Results 61 to 70 of about 13,537 (210)
Virulence, 2018 Transmissible gastroenteritis virus (TGEV) infection causes acute enteritis in swine of all ages, and especially in suckling piglets. Small intestinal inflammation is considered a central event in the pathogenesis of TGEV infections, and nuclear factor ...
Li Wang +12 more
doaj +1 more source
Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response
Advanced Science, Volume 13, Issue 59, 23 October 2026.This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du +10 more
wiley +1 more source
Advanced Science, Volume 13, Issue 54, 28 September 2026.Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou +11 more
wiley +1 more source
Genome-wide CRISPR screening to identify genes associated with alpha-CoVs TGEV-induced cell death.
, 2021 (A) Identification of TGEV host factors using the porcine genome-scale CRISPR/Cas9 knockout (PigGeCKO) library. Transformed PK-15-Cas9 cells were either mock-treated or challenged with TGEV (MOI = 0.001).
Limeng Sun (9321756) +15 more
core +1 more source
Frontiers in Veterinary Science, 2023 Currently, porcine coronaviruses are prevalent in pigs, and due to the outbreak of COVID-19, porcine coronaviruses have become a research hotspot.
Yan Li +11 more
doaj +1 more source
Advanced Healthcare Materials, Volume 15, Issue 26, 10 July 2026.A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao +9 more
wiley +1 more source
Sensitivity of bat cells to infection by TGEV.
, 2013 Bat cells (RoNi/7, HypNi/1.1, EpoNi/22.1, RhiLu/1.1, CpLu, Tb 1 Lu) were tranfected either with control plasmid (−pAPN) or with an expression plasmid for the porcine APN, the cellular receptor of TGEV (+pAPN).
Karl-Heinz Esser (417123) +12 more
core +1 more source
Health Science Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background and Aim Janus kinases/signal transducers and activators of transcription (JAK/STAT) pathway is crucial for various stages of immunity, from innate to adaptive responses. Type 1 IFNs activate JAK/STAT pathway by binding to receptors on JAK, phosphorylating STAT and upregulating interferon‐stimulated genes (ISGs) leading to cytokines ...
Esimebia Adjovi Amegashie +7 more
wiley +1 more source
Replication of Transmissible Gastroenteritis Coronavirus (TGEV) in Swine Alveolar Macrophages
Journal of General Virology, 1984 Several strains of the enteropathogenic coronavirus transmissible gastroenteritis virus (TGEV) have been shown to replicate in alveolar macrophages maintained in vitro. A distinct cytopathic effect was observed at a multiplicity of infection greater than or equal to 0.1. Infected cells released infectious virus.
H, Laude, B, Charley, J, Gelfi
openaire +2 more sources
Action mechanisms of lithium chloride on cell infection by transmissible gastroenteritis coronavirus. [PDF]
PLoS ONE, 2011 Transmissible gastroenteritis virus (TGEV) is a porcine coronavirus. Lithium chloride (LiCl) has been found to be effective against several DNA viruses, such as Herpes simplex virus and vaccinia virus. Recently, we and others have reported the inhibitory
Xiaofeng Ren +6 more
doaj +1 more source