj   +1 more source

Recent advances in visible light-induced C1(sp3)-H functionalization of tetrahydroisoquinolines for C–C bond formation

Green Chemistry Letters and Reviews
Tetrahydroisoquinolines (THIQs) are a significant class of nitrogen-containing heterocyclic compounds often occurring in natural products and pharmaceuticals, exhibiting excellent biological activities and chemical properties, and also having a wide ...
Kai Yang, Hanqing Wu, Xinlei Fu, Shen Shan, Ruoying Hu, Zhaowen Liu   +5 more
doaj   +1 more source

Chiral N-acyliminium ions as new tools in the asymmetric synthesis of CNS-active compounds [PDF]

, 1994
Beutler, Comins, Gray, Hellmann, Irie, K.Th. Wanner, Kiguchi, Wanner, Wanner, Wong   +9 more
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Enantiopure 3-methyl-3,4-dihydroisocoumarins and 3-methyl-1,2,3,4-tetrahydroisoquinolines via chemoenzymatic asymmetric transformations [PDF]

, 2012
Busto García, Benjamín Eduardo, Gotor Fernández, Vicente, Gotor Santamaría, Vicente Miguel, Mangas Sánchez, Juan   +3 more
core   +1 more source

Dicentrine: The Major Alkaloid of Cyclea laxiflara Miers [PDF]

, 1991
The major alkaloid of Cyclea laxiflora Miers.
Ismail, Norhayati, Lajis, Md Nordin, Samadi, Zainuddin   +2 more
core  

New tetrahydroisoquinolines bearing nitrophenyl group targeting HSP90 and RET enzymes: synthesis, characterization and biological evaluation

BMC Chemistry
In this study, new tetrahydroisoquinoline compounds were synthesized by reaction of 7-Acetyl-4-cyano-1,6-dimethyl-6-hydroxy-8- (3-nitrophenyl or 4-nitrophenyl)-5,6,7,8-tetrahydrosoquinoline-3(2H)-thiones with methyl iodide, chloro acetonitrile, ethyl ...
Etify A. Bakhite, Reda Hassanien, Nasser Farhan, Eman M. Sayed, Marwa Sharaky   +4 more
doaj   +1 more source

Enantioselective palladium(0)-catalyzed C-H arylation strategy for chiral heterocycles [PDF]

, 2017
Transition-metal-catalyzed C-H functionalizations have emerged as complementary and powerful tools to access molecular complexity from widely available starting materials.
Cramer, Nicolai, Saget, Tanguy
core  

HARMACOLOGY OF 1,2,3,4-TETRAHYDROISOQUINOLINES

Journal of Research in Pharmacy, 2023
Tursunkhodzhaeva F.M, Azamatov A.A.
openaire   +1 more source