Results 111 to 120 of about 45,354 (218)

Reversible cerebral vasoconstriction syndrome: A narrative review

open access: yesHeadache: The Journal of Head and Face Pain, Volume 66, Issue 5, Page 1162-1180, May 2026.
Abstract Objectives/Background This review summarizes current insights into Reversible cerebral vasoconstriction syndrome (RCVS) diagnosis, management, and outcomes. RCVS is a cerebrovascular disorder characterized by recurrent thunderclap headaches and transient segmental vasoconstriction of cerebral arteries, typically resolving within 3 months ...
Ícaro Araújo de Sousa   +7 more
wiley   +1 more source

Predicting Structural Details of the Sodium Channel Pore Basing on Animal Toxin Studies

open access: yesFrontiers in Pharmacology, 2018
Eukaryotic voltage-gated sodium channels play key roles in physiology and are targets for many toxins and medically important drugs. Physiology, pharmacology, and general architecture of the channels has long been the subject of intensive research in ...
Denis B. Tikhonov   +2 more
doaj   +1 more source

Cells and ionic conductances contributing to spontaneous activity in bladder and urethral smooth muscle

open access: yesThe Journal of Physiology, Volume 604, Issue 9, Page 3611-3632, 1 May 2026.
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm   +3 more
wiley   +1 more source

Regional and Developmental Differences in Na+ Currents in Vestibular Primary Afferent Neurons

open access: yesFrontiers in Cellular Neuroscience, 2018
The vestibular system relays information about head position via afferent nerve fibers to the brain in the form of action potentials. Voltage-gated Na+ channels in vestibular afferents drive the initiation and propagation of action potentials, but their ...
Frances L. Meredith   +2 more
doaj   +1 more source

An improved tetrodotoxin analyzer.

open access: yesAgricultural and Biological Chemistry, 1989
In this communication, we report an improved TTX analyzer for the sensitive determination of all TTX ...
Mari Yotsu, Amane Endo, Takeshi Yasumoto
openaire   +2 more sources

Tetrodotoxin. VII. On the Structures of Tetrodotoxin and its Derivatives

open access: yesChemical and Pharmaceutical Bulletin, 1964
The structures of both tetrodonic acid hydrobromide and 6, 11-diacetylanhydrotetrodotoxin hydroiodide were established by chemical and X-ray crystallographical research. Based upon structures of both these salts and upon other chemical information, we determined that tetrodotoxin and anhydrotetrodotoxin have zwitterionic hemilactal structures.
Kyosuke Tsuda   +6 more
openaire   +3 more sources

Public Health Risks Associated with Tetrodotoxin and Its Analogues in European Waters: Recent Advances after The EFSA Scientific Opinion

open access: yesToxins, 2019
Tetrodotoxin (TTX) and its analogues are naturally occurring toxins responsible worldwide for human intoxication cases and fatalities, mainly associated with pufferfish consumption. In the last decade, TTXs were detected in marine bivalves and gastropods
Panagiota Katikou
doaj   +1 more source

High Plasma Tnf-? Levels And Mononuclear Cells Inos And Tnf-? Expression AS Risk Factors For Painful Diabetic Neuropathy [PDF]

open access: yes, 2010
Painful Diabetic Neuropathy (PDN) is one of the most common and annoyingcomplications of diabetes mellitus. The pathogenesis of PDN is complex and still unclear.Recently it has become clear that nitric oxide (NO) and proinflammatory cytokines playan ...
Purwata, T. E. (Thomas)   +3 more
core  

Neural Coding of Green Flash in Retinal Bipolar Pathways [PDF]

open access: yes, 2012
What visual information do the graded potentials among retinal bipolar pathways actually transmit from photoreceptors to ganglion cells? The answer does not exist. Even the graded electric signals have not been understood completely.
Caiping Hu
core   +1 more source

Tetrodotoxin: a brief history.

open access: yesProceedings of the Japan Academy. Series B, Physical and biological sciences, 2008
Tetrodotoxin (TTX), contained in puffer, has become an extremely popular chemical tool in the physiological and pharmacological laboratories since our discovery of its channel blocking action in the early 1960s. This brief review describes the history of discovery of TTX action on sodium channels, and represents a story primarily of my own work.
openaire   +2 more sources

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