Results 121 to 130 of about 3,627 (215)

Antioxidative effects of tetramethylpyrazine on ethanol-induced lipid peroxidaion

, 2016
[[abstract]]Acute p.o. administration of 99.5% ethanol (0.1 ml) to fasted mice produced heart toxicity. Pretreatment with p.o. administration of tetramethylpyrazine (TMP) could prevent such toxicity effectively and dose-dependently.
劉吉豐, Liu, Chi-Feng;Lin, Chia-Hsien;Chen, Chin-Fa;Huang, Tian-Chyuan;Lin, Song-Chow   +1 more
core  

Tetramethylpyrazine suppresses interleukin-8 expression in LPS-stimulated human umbilical vein endothelial cell by blocking ERK, p38 and nulear factor-kappa B signaling pathways

, 2009
Aim of the study: To determine the anti-inflammatory effects of Tetramethylpyrazine (TMP) and to investigate the inhibitory effect of TMP on IL-8 production in human umbilical vein endothelial cells (HUVECs) induced by LIPS might be mediated by ...
Li, Wen-Ming, Liu, Hong-Tao, He, Jun-Lin, Yu, Chao, Li, Xiu-Ying   +4 more
core   +1 more source

Effect of tetramethylpyrazine on lipid peroxidation in strptozotocin-induced diabetic mice

, 2016
[[abstract]]Oxygen free radicals have been suggested to be a contributory factor in complications of diabetes mellitus. In the present study, we investigated the effect of tetramethylpyrazine (TMP) (10, 25 and 50 mg/kg), an active component of a Chinese ...
劉吉豐, Lee, Liang-Ming;Liu, Chi-Feng;Yang, Pao-Pao   +1 more
core  

Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis.

, 2014
Tetramethylpyrazine (TMP) is an active compound isolated from a Chinese herbal prescription that is widely used in traditional Chinese medicine for the treatment of inflammatory and cardiovascular diseases.
Pu Xia, Xi Li, Qiong Xu, Zhenqi Liu, Wei Wang, Xin Gao   +5 more
core   +1 more source

Synergistic protective effect of astragaloside IV–tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia

, 2012
Ethnopharmacological relevanceAstragaloside IV and tetramethylpyrazine have been extensively used in the cardio-cerbrovascular diseases of medicine as a chief ingredient of glycoside or alkaloid formulations for the treatment of stroke and myocardial ...
Yang, Jiehong, Zhang, Yuyan, Li, Jinhui, Lu, Jing, Zhu, Zhenhong, Wan, Haitong   +5 more
core   +1 more source

Anti-apoptotic and neuroprotective effects of Tetramethylpyrazine following spinal cord ischemia in rabbits

, 2006
Background Tetramethylpyrazine (TMP) is one of the most important active ingredients of a Chinese herb Ligusticum wallichii Franchat, which is widely used in many ischemia disorders treatments.
Wang Kun-Zheng, Wang Chun-Sheng, Dang Xiao-Qian, Cheng Bin, Fan Li-Hong   +4 more
core   +1 more source

Tetramethylpyrazine attenuates oleic acid-induced acute lung injury/acute respiratory distress syndrome through the downregulation of nuclear factor-kappa B (NF-kB) activation in rats

, 2013
The aim of this study was to investigate the anti-inflammatory activities of tetramethylpyrazine (TMP) in the mice model of acute lung injury/acute respiratory distress syndrome (ALI/ARDS) induced by oleic acid (0.15 ml/kg, intravenous (i.v.)). We report
Wan, D, Liu, D, Xu, F, Leng, WY, Zho, FC
core   +1 more source

Protective effect of tetramethylpyrazine on absolute ethanol-induced renal toxicity-in mice

, 2016
[[abstract]]Acute administration of absolute ethanol (10 ml/kg) per os to fasted mice produced extensive renal failure as measured by a rise in blood urea nitrogen and creatinine.
劉吉豐, Liu, CF;Lin, MH;Lin, CC;Chang, HW;Lin, SC   +1 more
core  

Tetramethylpyrazine potentiates arsenic trioxide activity against HL-60 cell lines

, 2012
The objective of this study was to evaluate the effects of tetramethylpyrazine (TMP) in combination with arsenic trioxide (As2O3) on the proliferation and differentiation of HL-60 cells.
Cuicui Wang, Gaili Guo, Youhua Xu, Yuni Wu, Tiantian Hu, Yali Shen   +5 more
core  

Pyrazine-based fingerprinting for geographical origin discrimination of coffee: integrating chemometrics and machine learning. [PDF]

Food Chem X
Lian M, Zheng W, Zhang Q, Xu H, Hou S, Chen X, Chen Q, Chen J.   +7 more
europepmc   +1 more source