Results 101 to 110 of about 13,537 (210)

Structure and Encapsidation of Transmissible Gastroenteritis Coronavirus (TGEV) Defective Interfering Genomes [PDF]

open access: yes, 1995
Serial undiluted passages were performed with the PUR46 strain of TGEV in swine testis (ST) cells. Total cellular RNA was analyzed at different passages after orthophosphate metabolic labeling. Three new defective RNA species of 24, 10.5, and 9.5 kb (DI-A, DI-B, and DI-C respectively) were detected at passage 30, which were highly stable and ...
A, Méndez   +4 more
openaire   +2 more sources

Cellular RNA Helicase DDX1 Is Involved in Transmissible Gastroenteritis Virus nsp14-Induced Interferon-Beta Production

open access: yesFrontiers in Immunology, 2017
Transmissible gastroenteritis virus (TGEV), an enteropathogenic coronavirus (CoV) of porcine, causes lethal watery diarrhea and severe dehydration in piglets and leads to severe economic losses in the swine industry. Unlike most CoVs that antagonize type
Yanrong Zhou   +19 more
doaj   +1 more source

A Self‐Amplifying RNA Lipid Nanoparticle (saRNA‐LNP) Vaccine Provides Effective Protection Against Porcine Epidemic Diarrhea

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The development of vaccine platforms capable of inducing sustained, potent, and cost‐effective immunity remains a major challenge in veterinary vaccinology, particularly for coronaviruses, which are often associated with short‐lived vaccine‐induced protection.
Jinqi Shu   +12 more
wiley   +1 more source

Antiviral effects of Bovine antimicrobial peptide against TGEV in vivo and in vitro

open access: yesJournal of Veterinary Science, 2020
In suckling piglets, transmissible gastroenteritis virus (TGEV) causes lethal diarrhea accompanied by high infection and mortality rates, leading to considerable economic losses. This study explored methods of preventing or inhibiting their production.
Xiuli Liang   +11 more
openaire   +2 more sources

Determinants of TGEV S antigenic site A.

open access: yes, 2012
A. Binding of TGEV-neutralizing, site A-specific mAbs to RBD mutants. Relative binding (%) of mutants to wild type SA protein is shown for TGEV S-specific mAbs (top; described in Figure 1C) and a control anti-HA antibody (see Materials and Methods).
César Santiago (146919)   +5 more
core   +1 more source

Glucose promotes TGEV replication.

open access: yes, 2016
(A) IPEC-J2 cells were cultured in medium containing 0.1, 1, 10, or 25 mM glucose. Culture medium was then assayed. (B) Whole-cell extracts were prepared after TGEV infection for 48 h, and samples were analyzed for TGEV N and β-tubulin protein expression
Mi Xia (3350528)   +4 more
core   +1 more source

An Oral Vaccine for TGEV Immunization of Pigs

open access: yes, 2014
Transmissible gastroenteritis virus (TGEV) is a commercially important pathogen of hog farms and causes contagious, lethal diarrhea in piglets. While orally and parenterally administered vaccines made from inactivated or attenuated TGEV are commercially available, they require individual administration to piglets, which is time and labor intensive, and
openaire   +1 more source

UBXN1 interacts with the S1 protein of transmissible gastroenteritis coronavirus and plays a role in viral replication

open access: yesVeterinary Research, 2019
Transmissible gastroenteritis coronavirus (TGEV) is an enteropathogenic coronavirus that causes diarrhea in pigs and is associated with high morbidity and mortality in sucking piglets. S1 is one of two protein domains in the spike (S) glycoprotein and is
Peng Yuan   +8 more
doaj   +1 more source

Protein-protein interaction (PPI) network of the selected DEGs visualized with Cytoscape (TMEM41B-KO-MOCK vs. TMEM41B-KO-TGEV).

open access: yes, 2021
Differentially expressed genes in the "interferon signaling" pathway were marked with yellow. KO, knockout; TGEV, Transmissible gastroenteritis virus infected cells; Mock, uninfected cells. (TIF)
Limeng Sun (9321756)   +15 more
core   +1 more source

Levels of neutralizing antibodies in mice treated with pIRES-(TGEV-S1-PEDV-S1) and pIRES-(TGEV-S1-PEDV-S).

open access: yes, 2013
Anti-PEDV and anti-TGEV neutralizing antibodies in immunized mice were detected by plaque reduction assay with different serum dilutions from blood samples taken at 28 days after the injection of the plasmid DNAs.
Georg Herrler (199104)   +11 more
core   +1 more source

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