Results 71 to 80 of about 13,537 (210)

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

open access: yesAdvanced Science, Volume 13, Issue 24, 27 April 2026.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu   +9 more
wiley   +1 more source

Prevalence of antibodies against transmissible gastroenteritis virus (TGEV) in Hungary

open access: yesVeterinary and Animal Science, 2019
Transmissible gastroenteritis (TGE) is a highly contagious enteric disease of swine, which became infrequent with the appearance of porcine respiratory coronavirus (PRCV). TGE was last reported in Hungary in 2013 and the virus has not been found since, therefore a serological survey was planned to estimate the level of protection against it.
Anna Valkó   +3 more
openaire   +3 more sources

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

open access: yesAdvanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras   +6 more
wiley   +1 more source

miR-27b attenuates apoptosis induced by transmissible gastroenteritis virus (TGEV) infection via targeting runt-related transcription factor 1 (RUNX1) [PDF]

open access: yes, 2016
Transmissible gastroenteritis virus (TGEV), belonging to the coronaviridae family, is the key cause of the fatal diarrhea of piglets and results in many pathological processes.
Xiangjun Song   +9 more
core   +1 more source

Sequence Analysis of CCV and its Relationship to FIPV, TGEV and PRCV [PDF]

open access: yes, 1994
Canine coronavirus (CCV), a causative agent of enteritis in newborn dogs, was first identified in 19711. The disease is characterized by infection of the absorptive epithelium of the villi and the onset of diarrhoea followed by villus atrophy2. The CCV virion is known to contain at least three protein species viz. the 204 kDa spike glycoprotein, S, the
B C, Horsburgh, T D, Brown
openaire   +2 more sources

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

open access: yesAdvanced Science, Volume 13, Issue 11, 23 February 2026.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su   +15 more
wiley   +1 more source

Identification of a natural recombinant transmissible gastroenteritis virus between Purdue and Miller clusters in ChinaEmerging of a natural recombinant TGEV in China

open access: yesEmerging Microbes and Infections, 2017
Transmissible gastroenteritis virus (TGEV) is an infective coronavirus (CoV) that causes diarrhea-related morbidity and mortality in piglets. For the first time, a natural recombination strain of a TGEV Anhui Hefei (AHHF) virus between the Purdue and the
Xin Zhang   +13 more
doaj   +1 more source

Hypovirus‐Induced Phosphorylation of CpIre1 Modulates Unfolded Protein Response and Virulence in Cryphonectria parasitica

open access: yesMolecular Plant Pathology, Volume 27, Issue 2, February 2026.
Hypovirus‐induced phosphorylation of CpIre1 modulates the endoplasmic reticulum stress response in Cryphonectria parasitica. ABSTRACT The chestnut blight fungus Cryphonectria parasitica and its hypovirus constitute a valuable model for investigating fungal pathogenesis and cross‐kingdom virus–host interplay.
Lijiu Zhao   +6 more
wiley   +1 more source

Analysis of the reproducibility and specificity of UNDP-PCR for TGEV.

open access: yes, 2015
(A) Three different concentrations of TGEV serum samples were detected by UNDP-PCR for TGEV in triplicates and in three independent runs. Lane M: Trans 2K Plus DNA Marker; lane 1–3: 5×103; lane 4–6: 5×102; lane 7–9: 5×101; lane10: negative samples.
Xiujuan Zhang (174319)   +7 more
core   +1 more source

Antigenic structures stably expressed by recombinant TGEV-derived vectors

open access: yesVirology, 2014
Coronaviruses (CoVs) are positive-stranded RNA viruses with potential as immunization vectors, expressing high levels of heterologous genes and eliciting both secretory and systemic immune responses. Nevertheless, its high recombination rate may result in the loss of the full-length foreign gene, limiting their use as vectors.
Martina Becares   +4 more
openaire   +2 more sources

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