Results 131 to 140 of about 4,590 (177)
Histo-Molecular Intratumoral Heterogeneity in Meningiomas: A Narrative Review. [PDF]
Cancers (Basel)Bankole NDA +16 more
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Tetraploidy and tumor development [PDF]
Cancer Cell, 2005 In tumorigenesis, aneuploidy is frequently preceded by tetraploidy. Major issues include how tetraploidy arises and how cells can effectively respond to this state. Two recent papers address these issues. Shi and King demonstrate that nondisjunction of chromosomes in mitosis frequently results in tetraploidy through mitotic cleavage failure.
Robert L Margolis
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Canadian Journal of Research, 1946
Tetraploid forms of the flax variety, Redwing, and the F1 flax hybrid, Bison × Redwing, were most easily obtained by treatment of the epicotyl of seedlings with colchicine in lanolin emulsion. Seeds of the tetraploid forms were considerably larger than those of the diploid; but, because of their lower fertility and later maturity, yield and quality ...
J G, ROSS, J W, BOYES
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Tetraploid forms of the flax variety, Redwing, and the F1 flax hybrid, Bison × Redwing, were most easily obtained by treatment of the epicotyl of seedlings with colchicine in lanolin emulsion. Seeds of the tetraploid forms were considerably larger than those of the diploid; but, because of their lower fertility and later maturity, yield and quality ...
J G, ROSS, J W, BOYES
openaire +2 more sources
Tetraploidy/near-tetraploidy acute myeloid leukemia
Leukemia Research, 2017A tetraploid/near tetraploid (T/NT) karyotype is a rare finding in acute myeloid leukemia (AML). Here we report 38 AML patients with a T/NT karyotype, including 26 men and 12 women with a median age of 65 years. T/NT karyotype was detected at initial diagnosis of AML in 16 patients, and acquired during the course of disease in 22 patients. All patients
Lanshan, Huang +9 more
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Prenatal Diagnosis of Tetraploidy
Fetal Diagnosis and Therapy, 2009A pregnancy was terminated at 24 weeks of amenorrhea when tetraploidy (92 XXXX) was diagnosed in fetal blood subsequent to ultrasonographic detection of a polymalformation syndrome. The severity of the neurological deficit in tetra-ploid infants and their death befor 2 years of age require that prenatal diagnosis by cordocentesis be performed for ...
P, Sagot +6 more
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Mosaic tetraploidy in a male neonate
Clinical Genetics, 1982Though complete and mosaic tetraploidy in zygotes almost always leads to abortion early in pregnancy, some cases have been described in which development was more successful. We report a male neonate with microcephaly and various other anomalies, in whom tetraploidy was found in 16% of peripheral lymphocytes.
H, Veenema, E W, Tasseron, J P, Geraedts
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A liveborn infant with tetraploidy
American Journal of Medical Genetics, 1988AbstractWe report on an 22‐month‐old white girl with tetraploidy who is growing well, but who is extremely delayed in psychomotor development. When counseling parents it is important to realize that, although quite rare, tetraploid individuals can be born alive and live for at least 22 moths. The implications are also relevant to prenatal diagnosis.
C. Z. Lafer +3 more
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Tetraploidy, aneuploidy and cancer
Current Opinion in Genetics & Development, 2007Aneuploidy is one of the most obvious differences between normal and cancer cells. However, there remains debate over how aneuploid cells arise and whether or not they are a cause or consequence of tumorigenesis. One proposed route to aneuploid cancer cells is through an unstable tetraploid intermediate. Supporting this idea, recent studies demonstrate
Neil J, Ganem +2 more
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Neuropathology and Applied Neurobiology, 1977
Cells with tetraploid nuclei have been examined in the striate cortex of patients with visual impairment and compared with age and sex matched controls. The number of these nuclei is reduced in those with visual impairment suggesting that tetraploidy is dependent upon an intact visual pathway and may be related to visual experience and memory.
C. L. SCHOLTZ, D. M. A. MANN
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Cells with tetraploid nuclei have been examined in the striate cortex of patients with visual impairment and compared with age and sex matched controls. The number of these nuclei is reduced in those with visual impairment suggesting that tetraploidy is dependent upon an intact visual pathway and may be related to visual experience and memory.
C. L. SCHOLTZ, D. M. A. MANN
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