Results 111 to 120 of about 13,537 (210)

Integrated Metabolomic and transcriptomic analyses reveal deoxycholic acid promotes transmissible gastroenteritis virus infection by inhibiting phosphorylation of NF-κB and STAT3

BMC Genomics
Background Acute diarrhea, dehydration and death in piglets are all symptoms of transmissible gastroenteritis virus (TGEV), which results in significant financial losses in the pig industry. It is important to understand the pathogenesis and identify new
Yajing Zhou, Chao Xu, Shanshen Gu, Yeyi Xiao, Shenglong Wu, Haifei Wang, Wenbin Bao   +6 more
doaj   +1 more source

Optimization of the IPMA method for TGEV detection.

, 2016
(A) Purification of mAb 5E8 IgG, Lane 1: protein marker, Lanes 2 and 3: purified IgG. (B) IPMA method for TGEV detection in PK-15 cells using purified IgG. Bar, 50 μm.
Jianfei Chen (3186999), Xin Zhang (35492), Xin Zhao (71840), Hui Dong (153701), Yunnuan Zhu (3186996), Hongyan Shi (1988656), Da Shi (1455439), Li Feng (77923)   +7 more
core   +1 more source

Effect of miR-17 on Polygonum Cillinerve polysaccharide against transmissible gastroenteritis virus

Frontiers in Veterinary Science
Transmissible gastroenteritis virus (TGEV) could cause diarrhea, vomiting, dehydration and even death in piglets, miRNA played an important role in the interaction between virus and cell.
Xueqin Duan, Mengxin Xu, Yunying Wang, Nishang Liu, Xingchen Wang, Yingqiu Liu, Weimin Zhang, Wuren Ma, Lin Ma, Yunpeng Fan   +9 more
doaj   +1 more source

Location of an identified epitope in a predicted structure of the TGEV N protein CTD.

, 2016
The location of the epitope (aa 246–257, shown in red) for mAb 3D7 in the TGEV N protein CTD is highlighted.
Jianfei Chen (3186999), Xin Zhang (35492), Xin Zhao (71840), Hui Dong (153701), Yunnuan Zhu (3186996), Hongyan Shi (1988656), Da Shi (1455439), Li Feng (77923)   +7 more
core   +1 more source

Targeting Coronaviral Replication and Cellular JAK2 Mediated Dominant NF-κB Activation for Comprehensive and Ultimate Inhibition of Coronaviral Activity

Scientific Reports, 2017
Tylophorine-based compounds exert broad spectral, potent inhibition of coronaviruses. NF-κB activation is a common pro-inflammatory response of host cells to viral infection.
Cheng-Wei Yang, Yue-Zhi Lee, Hsing-Yu Hsu, Chuan Shih, Yu-Sheng Chao, Hwan-You Chang, Shiow-Ju Lee   +6 more
doaj   +1 more source

Differentially expressed miRNAs directly targeted the 3' UTR or 5' UTR of the TGEV genome.

, 2015
ssc-miR-28–3p, ssc-miR-126–5p and ssc-miR-30b-5p target the 3' UTR of the TGEV genome (28297 bp–28571 bp), ssc-miR-2411 target the 5' UTR of the TGEV genome (1 bp–303 bp).
Xiao Liu (65413), Ling Zhu (56356), Zhiwen Xu (28724), Yuancheng Zhou (418902), Shan Liao (418901)   +4 more
core   +1 more source

Transmissible gastroenteritis virus (TGEV)-based vectors with engineered murine tropism express the rotavirus VP7 protein and immunize mice against rotavirus

, 2011
A coronavirus vector based on the genome of the porcine transmissible gastroenteritis virus (TGEV) expressing the rotavirus VP7 protein was constructed to immunize and protect against rotavirus infections in a murine model.
Ribes, Juan Manuel, Luis Enjuanes, Buesa, Javier, Montava, Rebeca, Javier Ortego, Juan Ceriani, Rebeca Montava, Javier Buesa, Ortego, Javier, Juan Manuel Ribes, Ceriani, Juan Eduardo, Enjuanes Sánchez, Luis   +11 more
core   +1 more source

Morphological changes in TGEV-infected cells.

, 2014
ST cells were seeded into 6-cm culture plates, infected with TGEV, and the cytopathic effects (CPEs) were imaged at 24 (A), 40 (B), 48 (C), and 64 (D) hours following infection.
Ruili Ma (647617), Yanming Zhang (432346), Haiquan Liu (366589), Pengbo Ning (432342)   +3 more
core   +1 more source

Understanding TGEV-ETEC Coinfection through the Lens of Proteomics: A Tale of Porcine Diarrhea

, 2017
Porcine diarrhea and gastroenteritis are major causes of piglet mortality that result in devastating economic losses to the industry. A plethora of pathogens can cause these diseases, with TGEV and ETEC being two of the most salient.
Hamlet Adolfo Acevedo Ospina, Acevedo Ospina, Hamlet Adolfo, Guillermo Arango Duque, Arango Duque, Guillermo   +3 more
core   +1 more source

Myricetin inhibits transmissible gastroenteritis virus replication by targeting papain-like protease deubiquitinating enzyme activity

Frontiers in Microbiology
Myricetin, a natural flavonoid found in various foods, was investigated for its antiviral effect against transmissible gastroenteritis virus (TGEV). This α-coronavirus causes significant economic losses in the global swine industry.
Jiahao Fan, Pengyuan Xi, Huimao Liu, Xu Song, Xinghong Zhao, Xun Zhou, Yuanfeng Zou, Yuping Fu, Lixia Li, Renyong Jia, Zhongqiong Yin   +10 more
doaj   +1 more source