Results 81 to 90 of about 13,537 (210)
This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding +11 more
wiley +1 more source
Passive protection experiments were conducted to determine the frequency and amounts of hyperimmune antiserum needed to block a transmissible gastroenteritis virus (TGEV) challenge infection and to identify monoclonal antibodies that are partially ...
Ronald D. Wesley, Roger D. Woods
core +1 more source
A competitive inhibition ELISA was developed to detect non-neutralizing antibodies to the peplomer protein of transmissible gastroenteritis virus (TGEV) in porcine sera using a monoclonal antibody as an indicator. It was demonstrated that field strains of the TGEV-related porcine respiratory coronavirus (PRCV) did not induce this antibody, whereas the ...
Callebaut, P. +2 more
openaire +2 more sources
Interactions of Porcine Enteric Coronavirus TGEV with Macrophages and Lymphocytes [PDF]
Enterocytes covering the microvilli of small intestine are the only target cell of transmissible gastroenteritis (TGEV) that have been characterized until now. Such a tropism has been shown to explain the severe intestinal disorders affecting infected animals.
H. Laude, B. Charley, C. La Bonnardiere
openaire +1 more source
Immunotherapeutic Applications of Probiotics in Infectious Diseases Management: A Scoping Review
Probiotics are emerging as promising alternative therapies with diverse health applications, particularly in enhancing immunity and combating infectious diseases. This scoping review synthesizes evidence on the immunomodulatory and antimicrobial effects of well‐characterized strains, particularly species of Bifidobacterium and Lactobacillus. Probiotics
Samson Adedeji Adejumo +8 more
wiley +1 more source
Quantitative measurement of TGEV 3CLpro and S-X gene.
Viral RNA was extracted from cell lysates with or without LiCl treatment processed as described in M&M for real-time PCR. Reverse transcription was performed and the delta Ct value was measured at least in triplicate. The relative amplification of 3CLpro
Georg Herrler (199104) +6 more
core +1 more source
Background Transmissible gastroenteritis virus (TGEV) is one of the main pathogens causing severe diarrhea of piglets. The pathogenesis of TGEV is closely related to intestinal inflammation. All-trans retinoic acid (ATRA) is the main active metabolite of
Junning Pu +12 more
doaj +1 more source
Porcine epidemic diarrhea virus (PEDV) is an enteric alphacoronavirus that causes severe diarrhea and high mortality in neonatal piglets, posing a persistent threat to the global swine industry. Despite extensive vaccination, PEDV continues to circulate in China, underscoring the need for updated molecular epidemiological surveillance.
Yunlei Cao +8 more
wiley +1 more source
Downstream Ribosomal Entry for Translation of Coronavirus TGEV Gene 3b
Gene 3b (ORF 3b) in porcine transmissible gastroenteritis coronavirus (TGEV) encodes a putative nonstructural polypeptide of 27.7 kDa with unknown function that during translation in vitro is capable of becoming a glycosylated integral membrane protein of 31 kDa. In the virulent Miller strain of TGEV, ORF 3b is 5'-terminal on mRNA 3-1 and is presumably
O'Connor, Jennifer Black +1 more
openaire +2 more sources
Background Transmissible gastroenteritis virus (TGEV) is a devastating coronavirus that causes severe gastrointestinal symptoms and high mortality in piglets, resulting in substantial economic losses in the swine industry.
Jinhui Hou +11 more
doaj +1 more source

