Results 161 to 170 of about 25,457 (196)

Enhanced Control of Liposomal Drug Release by Drug-Aptamer Complexes. [PDF]

open access: yesAdv Mater
Huang X   +7 more
europepmc   +1 more source
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Inhibition of Tetrodotoxin (TTX)-Resistant and TTX-Sensitive Neuronal Na+ Channels by the Secretolytic Ambroxol

Molecular Pharmacology, 2002
Ambroxol has a long history for the treatment of airway diseases because of its beneficial effects on surfactant synthesis and mucus-modifying properties. Some findings, however, point to an additional effect on neuronal signal transduction: ambroxol can suppress reflexes such as the cough or the corneal reflex.
Thomas, Weiser, Nicola, Wilson
openaire   +2 more sources

SERS study of tetrodotoxin (TTX) by using silver nanoparticle arrays

2009 Conference on Lasers & Electro Optics & The Pacific Rim Conference on Lasers and Electro-Optics, 2009
The optical properties of tetrodotoxin (TTX), a scarce toxin with anesthetic properties, were studied using nanoparticle arrays-assisted surface-enhanced Raman scattering (SERS). The nanoparticles arrays were fabricated using nanosphere lithography and a metallic lift-off process to control the particle size, shape, and spacing in the arrays.
Wen-Chi Lin   +6 more
openaire   +1 more source

Evidence of accumulation of tetrodotoxin (TTX) in tissues and body parts of ectoparasitic copepods via their feeding on mucus of TTX-bearing pufferfish

Toxicon, 2021
Adults of the ectoparasitic copepod Caligus fugu found on tetrodotoxin (TTX)-bearing pufferfish such as Takifugu alboplumbeus and Takifugu flavipterus are known to accumulate TTX in body tissues and parts other than the ovaries, oviducts, eggs, and cuticles.
Tomohisa Kodama   +6 more
openaire   +2 more sources

Construction of a single chain variable fragment antibody (scFv) against tetrodotoxin (TTX) and its interaction with TTX

Toxicon, 2014
Tetrodotoxin (TTX) is a small molecular weight neurotoxin that occludes voltage-gated sodium channels in nerve and muscle tissue, resulting in respiratory paralysis and death. A high affinity antibody that can neutralize the toxicity of TTX is still lacking, so it is very important to prepare an antibody for TTX therapy and detection.
Rongzhi, Wang   +8 more
openaire   +2 more sources

Seafood cross-contamination by tetrodotoxin (TTX): management of an unusual route of exposure

Journal of Consumer Protection and Food Safety, 2023
In this study, liquid chromatography with tandem mass spectroscopy was applied to detect Tetrodotoxin and analogues (TTXs) on pufferfish (Sphoeroides marmoratus) tissues, accidentally found in the stomach of a cuttlefish (Sepia officinalis). The cuttlefish tissues were also analysed.
Tinacci L.   +5 more
openaire   +2 more sources

Ketamine blockage of both tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels of rat dorsal root ganglion neurons

Brain Research Bulletin, 2000
Ketamine, a general anesthetic, has been reported to block sodium channels. Two types of Na(+) channels, tetrodotoxin (TTX)-sensitive (TTX-s) and TTX-resistant (TTX-r), are expressed in dorsal root ganglion (DRG) neurons. The present study was to investigate the effects of ketamine on both types, particularly on TTX-r channels, using whole-cell patch ...
Z S, Zhou, Z Q, Zhao
openaire   +2 more sources

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