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Tetrazole: A privileged scaffold for the discovery of anticancer agents

Chemical Biology and Drug Design, 2022
Carcinoma, characterized by abnormal growth of cells and tissue, is a ubiquitously leading cause of mortality across the globe due to some carcinogenic factors. Currently, several anticancer agents are commercially available in the global market. However,
A. Verma   +7 more
semanticscholar   +1 more source

Nitroimino-tetrazolates and Oxy-nitroimino-tetrazolates

Journal of the American Chemical Society, 2010
Highly energetic 1,1'-ethylenebis(oxy)bis(5-nitroimino-tetrazolate) salts were obtained by reacting equimolar quantities of the acidic 1,1'-ethylenebis(oxy)bis(5-nitroimino-tetrazole) and energetic bases in aqueous solution. Additionally, metathesis of silver 1,1'-ethylenebis(oxy)bis(5-nitroimino-tetrazolate) with diaminoguanidinium chloride or ...
Young-Hyuk, Joo, Jean'ne M, Shreeve
openaire   +2 more sources

Tetrazole Azasydnone (C2N7O2H) And Its Salts: High-Performing Zwitterionic Energetic Materials Containing A Unique Explosophore.

Chemistry, 2020
We report the first compound containing both a tetrazole and an azasydnone ring, a unique energetic material.   Several energetic salts of the tetrazole azasydnone were synthesized and characterized, leading to the creation of new secondary and primary ...
Matthew L. Gettings   +5 more
semanticscholar   +1 more source

A Series of Polyoxometalate-Based Metal–Bis(pyridyl-tetrazole) Complexes with High Electrocatalytic Activity for Hydrogen Evolution Reaction in Alkaline and Acid Media

, 2020
In this work, a succession of Keggin-type polyoxometalate (POM)-based metal–bis(pyridyl-tetrazole) complexes, {Cu2(3-bptzp)3(H2O)4[SiW12O40]}·H2O (1), {Cu2(3-bptzpe)2(H2O)8[SiW12O40]}·4H2O (2), and...
X. Wang   +3 more
semanticscholar   +1 more source

Tetrazoles: XLV. Amidoalkylation of 5-Substituted Tetrazoles

Russian Journal of Organic Chemistry, 2003
Amidoalkylation of 5-aryl(hetaryl)tetrazoles with N-hydroxymethylamides of aliphatic and aromatic carboxylic acids occurs regioselectively and yields mainly 5-aryl(hetaryl)-2-acylaminomethyltetrazoles. These compounds arefairly stable in neutral media but are smoothly deprotected by the action of aqueous sodium hydroxide or hydrochloric acid.
L. V. Myznikov   +3 more
openaire   +1 more source

Unexpected Cyclization Product Discovery from the Photoinduced Bioconjugation Chemistry between Tetrazole and Amine.

Journal of the American Chemical Society
Bioconjugation chemistry has emerged as a powerful tool for the modification of diverse biomolecules under mild conditions. Tetrazole, initially proposed as a bioorthogonal photoclick handle for 1,3-dipolar cyclization with alkenes, was later ...
Juan Zhang   +6 more
semanticscholar   +1 more source

Green Methodologies for Tetrazole Synthesis from Different Starting Materials: A Recent Update

Current organic chemistry
Tetrazole is a most versatile pharmacophore of which more than twenty FDA-approved drugs have been marketed globally for the management of various diseases. In spite of many remarkable and consistent efforts having been made by the chemists towards the
Shivangi Jaiswal   +3 more
semanticscholar   +1 more source

Tetrazoles

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

Synthesis, characterization and mechanistic study of nano chitosan tetrazole as a novel and promising platform for CRISPR delivery

International Journal of Polymeric Materials and Polymeric Biomaterials, 2020
Here, a newly modified chitosan tetrazole was synthesized and fully characterized for CRISPR technology since by increasing the ratio of nitrogen to other elements, the interaction between the genetic material and this nanomaterial was significantly ...
Navid Rabiee   +5 more
semanticscholar   +1 more source

Biologically active tetrazole scaffolds: Catalysis in magnetic nanocomposites

, 2020
Tetrazoles are an important class of nitrogen-containing heterocycles with a broad spectrum of applications in medicinal chemistry. Recent literature studies clearly showed that tetrazoles have a broad spectrum of biological and pharmacological ...
Anahita Manafi Khajeh Pasha   +3 more
semanticscholar   +1 more source

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