Results 111 to 120 of about 25,457 (196)

A Drosophila Mutant with a Temperature-Sensitive Block in Nerve Conduction [PDF]

, 1978
A mutant, napts (no action potential, temperature-sensitive), is described in which axonal conduction fails at high temperature. Synaptic transmission at the larval neuromuscular junction is unimpaired.
Benzer, Seymour, Ganetzky, Barry, Jan, Lily Yeh, Jan, Yuh-Nung, Wu, Chun-Fang   +4 more
core  

Tetrodotoxin: The State-of-the-Art Progress in Characterization, Detection, Biosynthesis, and Transport Enrichment

Marine Drugs
Tetrodotoxin (TTX) is a neurotoxin that binds to sodium channels and blocks sodium conduction. Importantly, TTX has been increasingly detected in edible aquatic organisms.
Xinxin Zhang, Kun Qiao, Ruimin Cui, Min Xu, Shuilin Cai, Qilin Huang, Zhiyu Liu   +6 more
doaj   +1 more source

1. Toxification of pufferfish and transfer of tetrodotoxin (TTX) among TTX-bearing organisms

NIPPON SUISAN GAKKAISHI, 2022
openaire   +1 more source

Proctolin and an Endogenous Proctolin-Like Peptide Enhance the Contractility of the Limulus Heart [PDF]

, 1983
Synthetic proctolin increases the force but not the rate of heart contractions of Limulus in a time- and dose-dependent manner. The threshold of this effect is 3 × 10−10M and the ED50 is approximately 10−8M. At concentrations up to 10−7 M, proctolin has
Augustine, George J., Sullivan, Robert E., Watson, Winsor H., III   +2 more
core   +2 more sources

Neural Coding of Green Flash in Retinal Bipolar Pathways [PDF]

, 2012
What visual information do the graded potentials among retinal bipolar pathways actually transmit from photoreceptors to ganglion cells? The answer does not exist. Even the graded electric signals have not been understood completely.
Caiping Hu
core   +1 more source

Role of Selective α and β Adrenergic Receptor Mechanisms in Rat Jejunal Longitudinal Muscle Contractility [PDF]

, 2018
Gut motility is modulated by adrenergic mechanisms. The aim of our study was to examine mechanisms of selective adrenergic receptors in rat jejunum. Spontaneous contractile activity of longitudinal muscle strips from rat jejunum was measured in 5-ml ...
Balsiger, Bruno, Haefliger, Simon, Rickenbacher, Andreas, Seiler, Roland, Shaw, Sidney   +4 more
core  

Enhanced Adenosine Triphosphate Release From the Urothelium of Patients With Painful Bladder Syndrome:A Possible Pathophysiological Explanation [PDF]

, 2007
Chapple, Christopher R., Chess-Williams, Russell, Kumar, Vivek, Surprenant, Ann Marie   +3 more
core   +1 more source

Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.

The Journal of biological chemistry, 2004
The microO-conotoxins are an intriguing class of conotoxins targeting various voltage-dependent sodium channels and molluscan calcium channels. In the current study, we have shown MrVIA and MrVIB to be the first known peptidic inhibitors of the transient tetrodotoxin-resistant (TTX-R) Na(+) current in rat dorsal root ganglion neurons, in addition to ...
Daly, N., Ekberg, J.A., Thomas, L., Adams, D.J., Lewis, R.J., Craik, D.J.   +5 more
openaire   +2 more sources

The Potential Mechanisms of Althaea rosea (Linn.) Cavan. Flower in Alleviating Tetrodotoxin Poisoning: An Integrated Metabolomics, Network Pharmacology and Experimental Validation

Drug Design, Development and Therapy
Renjin Zheng,1,2 Youjia Wu,1 Lingyi Huang,1 Fanxiang Zeng,3 Liying Huang1 1School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, 350122, People’s Republic of China; 2Physical and Chemical Analysis Department, Fujian Center for Disease Control ...
Zheng R, Wu Y, Huang L, Zeng F, Huang L
doaj  

Scientific opinion: Risks for public health related to the presence of tetrodotoxin (TTX) and TTX analogues in marine bivalves and gastropods

, 2017
Tetrodotoxin (TTX) and its analogues are produced by marine bacteria and have been detected in marine bivalves and gastropods from European waters. The European Commission asked EFSA for a scientific opinion on the risks to public health related to the presence of TTX and TTX analogues in marine bivalves and gastropods. The Panel on Contaminants in the
Knutsen, Helle Katrine, Alexander, Jan, Barregård, Lars, Bignami, Margherita, Brüschweiler, Beat, Ceccatelli, Sandra, Cottrill, Bruce, Dinovi, Michael, Edler, Lutz, Grasl-Kraupp, Bettina, Hogstrand, Christer, Hoogenboom, L.A.P., Nebbia, Carlo Stefano, Oswald, Isabelle P., Rose, Martin, Roudot, Alain-Claude, Schwerdtle, Tanja, Vleminckx, Christiane, Vollmer, Günter, Wallace, Heather, Arnich, Nathalie, Benford, Diane, Botana, Luis, Viviani, Barbara, Arcella, Davide, Binaglia, Marco, Horvath, Zsuzsanna, Steinkellner, Hans, Van Manen, Mathijs, Petersen, Annette   +29 more
openaire   +1 more source