Results 51 to 60 of about 4,308 (211)
A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study). [PDF]
PLoS ONE, 2015 The CHARM-01 study characterized the safety, acceptability, pharmacokinetics (PK), and pharmacodynamics (PD) of three tenofovir (TFV) gels for rectal application.
Ian Mcgowan +19 more
doaj +1 more source
, 2018 TFV API spectra profile and its corresponding functional peaks in spectra of TFV gel and insert formulations.
Meredith R. Clark (531070) +4 more
core +1 more source
Urine Assay to Measure Tenofovir Concentrations in Patients Taking Tenofovir Alafenamide
Frontiers in Pharmacology, 2020 Background: HIV pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine is effective when taken daily. Previously, we developed a urine assay capable of detecting the prodrug tenofovir (TFV) in patients taking tenofovir disoproxil fumarate (TDF ...
Linden Lalley-Chareczko +6 more
doaj +1 more source
Arthroscopic Repair of the Anterior Root of the Lateral Meniscus Using Knotless All‐Suture Anchors
Arthroscopy Techniques, EarlyView.Abstract Anterior root tears of the lateral meniscus are uncommon but can significantly disrupt knee biomechanics by increasing contact pressures and accelerating cartilage degeneration if left untreated. This article describes an arthroscopic technique for repair of the anterior root of the lateral meniscus using all‐suture anchors.
Tanner Nishioka +6 more
wiley +1 more source
, 2015 Qualitative adherence composite scores, corresponding TFV and TFV-DP concentrations, and estimated doses per interval [7].
Khatija Ahmed (630798) +5 more
core +1 more source
Arthroscopy Techniques, EarlyView.Abstract This technical note describes a knotless trans‐tendon proximal‐pulley repair with distal suture‐bridge fixation and bioinductive collagen patch augmentation for high‐grade partial gluteus medius and minimus tears. The technique preserves intact tendon fibers, restores broad footprint compression, and supports biologic healing through a ...
Maria Agustina Olarán +6 more
wiley +1 more source
Ratio of unphosphorylated TFV to phosphorylated TFV-DP by anatomic sampling sites.
, 2013 Pairs are included if at least one value in the pair is above the limit of assay quantitation and the other is above the limit of assay detection. “N” is the number of pairs available meeting the inclusion criteria above.
Karen Patterson (278030) +13 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Background Female sex hormones used in feminizing hormone therapy (FHT) may influence activation and persistence of HIV pre‐exposure prophylaxis (PrEP) medications. The clinical relevance of this interaction remains unclear, particularly for transgender and cisgender women (TGW and CGW).
Elizabeth Hastie +10 more
wiley +1 more source
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT Despite rapid growth in gender lens investing (GLI), substantial variation remains in how gender lens equity funds (GLEFs) integrate gender equality criteria into investment strategies. We map a universe of 43 GLEFs and develop a framework capturing gender equality screening breadth and accountability depth (fund‐level disclosure and ...
Freyja Vilborg Thorarinsdottir +3 more
wiley +1 more source
Boxplots of TFV and TFV-DP concentrations by anatomic site.
, 2013 Side-by-side boxplots of end-of-period visit data for all participants by anatomic site and dosing regimen are shown. Each box indicates the interquartile range with center bar as median and whiskers 1.5 times the quartile.
Karen Patterson (278030) +13 more
core +1 more source