Results 151 to 160 of about 8,934 (195)

Open synovectomy for treatment of tenosynovial giant cell tumors of the knee in children. [PDF]

open access: yesJ Surg Case Rep
Georgiev H   +5 more
europepmc   +1 more source

Metabolic profile and skeletal muscle as predictors of survival in testicular germ cell tumors. [PDF]

open access: yesOncologist
Barrón-Hernández A   +9 more
europepmc   +1 more source

Seminal Fluid Biomarkers for Early Cancer Detection: A Systematic Review. [PDF]

open access: yesBiomedicines
Sagitova GR   +6 more
europepmc   +1 more source

Large-scale Sequencing of Testicular Germ Cell Tumour (TGCT) Cases Excludes Major TGCT Predisposition Gene

open access: yesEuropean Urology, 2018
Testicular germ cell tumour (TGCT), the most common cancer in young men, has a significant heritable basis that has long raised questions as to the existence of underlying major high-penetrance susceptibility gene(s). To determine the contribution of rare gene mutations to the inherited risk of TGCT, we analysed germline whole-exome data for 919 TGCT ...
Max Levy   +2 more
exaly   +11 more sources

The utility of cfDNA in TGCT patient management: a systematic review

open access: yesTherapeutic Advances in Medical Oncology, 2022
Background: Testicular germ cell tumors (TGCTs) are the most common young male malignancy with a steadily rising incidence. Standard clinical practice is radical orchidectomy of suspicious lumps followed by histopathological diagnosis and tumor subtyping.
Tomislav Kulis   +2 more
exaly   +8 more sources

Neonatal Hormone Concentrations and Risk of Testicular Germ Cell Tumors (TGCT) [PDF]

open access: yesCancer Epidemiology Biomarkers and Prevention, 2018
Abstract Background: Testicular germ cell tumor (TGCT) incidence has increased over the last 40 years in the United States. In contrast to TGCT among infants, it is hypothesized that TGCT in adolescents and young men is the result of sex steroid hormone imbalance during early fetal development. However, little is known about the neonatal
Xiaomei Ma   +2 more
exaly   +7 more sources

Breaking the Mold: Epigenetics and Genomics Approaches Addressing Novel Treatments and Chemoresponse in TGCT Patients

open access: yesInternational Journal of Molecular Sciences, 2023
Testicular germ-cell tumors (TGCT) have been widely recognized for their outstanding survival rates, commonly attributed to their high sensitivity to cisplatin-based therapies. Despite this, a subset of patients develops cisplatin resistance, for whom additional therapeutic options are unsuccessful, and ~20% of them will die from disease progression at
Rodrigo González-Barrios   +2 more
exaly   +4 more sources

Best clinical management of tenosynovial giant cell tumour (TGCT): A consensus paper from the community of experts [PDF]

open access: yesCancer Treatment Reviews, 2023
: Tenosynovial giant cell tumour (TGCT) is a rare, locally aggressive, mesenchymal tumor arising from the joints, bursa and tendon sheaths. TGCT comprises a nodular- and a diffuse-type, with the former exhibiting mostly indolent course and the latter a ...
Giacomo Giulio Baldi
exaly   +2 more sources

Nontesticular cancers in relatives of testicular germ cell tumor (TGCT) patients from multiple-case TGCT families

open access: yesCancer Medicine, 2015
AbstractTesticular germ cell tumors (TGCT) exhibit striking familial aggregation that remains incompletely explained. To improve the phenotypic definition of familial TGCT (FTGCT), we studied an international cohort of multiple‐case TGCT families to determine whether first‐degree relatives of FTGCT cases are at increased risk of other types of cancer ...
Philip S. Rosenberg   +2 more
exaly   +3 more sources

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