Results 11 to 20 of about 2,265 (188)

Real-Life Indirect Case Matched Comparison of Dupilumab and Tezepelumab on Airway Oscillometry. [PDF]

Allergy
Allergy, Volume 81, Issue 1, Page 260-262, January 2026.
Greig R, Chan R, Lipworth B.
europepmc   +4 more sources

Tezepelumab in severe asthma: chest computed tomography assessment of airway remodeling and clinical remission [PDF]

Frontiers in Pharmacology
IntroductionSevere asthma is characterized by persistent uncontrolled symptoms despite optimal standard therapy and/or by the need for high-intensity treatment to maintain control.
Chiara Lupia, Caterina Battaglia, Daniela Pastore, Youngjin Lee, Giovanna Lucia Piazzetta, Emanuela Chiarella, Nadia Lobello, Giovanni Sireno, Alessandro Pullano, Claudia Crimi, Alessandro Vatrella, Francesco Manti, Pier Paolo Arcuri, Domenico Laganà, Girolamo Pelaia, Corrado Pelaia   +15 more
doaj   +2 more sources

Tezepelumab achieves improvement of severe uncontrolled asthma and rhinosinusitis: Case series [PDF]

Journal of Allergy and Clinical Immunology: Global
Tezepelumab, a mAb targeting thymic stromal lymphopoietin (TSLP), reduces exacerbations in severe asthma. Four cases in which patients with severe asthma and chronic rhinosinusitis with nasal polyps showed improvements in both conditions after receiving ...
Shigesato Inoue, MD, Hiroaki Ogata, MD, PhD, Yoichi Dotake, MD, Koichi Takagi, MD, PhD, Ayaka Shiota, MD, Yumiko Ishii, MD, PhD, Kentaro Tanaka, MD, PhD, Keiko Kan-o, MD, PhD, Hiromasa Inoue, MD, PhD   +8 more
doaj   +2 more sources

Case Report: Sequential use of tezepelumab and mepolizumab for eosinophilic otitis media in EGPA: a steroid-sparing strategy [PDF]

Frontiers in Allergy
Even in eosinophilic granulomatosis with polyangiitis (EGPA), not all manifestations of eosinophilic inflammation respond equally to anti–interleukin-5 (IL-5) therapy.
Osamu Matsuno, Masahiro Kawamoto, Tansri Wibowo, Yutaka Ishida, Atsuhsi Ogata   +4 more
doaj   +2 more sources

Biologic Therapies: Targeting Severe Asthma at the Molecular Level [PDF]

Journal of Education, Health and Sport
Introduction: Severe asthma is a chronic respiratory condition that affects a significant number of individuals, causing persistent inflammation of the airways and leading to recurrent symptoms such as wheezing, coughing, and shortness of breath ...
Kamila Szewczyk, Bartłomiej Szewczyk, Wiktoria Julia Krzesłowska, Paulina Pytel, Szymon Wiśniewski, Weronika Hołownia   +5 more
doaj   +3 more sources

Tezepelumab for early-onset severe allergic asthma with persistent airflow limitation and small airway dysfunction: a treatable traits approach [PDF]

Drugs in Context
We report the case of an 18-year-old woman with early-onset severe allergic asthma and no other type 2 biomarkers except the presence of IgE, complicated by persistent airflow limitation, air trapping and forced oscillation technique-defined small airway
Francesco Menzella, Claudio Sorino, Carlo Lombardi, Annamaria Bosi, Silvia Tonin, Lorenzo Corsi, Andrea Ballarin, Marcello Cottini   +7 more
doaj   +2 more sources

COPD 2.0: Bronchodilators, biologics and beyond - A systematic review [PDF]

Lung India
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by persistent airflow limitation and chronic inflammation. Conventional bronchodilators have been the mainstay of therapy; however, their efficacy in certain
Huda Shamim, Anil Kumar Singh, Rahul Sharma, Rajat Kumar Mishra   +3 more
doaj   +2 more sources

Tezepelumab for asthma with current or previous smoking habit: Case series [PDF]

Journal of Allergy and Clinical Immunology: Global
Tezepelumab effectively treated severe asthma in a current smoker and a former smoker, suggesting that thymic stromal lymphopoietin is involved in the pathogenesis of severe asthma in these patients. Tezepelumab may additionally be used for severe asthma
Yoshiro Kai, MD, PhD, Kentaro Suzuki, MD, Ryosuke Kataoka, MD   +2 more
doaj   +2 more sources

The Role of Biologic Therapy Switching to Optimize the Treatment of Severe Pediatric Asthma: Tezepelumab Is a New Therapeutic Alternative for Adolescents [PDF]

Children
Background/Objectives: The emergence of biologic therapies has transformed the management of severe asthma, offering targeted treatments that improve symptom control and reduce exacerbations.
María Erroz Ferrer, Miren Paniagua García, Natividad Viguria Sánchez, Laura Moreno-Galarraga   +3 more
doaj   +2 more sources

Tezepelumab in Adults with Severe Chronic Rhinosinusitis with Nasal Polyps [PDF]

New England Journal of Medicine
BACKGROUND: Treatment with tezepelumab has been effective for sinonasal symptoms in patients with severe, uncontrolled asthma and a history of chronic rhinosinusitis with nasal polyps, but its efficacy and safety in adults with severe, uncontrolled ...
?, ?, Almqvist, Gun, Bahadori, Lila, Chen, Claudia, Desrosiers, Martin, Han, Joseph K., Hellqvist, Åsa, Hopkins, Claire, Jagadeesh, Shankar, Lee, Stella E., Li, Ting, Lipworth, Brian J., MacKay, Jamie, Mankad, Vaishali S., Margolis, Mary Kay, McLaren, Julie, Megally, Ayman, Mullol, Joaquim, Pfaar, Oliver, Ponnarambil, Sandhia S.   +19 more
core   +4 more sources