Results 41 to 50 of about 3,329 (168)

Urine Assay to Measure Tenofovir Concentrations in Patients Taking Tenofovir Alafenamide

open access: yesFrontiers in Pharmacology, 2020
Background: HIV pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine is effective when taken daily. Previously, we developed a urine assay capable of detecting the prodrug tenofovir (TFV) in patients taking tenofovir disoproxil fumarate (TDF ...
Linden Lalley-Chareczko   +6 more
doaj   +1 more source

Improved pharmacokinetics of tenofovir ester prodrugs strengthened the inhibition of HBV replication and the rebalance of hepatocellular metabolism in preclinical models

open access: yesFrontiers in Pharmacology, 2022
Tenofovir (TFV) ester prodrugs, a class of nucleotide analogs (NAs), are the first-line clinical anti-hepatitis B virus (HBV) drugs with potent antiviral efficacy, low resistance rate and high safety.
Xiaodan Hong   +6 more
doaj   +1 more source

Study of Damage to Shutters Exposed to a Vegetation Fire: Definition of Vulnerability Thresholds

open access: yesFire and Materials, EarlyView.
ABSTRACT This study examines the fire behavior of wooden, PVC, and aluminum shutters through laboratory and large‐scale experiments. Laboratory tests were conducted using a cone calorimeter to assess the ignitability of the PVC and wooden shutters, focusing on the critical heat flux of ignition, ignition time and critical Flux Time Product (FTP ...
C. Luciani   +5 more
wiley   +1 more source

Türkiye Tarım Sektöründe Toplam Faktör Verimliliği (TFV): 1961-2021 Döneminin Malmquist TFV Endeksiyle Analizi

open access: yesVerimlilik Dergisi
Amaç: Bu çalışma, Türkiye tarım sektörünün 1961–2021 dönemindeki toplam faktör verimliliğini (TFV) ölçmek, teknik etkinlik değişimi (TEC) ile teknolojik etkinlik değişimi (TC) gibi TFV bileşenlerinin zaman içinde gösterdiği performansı etkileyen faktörleri analiz etmek amacıyla gerçekleştirilmiştir.
Mehmet Ali Cevheri, Nihat Küçük
openaire   +1 more source

The evolution of the importance of the true and fair view (TFV) principle. The case of Poland [PDF]

open access: yesFinancial Sciences, 2018
The aim of this paper is to analyse matters of truth, which is inherent issue of accounting (and therefore in reporting, as its part), which is reflected in the true and fair principle (TFV). The paper demonstrates the essence of the TFV principle and the evolution of its role and place among the set of qualitative characteristics of financial ...
openaire   +1 more source

Brain viral reservoir seeding and neurological metabolic dysregulation in early‐life immunodeficiency virus infection

open access: yesBrain Pathology, EarlyView.
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma   +12 more
wiley   +1 more source

Detection and quantification of antiviral drug tenofovir using silver nanoparticles and surface enhanced Raman spectroscopy (SERS) with spatially resolved hotspot selection

open access: yesFrontiers in Nanotechnology, 2023
This study introduces a convenient and ultra-sensitive method of detection and quantification of the antiviral drug, tenofovir (TFV), by surface-enhanced Raman spectroscopy (SERS).
Marguerite R. Butler   +7 more
doaj   +1 more source

Gender Lens Equity Funds: A Methodological Breadth–Accountability Depth Framework and Observed Outcomes

open access: yesCorporate Social Responsibility and Environmental Management, Volume 33, Issue 5, Page 6977-6999, September 2026.
ABSTRACT Despite rapid growth in gender lens investing (GLI), substantial variation remains in how gender lens equity funds (GLEFs) integrate gender equality criteria into investment strategies. We map a universe of 43 GLEFs and develop a framework capturing gender equality screening breadth and accountability depth (fund‐level disclosure and ...
Freyja Vilborg Thorarinsdottir   +3 more
wiley   +1 more source

A multi-compartment, single and multiple dose pharmacokinetic study of the vaginal candidate microbicide 1% tenofovir gel. [PDF]

open access: yesPLoS ONE, 2011
Tenofovir (TFV) gel is being evaluated as a microbicide with pericoital and daily regimens. To inhibit viral replication locally, an adequate concentration in the genital tract is critical.Forty-nine participants entered a two-phase study: single-dose ...
Jill L Schwartz   +6 more
doaj   +1 more source

Comparing Tear Film Viscosity between Sjögren and Non-Sjögren Dry Eye Disease

open access: yesLife, 2023
This study aimed to compare tear film viscosity (TFV) in Sjögren and non-Sjögren dry eye diseases (DEDs). This was a cross-sectional observational study.
Hung-Yin Lai   +4 more
doaj   +1 more source

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