Results 101 to 110 of about 19,032 (194)

Effect of tetrodotoxin (TTX) on action potential generation.

open access: yes, 2012
Application of TTX led to a slowing in spontaneous action potential generation in hiPSC-CMs (A) but did not stop AP generation whereas TTX completely abolished AP generation in hESC-CMs at 10 µM concentration (B). Overlay of representative traces display
Xiaowu Sheng (131836)   +6 more
core   +1 more source

Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior

open access: yes, 2006
The S100 family protein p11 (S100A10, annexin 2 light chain) is involved in the trafficking of the voltage-gated sodium channel Na(V)1.8, TWIK-related acid-sensitive K+ channel (TASK-1), the ligand-gated ion channels acid-sensing ion channel 1a (ASIC1a ...
Foulkes, T   +8 more
core  

Toxins of Pufferfish That Cause Human Intoxications [PDF]

open access: yes, 2010
Many marine pufferfish possess a potent neurotoxin, tetrodotoxin (TTX). In general, they have strong toxicity in the liver and ovary, leading to a frequent occurrence of human poisonings. TTX is originally produced by marine bacteria and distributes over
Arakawa, Osamu   +3 more
core  

Tetrodotoxine (TTX) in mosselen: Accumulatie experiment verswaterleiding Kijkuit, Yerseke

open access: yes, 2016
In verband met de overschrijding van de concentratie tetrodotoxine (TTX) in het schelpdiervlees van oesters en mosselen in de Kom van de Oosterschelde (inclusief de verwaterpercelen) is dit gebied eind juni 2016, evenals de noordelijke tak van de Oosterschelde, gesloten voor schelpdierproductie en als verwatergebied.
Wijsman, J.W.M., Poelman, M.
openaire   +1 more source

Neuroplastic alteration of TTX-resistant sodium channel with visceral pain and morphine-induced hyperalgesia

open access: yes, 2012
Jinghong Chen,1,2,4 Ze-hui Gong,4 Hao Yan,2 Zhijun Qiao,3 Bo-yi Qin41Department of Internal Medicine, Neuroscience Program, The University of Texas Medical Branch, Galveston, TX, USA; 2The Divisions of Pharmacy, Pharmacology core lab, MD Anderson Cancer ...
Chen J, Gong Z, Yan H, Qiao Z, Qin B
core  

Tetrodotoxin has no effect on pilocarpine-induced fluid secretion in perfused submandibular glands of rats.

open access: yes, 2019
(a) Profile of secretion of salivary fluid in response to pilocarpine treatment in the presence or absence of tetrodotoxin (TTX) in submandibular glands of rats. Submandibular glands were stimulated with 10 μM pilocarpine in the absence of TTX.
Takanori Narita (25602)   +3 more
core   +1 more source

Purification and Characterization of Tetrodotoxin-binding Substance in Shore Crab Hemolymph

open access: yes, 2001
P(論文)テトロドトキシン(TTX)は古くからフグ毒の主成分として知られる。1964年にカリフォルニアイモリの毒がTTXに同定されて以来,これまでに微生物から両生類にいたる多種の生物に存在することが明らかにされてきた。TTXは神経細胞のNaチャンネルを選択的にブロックして,神経の興奮を阻害する作用を持つ神経毒であるとされている。TTXを保有しない一般の硬骨魚類のTTXの腹腔内投与に対する抵抗性はマウスと同程度の体重20g当たり約1MUである。これに対して ...
楠田, 理一   +9 more
core   +1 more source

The Potential Mechanisms of Althaea rosea (Linn.) Cavan. Flower in Alleviating Tetrodotoxin Poisoning: An Integrated Metabolomics, Network Pharmacology and Experimental Validation

open access: yesDrug Design, Development and Therapy
Renjin Zheng,1,2 Youjia Wu,1 Lingyi Huang,1 Fanxiang Zeng,3 Liying Huang1 1School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, 350122, People’s Republic of China; 2Physical and Chemical Analysis Department, Fujian Center for Disease Control ...
Zheng R, Wu Y, Huang L, Zeng F, Huang L
doaj  

First Detection of Tetrodotoxin in Italian Mussels. Is it an Emerging Threat to Humans in the Mediterranean Area?

open access: yes, 2018
Tetrodotoxin (TTX) is one of the most potent neurotoxins, originally found in ovary and liver of pufferfish (Tetraodontidae). Successively, TTX was isolated from many other marine and terrestrial animals, as xanthid crab, trumpet shellfish, blue-ringed ...
Anna Milandri   +9 more
core  

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