Results 51 to 60 of about 412 (125)

Chronic Pain as an Early Diagnostic Clue in Hereditary Multiple Exostoses: Two Pediatric Cases Highlighting Diagnostic Delay

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Hereditary multiple exostoses (HME) is a rare autosomal dominant skeletal disorder characterized by the development of multiple osteochondromas adjacent to the growth plates. Although skeletal deformities and palpable masses are common findings, chronic pain may represent an early and underappreciated diagnostic clue, particularly in pediatric
Melissa Mariti Fraga, Valesca Oliveira Paes Tanaka, Luciana Tudech Salgueiro Pedro Paulo, Maria Carolina Santos, Carolina Costa Figueiredo, Nara Michelle de Araújo Evangelista, Vânia de Fátima Tonetto Fernandes, Guido de Paula Colares Neto   +7 more
wiley   +1 more source

İşletmelerin Malmquist-TFV Endeksi İle Verimliliklerinin Analizi: Tekstil Sanayi Örneği

Selçuk Üniversitesi Sosyal Bilimler Meslek Yüksekokulu Dergisi, 2018
ÖZ       Günümüzde işletmelerin rekabetçi üstünlük ve ortalamanın üzerinde getiri elde etmelerinde göstermiş oldukları performans, önem arz etmektedir. İşletmelerin performansını belirleyen en önemli ölçütlerden birisi verimlilik artışıdır. Verimlilik artışıyla işletmelerin amaçlarına ulaşabilmeleri ve kârlılık hedeflerini tutturabilmeleri mümkün hale
GELMEZ, Emel, GÖRAL, Ramazan, ÇAĞLIYAN, Vural   +2 more
openaire   +4 more sources

Renal function in African women receiving tenofovir disoproxil fumarate as pre‐exposure prophylaxis for HIV during pregnancy and postpartum: A postpartum safety analysis in the CAP016 randomized control trial

HIV Medicine, Volume 27, Issue 8, Page 1333-1343, August 2026.
Abstract Background The effect of tenofovir disoproxil fumarate (TDF) when used as pre‐exposure prophylaxis (PrEP) on renal function in pregnant and postpartum women is understudied. An open‐label clinical trial (CAP016 study) was designed to examine the safety of TDF‐PrEP use during pregnancy and breastfeeding.
Gaysheen Kistan, Tonya Esterhuizen, Megeshinee Naidoo, Alicia C. Desmond, Motshedisi Sebitloane, Dhayendre Moodley   +5 more
wiley   +1 more source

Using Tenofovir Diphosphate Levels to Evaluate Factors Associated With PrEP Non‐Adherence and Performance of Indirect Adherence Measures in Latin America: A Prospective, Single‐Arm, Open‐Label, Multicentre Implementation Study (ImPrEP)

Journal of the International AIDS Society, Volume 29, Issue S3, July 2026.
ABSTRACT Introduction Tenofovir‐based oral pre‐exposure prophylaxis (PrEP) is pivotal for HIV prevention in Latin America. Monitoring PrEP adherence is crucial for maximizing its impact and identifying individuals who may benefit from additional support.
Thiago S. Torres, Mayara Secco Torres Silva, Brenda Hoagland, Luana Monteiro Spindola Marins, Carolina Coutinho, Emilia M. Jalil, Pedro Leite, Marcelo Cunha, Ronaldo Moreira, Iuri C. Leite, Kelika Konda, Juan Guanira, Marcos Benedetti, Cristina Pimenta, Hamid Vega‐Ramirez, Sandra W. Cardoso, Carlos F. Caceres, Peter L. Anderson, Beatriz Grinsztejn, Valdilea G. Veloso, for ImPrEP Study Group   +20 more
wiley   +1 more source

Trapped Fourth Ventricle in a Pediatric Patient With a History of Post‐Traumatic Hydrocephalus and Ventriculoperitoneal Shunt: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Trapped fourth ventricle (TFV) is a rare, serious complication of ventriculoperitoneal (VP) shunting that can mimic posterior fossa tumors and cause life‐threatening brainstem compression. We report the case of a 7‐year‐old boy with a history of a VP shunt for post‐traumatic hydrocephalus who presented with progressive drowsiness and gait ...
Muhammad Hamza, Muhammad Ibrahim, Ihsan Ullah, Rehmat Farhaj, Fazeela Bibi, Khalil El Abdi, Bilal Aslam, Vohra Maham Hassan, Said Hamid Sadat   +8 more
wiley   +1 more source

Prevotella bivia Influences Antiretroviral Pharmacokinetics and Viral Replication in an Ex Vivo Vaginal Tissue Model

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT The vaginal microbiome plays a complex role in tenofovir's mucosal pharmacology. While the relative contribution of systemic versus local concentrations to PrEP PK/PD is an ongoing debate, the development of effective HIV prevention requires an understanding of events at the site of transmission.
Alyssa M. Lantz, Lindsey B. Collins, Elizabeth B. Hirsch, Christopher Staley, Melanie R. Nicol   +4 more
wiley   +1 more source

Karadeniz Bölgesinde Bulunan İllerin Eğitim Etkinliklerinin Ortaöğretim Düzeyinde İncelenmesi: Malmquıst-TFV Endeksi Uygulaması

Anadolu Üniversitesi Sosyal Bilimler Dergisi, 2016
 Hızla gelişen rekabet ortamı içerisinde toplumların gelişimi, eğitimde etkinlik ve verimliliği arttırmalarıyla mümkündür. Bu kapsamda özellikle ortaöğretim, bir ülkenin kalkınmasında önemli rol oynamaktadır. Bu çalışmada Karadeniz Bölgesi’nde bulunan 18 ilin 2007-2011 dönemindeki ortaöğretim düzeyinde eğitim performanslarında meydana ...
AR, Doç. Dr. İlker Murat, OFLUOĞLU, Öğr. Grv. Aylin, BAKİ, Prof. Dr. Birdoğan   +2 more
openaire   +5 more sources

Social Representations of Bedside Milk Expression Among Mothers of Preterm Newborns in Neonatal Intensive Care Units

Journal of Advanced Nursing, Volume 82, Issue 6, Page 6362-6372, June 2026.
ABSTRACT Aim To understand the social representations of bedside milk expression (BME) among mothers of preterm newborns in neonatal intensive care units (NICUs). Design Qualitative descriptive study. Methods The study was conducted from July to August 2024 in two NICUs of a referral maternity hospital in Fortaleza, Brazil.
Ana Karen de Sousa Alves, Ana Paula Melo Façanha, Elaine Meireles Castro, Keline Soraya Santana Nobre, Flávia Vasconcelos Teixeira, Maria Milena Farias de Souza Castro, José Mateus Pires, Victórya Suéllen Maciel Abreu, Priscila de Souza Aquino   +8 more
wiley   +1 more source

Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1205-1215, May 2026.
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco, Troy D. Wood, Raymond Cha, Jill S. Hochreiter, Susan L. Rosenkranz, Mona Farhad, Kyle R. Whitson, Connor E. Gould, Lauren E. Hill, Linda L. Hale, Philip H. Lindhorst, Diala Ghazal, Charlene R. Taylor, Madiha Quraishi, Suzanne M. Siminski, Yoninah Cramer, Heather L. Sprenger, Gene D. Morse   +17 more
wiley   +1 more source

Pharmacokinetics, Pharmacodynamics, Efficacy and Drug Resistance Selection of Injectable Long‐Acting Lenacapavir Pre‐Exposure Prophylaxis (PrEP) Against HIV

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Oral pre‐exposure prophylaxis (PrEP) can substantially reduce HIV infection risk when taken as prescribed. However, many individuals struggle adhering to the daily regimen. Twice‐yearly injections of the novel HIV capsid inhibitor lenacapavir (LEN) demonstrated potential in recent PrEP trials.
Hee‐yeong Kim, Antonia Liebenberg, Lanxin Zhang, Max von Kleist   +3 more
wiley   +1 more source