Enantioselective main group catalysis: modern catalysts for organic transformations [PDF]
This review highlights a number of recent developments in the field of main group enantioselective catalysis. Many essential transformations can be effected catalytically such as hydrosilylation, hydroamination and hydrogenation reactions, amongst others,
Melen, Rebecca L., Wilkins, Lewis C.
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Current Status of Research on Losartan in Tumour Therapy
ABSTRACT Losartan, a widely prescribed antihypertensive agent, has attracted growing interest as a potential adjuvant in cancer therapy due to its affordability, established safety profile and pleiotropic effects. Emerging preclinical evidence demonstrates that losartan can effectively modulate the tumour microenvironment (TME) by inhibiting ...
Han Wang, Shuang Yuan, Hongjing Wang
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An Efficient One-Pot Three-Component Synthesis of Novel Sulfanyl Tetrazoles Using Ionic Liquids
An efficient, simple, and environmentally benign method for the synthesis of novel sulfanyl tetrazoles has been achieved by one-pot three-component reaction of phenacyl bromides/3-(2-bromoacetyl)coumarins with KSCN and NaN3 using [Bmim]BF4 ionic liquid ...
Sankari Kanakaraju +2 more
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Tautomeric Equilibria Studies by Mass Spectrometry [PDF]
Tautomerism in organic chemistry has been extensively studied in condensed phase by spectrometric methods, mainly by IR and NMR techniques. Mass spectrometry studies start 40 years ago but just recently it has been recognized the importance of the mass ...
Eduardo A. Castro +3 more
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The first metal complexes of 3,3'-bi-1,2,4-oxadiazole: A curiously ignored ligand [PDF]
The crystal structure of 3,3'-bi-1,2,4-oxadiazole (1) reveals a planar centrosymmetric structure for this molecule in the solid state. It forms a mononuclear complex (3) with palladium(II) chloride, which is shown by X-ray crystallography to contain the ...
Richardson, C., Steel, P.J.
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Bioorthogonal fluorescent labels: a review on combined forces [PDF]
This review ventures to summarize the latest developments in bioorthogonal fluorescent imaging labels with a special focus on bioimaging applications. We briefly summarize the most preferred means of bioorthogonal tagging schemes for the labeling
Cserép, Balázs Gergely +2 more
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The title compound C6H12N4, is one of a few known tetrazoles with an alkyl chain in the 5-position. The asymmetric unit contains two independent molecules. The molecules are linked by N—H...N interactions into chains with graph-set notation D(2)
Heiner Detert +2 more
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Computationally motivated synthesis and enzyme kinetic evaluation of N-(β-d-glucopyranosyl)-1,2,4-triazolecarboxamides as glycogen phosphorylase inhibitors [PDF]
Following our recent study of N-(β-D-glucopyranosyl)-oxadiazole-carboxamides (Polyák et al., Biorg. Med. Chem. 2013, 21, 5738) revealed as moderate inhibitors of glycogen phosphorylase (GP), in silico docking calculations using Glide have been performed ...
Alex +57 more
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Synthesis, Characterization of Mixed Cu(II) Pyridyl Tetrazoles and 1,10-Phenanthroline Complexes - DFT and Biological Activity [PDF]
Ch. Himasekar +2 more
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