Results 21 to 30 of about 3,329 (168)

Evaluation of Rapidly Disintegrating Vaginal Tablets of Tenofovir, Emtricitabine and Their Combination for HIV-1 Prevention

Pharmaceutics, 2014
Vaginal tablets are being developed as an alternative to gels as an inexpensive, discreet dosage form for the administration of microbicides. This work describes the pharmacokinetic (PK) evaluation of rapidly disintegrating vaginal tablets containing ...
Meredith R. Clark, M. Melissa Peet, Sarah Davis, Gustavo F. Doncel, David R. Friend   +4 more
doaj   +1 more source

Living windbreak design for wind erosion control in arid regions: A case study in Dehloran, Iran [PDF]

Desert, 2019
Wind erosion is considered as one of the main processes of land degradation in different parts of the world. Among the most effective ways to control wind erosion is to cover land surface with natural vegetation area.
M. Mirhasani, N. Rostami, M. Bazgir, M. Tavakoli   +3 more
doaj   +1 more source

Renal function in African women receiving tenofovir disoproxil fumarate as pre-exposure prophylaxis for HIV during pregnancy and postpartum: A postpartum safety analysis in the CAP016 randomized control trial. [PDF]

HIV Med
Abstract Background The effect of tenofovir disoproxil fumarate (TDF) when used as pre‐exposure prophylaxis (PrEP) on renal function in pregnant and postpartum women is understudied. An open‐label clinical trial (CAP016 study) was designed to examine the safety of TDF‐PrEP use during pregnancy and breastfeeding.
Kistan G, Esterhuizen T, Naidoo M, Desmond AC, Sebitloane M, Moodley D.   +5 more
europepmc   +2 more sources

Precision or Paradox? AI-Driven Adiposity Imaging in Women With Overweight and Obesity: A Systematic Review and Meta-Analysis. [PDF]

Obes Rev
ABSTRACT Artificial intelligence (AI) enables automated, high‐throughput adiposity quantification, offering refined risk stratification for women with overweight and obesity. We systematically reviewed and meta‐analyzed studies evaluating AI‐based segmentation of visceral, subcutaneous, and total fat in adult women populations (BMI: 25–29.9 and ≥ 30 kg/
Taddese AA, Tam BT.
europepmc   +2 more sources

Benchmarking of productivity of international tourism destinations with Malmquist-TFV index

Journal of Tourism Theory and Research, 2018
Son yıllarda turizm sektöründe mikro düzeyde verimlilik ve etkinlik ölçümü önemli bir araştırma konusu olmasına rağmen, makro düzeyde çok az araştırma bulunmaktadır. Bu nedenle çalışmada uluslararası turizm destinasyonlarının turizm sektörü etkinliğini ve verimliliğini karşılaştırmak, bunun için bir metodoloji oluşturmak amaçlanmaktadır.
GÖRAL, Ramazan, UYGUR, Akyay
openaire   +3 more sources

Sex hormones regulate tenofovir-diphosphate in female reproductive tract cells in culture.

PLoS ONE, 2014
The conflicting results of recent pre-exposure prophylaxis (PrEP) trials utilizing tenofovir (TFV) to prevent HIV infection in women led us to evaluate the accumulation of intracellular TFV-diphosphate (TFV-DP) in cells from the female reproductive tract
Zheng Shen, John V Fahey, Jack E Bodwell, Marta Rodriguez-Garcia, Angela D M Kashuba, Charles R Wira   +5 more
doaj   +1 more source

Model Linking Plasma and Intracellular Tenofovir/Emtricitabine with Deoxynucleoside Triphosphates. [PDF]

PLoS ONE, 2016
The coformulation of the nucleos(t)ide analogs (NA) tenofovir (TFV) disoproxil fumarate (TDF) and emtricitabine (FTC) is approved for HIV-infection treatment and prevention. Plasma TFV and FTC undergo complicated hybrid processes to form, accumulate, and
Xinhui Chen, Sharon M Seifert, Jose R Castillo-Mancilla, Lane R Bushman, Jia-Hua Zheng, Jennifer J Kiser, Samantha MaWhinney, Peter L Anderson   +7 more
doaj   +1 more source

PCM-TV-TFV: A Novel Two-Stage Framework for Image Reconstruction from Fourier Data [PDF]

SIAM Journal on Imaging Sciences, 2017
We propose in this paper a novel two-stage Projection Correction Modeling (PCM) framework for image reconstruction from (non-uniform) Fourier measurements. PCM consists of a projection stage (P-stage) motivated by the multi-scale Galerkin method and a correction stage (C-stage) with an edge guided regularity fusing together the advantages of total ...
Weihong Guo, Guohui Song, Yue Zhang 0036
openaire   +3 more sources

Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal rings in women.

PLoS ONE, 2018
To prevent the global health burdens of human immunodeficiency virus [HIV] and unintended/mistimed pregnancies, we developed an intravaginal ring [IVR] that delivers tenofovir [TFV] at ~10mg/day alone or with levonorgestrel [LNG] at ~20μg/day for 90 days.
Andrea Ries Thurman, Jill L Schwartz, Vivian Brache, Meredith R Clark, Timothy McCormick, Neelima Chandra, Mark A Marzinke, Frank Z Stanczyk, Charlene S Dezzutti, Sharon L Hillier, Betsy C Herold, Raina Fichorova, Susana N Asin, Christiane Rollenhagen, Debra Weiner, Patrick Kiser, Gustavo F Doncel   +16 more
doaj   +1 more source

Diagnostic accuracy of a point‐of‐care urine tenofovir assay, and associations with HIV viraemia and drug resistance among people receiving dolutegravir and efavirenz‐based antiretroviral therapy

Journal of the International AIDS Society, 2023
Introduction Novel point‐of‐care assays which measure urine tenofovir (TFV) concentrations may have a role in improving adherence monitoring for people living with HIV (PLHIV) receiving antiretroviral therapy (ART).
Jienchi Dorward, Richard Lessells, Katya Govender, Pravi Moodley, Natasha Samsunder, Yukteshwar Sookrajh, Phil Turner, Christopher C. Butler, Gail Hayward, Monica Gandhi, Paul K. Drain, Nigel Garrett   +11 more
doaj   +1 more source