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Real-life preliminary evidence for basophils as predictors of Tezepelumab response in severe asthma

Expert Review of Clinical Immunology
Background Severe asthma is a complex disease with persistent symptoms despite high-dose inhaled therapy. Tezepelumab, a monoclonal antibody targeting thymic stromal lymphopoietin (TSLP), has shown efficacy across asthma phenotypes.
V. Quaranta   +8 more
semanticscholar   +1 more source

Severe asthma, biologic hypersensitivity and inefficacy: overcoming treatment barriers with tezepelumab

Journal of Asthma
Severe asthma is a heterogeneous disease involving multiple inflammatory pathways, with significant therapeutic challenges. Biologic therapies targeting T2 inflammation improve outcomes but may, in rare cases, trigger hypersensitivity reactions due to ...
Maria Braganca   +4 more
semanticscholar   +1 more source

Tezepelumab: A Potential New Biological Therapy for Severe Refractory Asthma

International Journal of Molecular Sciences, 2021
Alessandro Vatrella   +2 more
exaly  

Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma and Perennial Allergy

Journal of Allergy and Clinical Immunology: in Practice, 2021
Jonathan Corren   +2 more
exaly  

Tezepelumab in the Treatment of Uncontrolled Severe Asthma

Annals of Pharmacotherapy, 2023
Pramodini Kale-Pradhan, Melissa Lipari
exaly  

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