Results 101 to 110 of about 45,354 (218)

Biomedical and pharmacological potential of tetrodotoxin-producing bacteria isolated from marine pufferfish Arothron hispidus (Muller, 1841)

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2010
Specimens of the pufferfish Arothron hispidus collected at Parangipettai, on the southeast coast of India, were subjected to bacterial isolation and identification.
S Bragadeeswaran   +3 more
doaj   +1 more source

Modeling of interstitial branching of axonal networks [PDF]

open access: yes, 2013
A single axon can generate branches connecting with plenty synaptic targets. Process of branching is very important for making connections in central nervous system.
Gafarov, F.   +2 more
core   +2 more sources

Developmental Profiling of Structural and Functional Maturation in Mouse Corpus Callosum

open access: yesGlia, Volume 74, Issue 6, June 2026.
Progressive myelin development in mouse corpus callosum is accompanied by gradual decrease in oligodendrocyte precursor cell density and increase in oligodendrocyte density. Pro‐Capase‐3 is transiently upregulated in oligodendrocyte during postnatal development.
Hayes Johnson   +4 more
wiley   +1 more source

Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]

open access: yes, 2007
Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma   +3 more
core   +1 more source

The Antipsychotic Aripiprazole Induces Cytotoxicity in Bladder Cancer Cells While Preserving Urothelial and Bladder Function

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan   +3 more
wiley   +1 more source

Effects of cromakalim (BRL 34915) on potassium conductances in CA3 neurons of the guinea-pig hippocampus in vitro [PDF]

open access: yes, 1989
The action of the potassium channel activator, cromakalim (BRL 34915), on membrane potential, input resistance and current-voltage-relationship of CA3 neurons in a slice preparation of the guinea-pig hippocampus was investigated by means of intracellular
Alzheimer, Christian   +2 more
core   +1 more source

TTX‐S/TTX‐R Na+ Currents Coordinately Fine‐Tune Depolarization/Firing Capability Revealed by Voltage Derivatives/Displacement Current Phase Plots With Dynamic Current‐Clamp Simulation in Rat Visceral Sensory Neurons

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim To investigate how tetrodotoxin‐sensitive (TTX‐S) and tetrodotoxin‐resistant (TTX‐R) Na+ channels coordinately fine‐tune action potential (AP) depolarization and firing capability in rat nodose visceral sensory neurons. Methods APs were recorded by ruptured‐patch current clamp in unmyelinated C‐type and myelinated Ah‐type neurons from ...
Zhang Jing‐ran   +6 more
wiley   +1 more source

Increase in neuroexcitability of unmyelinated C-type vagal ganglion neurons during initial postnatal development of visceral afferent reflex functions [PDF]

open access: yes, 2013
BACKGROUND: Baroreflex gain increase up closely to adult level during initial postnatal weeks, and any interruption within this period will increase the risk of cardiovascular problems in later of life span. We hypothesize that this short period after
Cao, Pan‐Xiang   +13 more
core   +2 more sources

A role for epithelium‐derived 6‐nitrodopamine on human ureter contractility

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2360-2375, May 2026.
Abstract Background and Purpose To investigate the basal release of 6‐nitrodopamine (6‐ND) from human isolated ureter and the role of this novel catecholamine in the ureter contractility. Experimental Approach Ureters from 67 brain‐dead organ donors (40 males and 27 females) were used during kidney transplantation procedures.
Wilmar Azal Neto   +12 more
wiley   +1 more source

Diabetes-induced alterations in urothelium function:Enhanced ATP release and nerve-evoked contractions in the streptozotocin rat bladder [PDF]

open access: yes, 2018
Up to 80% of patients with diabetes mellitus develop lower urinary tract complications, most commonly diabetic bladder dysfunction (DBD). The aim of this study was to investigate the impact of diabetes on the function of the inner bladder lining ...
Apodaca   +56 more
core   +1 more source

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