Pediatric Trapped Fourth Ventricle: The Need for Objective Surgical-Selection Criteria and Long-Term Surveillance After Open Fenestration. [PDF]
ABSTRACT Open fenestration can be an effective treatment for pediatric trapped fourth ventricle, but case reports should move beyond successful short‐term decompression. Future reports should include objective surgical‐selection criteria, intraoperative confirmation of adhesions, standardized imaging metrics, and long‐term surveillance end points to ...
Awan MA, Raza HU.
europepmc +2 more sources
Predicting Oral HIV Pre-Exposure Prophylaxis Efficacy in Cisgender Women Across Pregnancy and Postpartum. [PDF]
Abstract Cisgender women face an increased risk of HIV acquisition during pregnancy and postpartum. Oral pre‐exposure prophylaxis (PrEP) with emtricitabine and tenofovir disoproxil fumarate (F/TDF) is recommended in pregnancy despite limited published pharmacokinetic (PK) and efficacy data during pregnancy.
Yu Y +17 more
europepmc +2 more sources
Using Tenofovir Diphosphate Levels to Evaluate Factors Associated With PrEP Non-Adherence and Performance of Indirect Adherence Measures in Latin America: A Prospective, Single-Arm, Open-Label, Multicentre Implementation Study (ImPrEP). [PDF]
ABSTRACT Introduction Tenofovir‐based oral pre‐exposure prophylaxis (PrEP) is pivotal for HIV prevention in Latin America. Monitoring PrEP adherence is crucial for maximizing its impact and identifying individuals who may benefit from additional support.
Torres TS +20 more
europepmc +2 more sources
Trapped Fourth Ventricle in a Pediatric Patient With a History of Post-Traumatic Hydrocephalus and Ventriculoperitoneal Shunt: A Case Report and Literature Review. [PDF]
ABSTRACT Trapped fourth ventricle (TFV) is a rare, serious complication of ventriculoperitoneal (VP) shunting that can mimic posterior fossa tumors and cause life‐threatening brainstem compression. We report the case of a 7‐year‐old boy with a history of a VP shunt for post‐traumatic hydrocephalus who presented with progressive drowsiness and gait ...
Hamza M +8 more
europepmc +2 more sources
PrEP at the site of action in cisgender and transgender women: A pharmacology study of blood and rectal CD4<sup>+</sup> lymphocytes. [PDF]
Background Female sex hormones used in feminizing hormone therapy (FHT) may influence activation and persistence of HIV pre‐exposure prophylaxis (PrEP) medications. The clinical relevance of this interaction remains unclear, particularly for transgender and cisgender women (TGW and CGW).
Hastie E +10 more
europepmc +2 more sources
Giresun’daki Fındık Fabrikalarının Etkinlik Analizi: Malmquist - TFV Endeksi Uygulaması [PDF]
Bu calismanin amaci 2006–2012 donemi icin Giresun’daki findik fabrikalarinin performanslarini incelemektir. Belirlenen donemler icin her bir fabrikanin Toplam Faktor Verimliligindeki degisim, Malmquist- Toplam Faktor Verimliligi Endeksi yontemi kullanilarak incelenmistir.
Doğan, Hatice, Bulut, Yetkin
openaire +3 more sources
Towards truer and fairer. The Judgment and Decision-Making research journey through accounting paradigms [PDF]
The aim: The aim of this paper is to integrate different perspectives regarding the true and fair view (TFV) using the accounting paradigms proposed by Chua (1986).
Nelli Artienwicz
doaj +1 more source
K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism. [PDF]
HIV-1 carrying the "Q151M complex" reverse transcriptase (RT) mutations (A62V/V75I/F77L/F116Y/Q151M, or Q151Mc) is resistant to many FDA-approved nucleoside RT inhibitors (NRTIs), but has been considered susceptible to tenofovir disoproxil fumarate (TFV ...
Atsuko Hachiya +8 more
doaj +1 more source
A multi-compartment single and multiple dose pharmacokinetic comparison of rectally applied tenofovir 1% gel and oral tenofovir disoproxil fumarate. [PDF]
This Phase 1, randomized, two-site (United States), double-blind, placebo-controlled study enrolled 18 sexually abstinent men and women. All received a single 300-mg dose of oral tenofovir disoproxil fumarate (TDF) and were then randomized 2:1 to receive
Kuo-Hsiung Yang +10 more
doaj +1 more source
TÜRK SİVİL HAVA TAŞIMACILIĞI ENDÜSTRİSİNİN REKABET GÜCÜNÜN DEĞERLENDİRİLMESİ
Küreselleşen dünyada serbestleşme sürecinin etkisiyle sivil hava taşımacılığı endüstrisinde önemli gelişmeler yaşanmıştır. Serbestleşme sürecinin havayolu işletmelerinde önemli yapısal dönüşümlere sebep olmasına rağmen, dünyada ve özellikle Türkiye’de bu
Ebül Muhsin Doğan, Murat Ahmet Doğan
doaj +1 more source

