Results 91 to 100 of about 13,537 (210)
Background Transmissible gastroenteritis virus (TGEV) has a sialic acid binding activity that is believed to be important for enteropathogenicity, but that has so far appeared to be dispensable for infection of cultured cells. The aims of this study were
Enjuanes Luis +5 more
doaj +1 more source
Environmental persistence of porcine coronaviruses in feed and feed ingredients. [PDF]
Porcine Epidemic Diarrhea Virus (PEDV), Porcine Delta Corona Virus (PDCoV), and Transmissible Gastroenteritis Virus (TGEV) are major threats to swine health and contaminated feed plays a role in virus transmission.
Michaela P Trudeau +5 more
doaj +1 more source
The devastating impact of porcine epidemic diarrhea virus (PEDV) on the global swine industry underscores an urgent need for effective antiviral therapies. Drug repurposing presents a promising strategy to accelerate the development of such treatments.
Yaqin Li +12 more
wiley +1 more source
TGEV infection promotes glucose uptake via increased protein expression of SGLT1 and GLUT2.
(A) IPEC-J2 cells were incubated with TGEV (MOI = 2) at 4°C for 1 h and then at 37°C. The culture medium was then collected at the indicated time points, and the glucose concentration in the medium was assayed.
Mi Xia (3350528) +4 more
core +1 more source
TMEM41B is a host factor required for TGEV replication.
(A) Verification of candidate genes enriched in the genome-wide CRISPR screen using a second, focused-CRISPR library screen. Scatter plots compare sgRNA targeted sequence frequencies and the extent of enrichment in the transformed PK-15-Cas9 cells (mock ...
Limeng Sun (9321756) +15 more
core +1 more source
The African swine fever virus (ASFV), particularly the genotypes I and II strains that have spread beyond Africa, continues to threaten global swine production and food security. Currently, African swine fever (ASF) control strategies rely heavily on biosecurity measures underpinned with molecular diagnostics.
Leilei Ding +15 more
wiley +1 more source
The internalization and early-stage replication of TGEV were impaired on TMEM41B KO cells.
(A) Evaluation of the adsorption activity of TGEV on TMEM41B KO and WT cells by absolute quantitative real-time PCR assay. WT and TMEM41B KO cells were infected with TGEV (MOI = 5) at 4°C for 1 h and assessed for TGEV adsorption.
Limeng Sun (9321756) +15 more
core +1 more source
Background Transmissible gastroenteritis virus (TGEV) causes enteric infection in piglets, characterized by vomiting, severe diarrhea and dehydration, and the mortality in suckling piglets is often high up to 100%.
Fujie Zhao +5 more
doaj +1 more source
Getah virus (GETV) is a mosquito‐borne alphavirus with an expanding host range and an increasing impact on swine production, particularly in neonatal piglets. In this study, a severe disease outbreak characterized by acute diarrhea and high mortality occurred among suckling piglets on a commercial pig farm in central China.
Zhengxin Yang +15 more
wiley +1 more source
TGEV corona virus ORF4 encodes a membrane protein that is incorporated into virions
The coding potential of the open reading frame ORF4 (82 amino acids) of transmissible gastroenteritis virus (TGEV) has been confirmed by expression using a baculovirus vector. Five monoclonal antibodies (MAbs) raised against the 10K recombinant product immunoprecipitated a polypeptide of a similar size in TGEV-infected cells.
Godet, Murielle +3 more
openaire +3 more sources

