Results 141 to 150 of about 4,590 (177)
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Tetraploidy and the striate cortex
Pathology, 1977A tetraploid population of glial cell nuclei has been identified in layers one, two and three of the entire striate cortex. These have approximately twice the volume of diploid glial cell nuclei.
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Leukemia and Lymphoma
Near-tetraploidy/tetraploidy (NT/T) is a cytogenetic alteration in acute myeloid leukemia (AML). In AML, specific chromosomal alterations are associated with clinical, morphological, and immunophenotypic features. The impact of cytogenetics on the prognosis of AML is well established.
Billie Carstens, Mary Haag
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Near-tetraploidy/tetraploidy (NT/T) is a cytogenetic alteration in acute myeloid leukemia (AML). In AML, specific chromosomal alterations are associated with clinical, morphological, and immunophenotypic features. The impact of cytogenetics on the prognosis of AML is well established.
Billie Carstens, Mary Haag
exaly +3 more sources
Tetraploidy in BRCA2 breast tumours
European Journal of Cancer, 2012Tetraploidy and aneuploidy can be caused by cell division errors and are frequently observed in many human carcinomas. We have recently reported delayed cytokinesis in primary human fibroblasts from BRCA2 mutation carriers, implying a function for the BRCA2 tumour suppressor in completion of cell division.
Asta Bjork, Jonsdottir +5 more
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Development of tetraploidy in V79 spheroids
In Vitro, 1982Chinese hamster V-79-171 cells, when placed in suspension culture, spontaneously form multicell spheroids. As the spheroids enlarge the fraction of polyploid (predominantly tetraploid) cells increases and can approach 100% in very large spheroids. Spheroid size, rather than age, seems to be a major determinant for increased ploidy. When cell separation
P L, Olive, J C, Leonard, R E, Durand
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Nature, 1936
A COMMUNICATION1 from B. R. Speicher has directed attention to certain genetical data which do not seem to favour my suggestion2 that the pre-conjugation phenomena observed in the gametogenesis of the honey bee and of Cynips kollari may be interpreted in terms of derived tetraploidy.
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A COMMUNICATION1 from B. R. Speicher has directed attention to certain genetical data which do not seem to favour my suggestion2 that the pre-conjugation phenomena observed in the gametogenesis of the honey bee and of Cynips kollari may be interpreted in terms of derived tetraploidy.
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Gynecologic and Obstetric Investigation, 2010
17 cases of partial molar pregnancy were analysed cytogenetically by the direct-preparation method. Eight partial moles were triploid, 7 diploid/tetraploid mosaic, and 2 tetraploid. In the course of prenatal cytogenetic screening, out of 1,263 chorionic villus samplings, 2 tetraploid and 1 diploid/tetraploid cases were found.
Andrá;s Tóth +5 more
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17 cases of partial molar pregnancy were analysed cytogenetically by the direct-preparation method. Eight partial moles were triploid, 7 diploid/tetraploid mosaic, and 2 tetraploid. In the course of prenatal cytogenetic screening, out of 1,263 chorionic villus samplings, 2 tetraploid and 1 diploid/tetraploid cases were found.
Andrá;s Tóth +5 more
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G1 tetraploidy checkpoint and the suppression of tumorigenesis
Journal of Cellular Biochemistry, 2002AbstractCheckpoints suppress improper cell cycle progression to ensure that cells maintain the integrity of their genome. During mitosis, a metaphase checkpoint requires the integration of all chromosomes into a metaphase array in the mitotic spindle prior to mitotic exit. Still, mitotic errors occur in mammalian cells with a relatively high frequency.
Robert L, Margolis +2 more
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Tetraploidy inProtopterus (Dipnoi)
Experientia, 1980Comparative DNA values obtained by Feulgen cytophotometry for 3 species ofProtopterus, as well as karyotype analysis, show the existence of a diploid-tetraploid relationship within the genusProtopterus.
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