Results 21 to 30 of about 10,876 (160)

The First Data on the Complete Genome of a Tetrodotoxin-Producing Bacterium

open access: yesToxins, 2021
Tetrodotoxin (TTX)-producing bacteria have attracted great interest as a model system for study of the TTX biosynthetic route. Here, we report the complete genome of the TTX-producing bacterium Bacillus sp. 1839.
Daria I. Melnikova   +2 more
doaj   +2 more sources

Confirmation and distribution of tetrodotoxin for the first time in terrestrial invertebrates: two terrestrial flatworm species (Bipalium adventitium and Bipalium kewense). [PDF]

open access: yesPLoS ONE, 2014
The potent neurotoxin tetrodotoxin (TTX) is known from a diverse array of taxa, but is unknown in terrestrial invertebrates. Tetrodotoxin is a low molecular weight compound that acts by blocking voltage-gated sodium channels, inducing paralysis. However,
Amber N Stokes   +7 more
doaj   +3 more sources

Behavioral and Chemical Ecology of Marine Organisms with Respect to Tetrodotoxin [PDF]

open access: yesMarine Drugs, 2010
The behavioral and chemical ecology of marine organisms that possess tetrodotoxin (TTX) has not been comprehensively reviewed in one work to date. The evidence for TTX as an antipredator defense, as venom, as a sex pheromone, and as an attractant for TTX-
Becky L. Williams
doaj   +2 more sources

An improved competitive inhibition enzymatic immunoassay method for tetrodotoxin quantification [PDF]

open access: yesBiological Procedures Online, 2012
Quantifying tetrodotoxin (TTX) has been a challenge in both ecological and medical research due to the cost, time and training required of most quantification techniques.
Stokes Amber N   +2 more
doaj   +3 more sources

Tetrodotoxin Sensitivity of the Vertebrate Cardiac Na+ Current

open access: yesMarine Drugs, 2011
Evolutionary origin and physiological significance of the tetrodotoxin (TTX) resistance of the vertebrate cardiac Na+ current (INa) is still unresolved.
Jaakko Haverinen   +2 more
doaj   +2 more sources

An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults [PDF]

open access: yesJournal of Toxicology, 2018
We investigated the concentration of tetrodotoxin (TTX) in sections of skin containing and lacking red dorsal spots in both Eastern newt (Notophthalmus viridescens) efts and adults.
Mackenzie M. Spicer   +5 more
doaj   +2 more sources

The Structural Basis and Functional Consequences of Interactions Between Tetrodotoxin and Voltage-Gated Sodium Channels

open access: yesMarine Drugs, 2006
: Tetrodotoxin (TTX) is a highly specific blocker of voltage-gated sodium channels. The dissociation constant of block varies with different channel isoforms.
C. Ruben, Shana L. Geffeney
doaj   +2 more sources

First Report of Two Gymnodimines and Two Tetrodotoxin Analogues in Invertebrates from the North Atlantic Coast of Spain

open access: yesMarine Drugs, 2023
Gymnodimine D (GYM D), 16-desmethyl gymnodimine D (16-desmethyl GYM D), and two tetrodotoxin analogues have been found in invertebrates obtained from the north Atlantic coast of Spain from May 2021 to October 2022.
Araceli E. Rossignoli   +3 more
doaj   +1 more source

A Microencapsulation Method for Delivering Tetrodotoxin to Bivalves to Investigate Uptake and Accumulation

open access: yesMarine Drugs, 2021
Most marine biotoxins are produced by microalgae. The neurotoxin tetrodotoxin (TTX) has been reported in many seafood species worldwide but its source is unknown, making accumulation and depuration studies in shellfish difficult.
Laura Biessy   +6 more
doaj   +1 more source

From Poison to Promise: The Evolution of Tetrodotoxin and Its Potential as a Therapeutic

open access: yesToxins, 2021
Tetrodotoxin (TTX) is a potent neurotoxin that was first identified in pufferfish but has since been isolated from an array of taxa that host TTX-producing bacteria.
Gary M. Bucciarelli   +5 more
doaj   +1 more source

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