Results 111 to 120 of about 3,627 (215)

Inhibition of Cyclic Strain-Induced Endothelin-1 Secretion by Tetramethylpyrazine

, 2009
1. Chuanxiong is a Chinese herb that has been used widely in China to treat vascular disorders. 2,3,5,6- Tetramethylpyrazine (TMP) is one of the major components purified from chuanxiong.
張念中;陳錦澤;王子哲;楊紅玉, CHANG, NEN-CHUNG;CHEN, JIN-JER;WANG, TZE-CHE;YANG, HUNG-YU   +1 more
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Analgesic effect of tetramethylpyrazine on neuropathic pain rats and its effects on voltage gated calcium channels in dorsal root ganglion neurons [PDF]

, 2017
目的：应用脊神经结扎（Spinalnerveligation，SNL）制作神经病理痛（Neuropathicpain，NP）大鼠模型，给予不同剂量川芎嗪（Tetramethylpyzine，TMP）治疗，检测神经病理痛大鼠的机械缩足反应阈值（Mechanicalwithdrawlthreshold，MWT）和热缩足潜伏期（Thermalwithdrawllatency，TWL）及伴随的抑郁行为，探讨川芎嗪对神经病理痛的镇痛作用，神经病理痛模型大鼠是否表现出抑郁行为 ...
郭金华
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Tetramethylpyrazine inhibits production of nitric oxide and inducible nitric oxide synthase in lipopolysaccharide-induced N9 microglial cells through blockade of MAPK and PI3K/Akt signaling pathways, and suppression of intracellular reactive oxygen species

, 2010
Aim of the study: To determine the inhibitory effect of tetramethylpyrazine (TMP) on lipopolysaccharide (LPS)-induced over-production of nitric oxide (NO) and inducible nitric oxide synthase (iNOS) in N9 microglial ...
Wang, Ying-Xiong, Li, Wen-Ming, Liu, Hong-Tao, He, Jun-Lin, Chen, Wen-Juan, Yu, Chao, Yang, Zhu, Du, Yu-Guang   +7 more
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Tetramethylpyrazine and renal ischemia-reperfusion injury: a systematic review and meta-analysis of preclinical studies

Frontiers in Pharmacology
ObjectivesThe aim of this systematic review and meta-analysis is to synthesize the effects and mechanisms of Tetramethylpyrazine (TMP) on renal outcomes in animal models of renal I/R injury.MethodsAnimal studies from seven electronic databases were ...
Zhongmei Fu, Lianyan Jiang, Xiaojuan Su, Hua Wang, Mingquan Li   +4 more
doaj   +1 more source

Tetramethylpyrazine production by immobilized culture of Lactococcus lactis subsp. lactis biovar. diacetilactis FC1

, 2020
Acetoin and ammonia, the precursors of tetramethylpyrazine (TMP) having "meaty" or "roasted" flavors, were produced by the culture of Lactococcus lactis ssp. lactis biovar. diacetilactis FC1 in free and
우건조
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Beneficial effects of combined terlipressin and tetramethylpyrazine administration on portal hypertensive rats

, 1999
The purpose of this study was to investigate the therapeutic effects of terlipressin (TP) alone or in combination with tetramethylpyrazine (TMP) on anesthetized portal hypertensive rats.
Chuang-Ye Hong, Ke-Ji Chen, Fang-Chi Chang, Yi-Tsau Huang, Jaung-Geng Lin, Han-Chieh Lin   +5 more
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Tetramethylpyrazine inhibits ferroptosis in spinal cord injury by regulating iron metabolism through the NRF2/ARE pathway

Frontiers in Pharmacology
BackgroundTetramethylpyrazine (TMP) is a natural alkaloid compound with antioxidant and neuroprotective effects. We hypothesized that TMP could exert neuroprotective effects by inhibiting ferroptosis through modulating iron metabolism, but its mechanism ...
Jingwei Tao, Jingwei Tao, Jingya Zhou, Hanjie Zhu, Lin Xu, Jizhou Yang, Xiaohong Mu, Xiao Fan   +7 more
doaj   +1 more source

Protection by Tetramethylpyrazine in acute absolute ethanol-induced gastric lesion

, 2016
[[abstract]]Acute oral administration of absolute ethanol (1.0 ml/kg) to fasting rats produced extensive necrosis of the gastric mucosa within 1 h. Pretreatment 30 min before administration of ethanol with oral tetramethylpyrazine (TMP) prevented this ...
劉吉豐, Liu, Chi-Feng;Lin, Chun-Ching;Ng, Lean-Teik;Lin, Song-Chow   +1 more
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Tetramethylpyrazine protects mice against thioacetamide-induced acuted hepatotoxicity

, 2016
[[abstract]]In this study, the intraperitoneal administration of 1 mg/kg thioacetamide (TAA) produced hepatotoxicity in mice. The increase in serum SGOT and SGPT produced at 24 h by this regimen was decreased in a dose-dependent manner by ...
劉吉豐, So, EC;Wong, KL;Huang, TC;Tasi, SC;Liu, CF   +1 more
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The (2:1) complex of picric acid with tetramethylpyrazine. The structure,l IR spectra and tunnel splitting of methyl groups

, 2010
The crystal structure of 2:1 picric acid (PAH) with tetramethylpyrazine (TMP) was determined by using X-ray diffraction studies. Two equivalent N+-H center dot center dot center dot O- hydrogen bonds are formed with the length of 2.601 angstrom ...
Pawlukojc, A., Wuttke, J., Sawka-Dobrowolska, W., Sobczyk, L., Bator, G., Grech, E., Nowicka-Scheibe, J.   +6 more
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