Results 101 to 110 of about 8,934 (195)

Parental occupations at birth and risk of adult testicular germ cell tumors in offspring: a French nationwide case–control study

Frontiers in Public Health
BackgroundTesticular germ cell tumors (TGCT) are the most frequent cancer in young men in developed countries. Parental occupational exposures during early-life periods are suspected to increase TGCT risk.
Adèle Paul, Adèle Paul, Aurélie M. N. Danjou, Floriane Deygas, Floriane Deygas, Margot Guth, Astrid Coste, Astrid Coste, Marie Lefevre, Brigitte Dananché, Hans Kromhout, Johan Spinosi, Johan Spinosi, Rémi Béranger, Olivia Pérol, Helen Boyle, Christel Hersant, Vanessa Loup-Cabaniols, Ségolène Veau, Louis Bujan, Louis Bujan, Ann Olsson, Joachim Schüz, Béatrice Fervers, Béatrice Fervers, Barbara Charbotel, Barbara Charbotel   +26 more
doaj   +1 more source

Animal models of TGCT and correlation to human histologic subtypes.

, 2013
TGCTs appear to arise from embryonic germ cells (EGC) in infants and young children (“type I”) or in adolescents and young adults (“type II”) [4]. (For clarity, the presumed carcinoma in situ precursor cell for type II tumours is omitted).
James F. Amatruda (79531), Kenneth S. Chen (401580)   +1 more
core   +1 more source

Comprehensive characterization of cancer‐testis genes in testicular germ cell tumor

Cancer Medicine, 2019
Cancer‐testis (CT) genes are a group of genes restrictedly expressed in testis and multiple cancers and can serve as candidate driver genes participating in the development of cancers.
Yuting Chang, Xuewei Wang, Yide Xu, Liu Yang, Qufei Qian, Sihan Ju, Yao Chen, Shuaizhou Chen, Na Qin, Zijian Ma, Juncheng Dai, Hongxia Ma, Guangfu Jin, Erbao Zhang, Cheng Wang, Zhibin Hu   +15 more
doaj   +1 more source

MicroRNA-371–373 cluster extracellular vesicle-based communication in testicular germ cell tumors

Cell Communication and Signaling
Testicular germ cell tumors (TGCTs) represent the most common type of cancer in young adults. The cluster of microRNAs 371–373 is highly upregulated in TGCTs, and detection of miR-371a-3p specifically is currently being developed for clinical ...
Nuno Tiago Tavares, Catarina Lourenço, Vera Constâncio, Fernanda Fernandes-Pontes, Diana Fonseca, Rui Silva-Santos, Isaac Braga, Joaquina Maurício, Rui Henrique, Michelle Liu, Robert S. Weiss, Aditya Bagrodia, Carmen Jerónimo, João Lobo   +13 more
doaj   +1 more source

Phosphoribosyl transferase domain containing 1: A prognostic biomarker in testicular germ cell tumors

Molecular Therapy: Oncology
Due to the heterogeneity and complex classification of testicular germ cell tumors (TGCTs), prognostic evaluation and therapeutic targets remain unclear.
Peisheng Huang, Yihao Chen, Yongcheng Shi, Chuanfan Zhong, Huawei Lin, Xiaoxue Yu, Kai Chen, Zhuoya Huang, Le Zhang, Shumin Fang, Jianming Lu, Jiahong Chen   +11 more
doaj   +1 more source

Gene-expression signatures as prognostic for relapse in stage I testicular germ cell tumors (TGCT).

, 2016
493 Background: Genomic signatures may compliment pathological features in identifying appropriate patients who may benefit from adjuvant therapy in Stage I (SI) TGCT.
Robert James Hamilton, Padraig Richard Warde, Joan Sweet, Malcolm J. Moore, Neil Winegarden, Aaron Richard Hansen, Jeremy Howard Lewin, Michael A.S. Jewett, Philippe L. Bedard, Carl Virtanen, Benjamin Haibe-Kains, Peter W. M. Chung, Lynn Anson-Cartwright   +12 more
core   +1 more source

Tenosynovial Giant Cell Tumor: Incidence, Prevalence, Patient Characteristics, and Recurrence. A Registry-based Cohort Study in Denmark

, 2017
Objective.Tenosynovial giant cell tumor (TGCT) is a rare benign proliferative and inflammatory disease arising from synovia of joints, bursae, or tendon sheaths.
John F. Acquavella, Robert Sikorski, Ibrahim Qazi, Alma B. Pedersen, Vera Ehrenstein, Søren L. Andersen, Neil Sankar   +6 more
core   +1 more source

Origin and evolution of TGCTs [PDF]

Nature Reviews Urology, 2016
openaire   +1 more source

PD-L1: a promising target for TGCTs [PDF]

Nature Reviews Urology, 2015
openaire   +1 more source

c-MET activated pathways and their implication in TGCTs oncogenesis

, 2020
HGF/C-MET system has a very intricate signalling whose importance is well known during embryogenesis. c-MET de-regulation is widely described in several human cancers, and for this purpose, it is used as a target in several personalized therapies (www.vai.org/met). Though, few data are present in literature about this system in TGCTs.
openaire   +1 more source