Results 71 to 80 of about 4,308 (211)

Temperature effects from hydropeaking impair egg and larval development in Danube salmon Hucho hucho and brown trout Salmo trutta

open access: yesJournal of Fish Biology, EarlyView.
Abstract Hydropeaking is considered an important stressor for salmonids and other species in rivers affected by hydropower. In this study, we investigated the in situ effects of hydropeaking on the survival of eggs and larvae of fall spawning brown trout as well as spring spawning Danube salmon.
Julius Gorenz   +3 more
wiley   +1 more source

Differences of log absolute bacterial bioburden at visit 7 and visit 4 for TFV, TFV/LNG and placebo IVR users.

open access: yes, 2019
Differences of log absolute bacterial bioburden at visit 7 and visit 4 for TFV, TFV/LNG and placebo IVR users.
Mark A. Marzinke (734979)   +7 more
core   +1 more source

The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: a mechanism of action study

open access: yesRetrovirology, 2009
Background Tenofovir disoproxil fumarate (TDF), emtricitabine (FTC), and efavirenz (EFV) are the three components of the once-daily, single tablet regimen (Atripla) for treatment of HIV-1 infection.
Svarovskaia Evguenia S   +7 more
doaj   +1 more source

Prevotella bivia Influences Antiretroviral Pharmacokinetics and Viral Replication in an Ex Vivo Vaginal Tissue Model

open access: yesClinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT The vaginal microbiome plays a complex role in tenofovir's mucosal pharmacology. While the relative contribution of systemic versus local concentrations to PrEP PK/PD is an ongoing debate, the development of effective HIV prevention requires an understanding of events at the site of transmission.
Alyssa M. Lantz   +4 more
wiley   +1 more source

Poly (I:C) improves the efficacy of TFV in cervical tissues.

open access: yes, 2015
(A) HIV-1 p24 levels (ng/ml) in HIV-1 infected cervical tissues left untreated or treated with TFV at 10 μg/ml alone or in combination with poly (I:C) at 20 μg/ml were evaluated after washing the residual input virus (day 0), and again on days 11 and 21 ...
Sherrill L. Macura (762319)   +5 more
core   +1 more source

Social Representations of Bedside Milk Expression Among Mothers of Preterm Newborns in Neonatal Intensive Care Units

open access: yesJournal of Advanced Nursing, Volume 82, Issue 6, Page 6362-6372, June 2026.
ABSTRACT Aim To understand the social representations of bedside milk expression (BME) among mothers of preterm newborns in neonatal intensive care units (NICUs). Design Qualitative descriptive study. Methods The study was conducted from July to August 2024 in two NICUs of a referral maternity hospital in Fortaleza, Brazil.
Ana Karen de Sousa Alves   +8 more
wiley   +1 more source

Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1205-1215, May 2026.
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco   +17 more
wiley   +1 more source

TFV-DP concentrations among participants by gender and adherence at week 12 and 24.

open access: yes
TFV-DP concentrations among participants by gender and adherence at week 12 and 24.
Yuitiang Durier (17775890)   +11 more
core   +1 more source

Karadeniz Bölgesinde Bulunan İllerin Eğitim Etkinliklerinin Ortaöğretim Düzeyinde İncelenmesi: Malmquıst-TFV Endeksi Uygulaması

open access: yesAnadolu Üniversitesi Sosyal Bilimler Dergisi, 2016
 Hızla gelişen rekabet ortamı içerisinde toplumların gelişimi, eğitimde etkinlik ve verimliliği arttırmalarıyla mümkündür. Bu kapsamda özellikle ortaöğretim, bir ülkenin kalkınmasında önemli rol oynamaktadır. Bu çalışmada Karadeniz Bölgesi’nde bulunan 18 ilin 2007-2011 dönemindeki ortaöğretim düzeyinde eğitim performanslarında meydana ...
AR, Doç. Dr. İlker Murat   +2 more
openaire   +5 more sources

Pharmacokinetics, Pharmacodynamics, Efficacy and Drug Resistance Selection of Injectable Long‐Acting Lenacapavir Pre‐Exposure Prophylaxis (PrEP) Against HIV

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Oral pre‐exposure prophylaxis (PrEP) can substantially reduce HIV infection risk when taken as prescribed. However, many individuals struggle adhering to the daily regimen. Twice‐yearly injections of the novel HIV capsid inhibitor lenacapavir (LEN) demonstrated potential in recent PrEP trials.
Hee‐yeong Kim   +3 more
wiley   +1 more source

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