Results 221 to 230 of about 138,672 (332)

Cutaneous Squamous Cell Carcinoma Amongst Solid Organ Transplant Recipients: A Systematic Review of Molecular Alterations

JEADV Clinical Practice, EarlyView.
ABSTRACT Background As solid organ transplantation becomes more prevalent, more patients are living on long‐term immunosuppression, greatly increasing the risk of cutaneous squamous cell carcinoma (cSCC). Although significant improvements have been achieved in the treatment of cSCC, further studies are needed to identify the specific protein expression
William Murray, Robin Caird, Michael O'Connor, Ciara Drumm, Emma O'Hora, Franklin Crossen, Aoife Lally, Aurelie Fabre, Roisin Dolan   +8 more
wiley   +1 more source

Additional file 13 of Fibroblast activation protein (FAP)-mediated promotion of metastasis via the FN1-TGFβ axis and immune suppression in aggressive thyroid cancer

Udinotti, Mario, Siebolts, Udo, Bauer, Marcus, Vaxevanis, Christoforos, Asiminas, Antonios, Lorenz, Kerstin, Dierks, Christine, Wickenhauser, Claudia, Seliger, Barbara   +8 more
openalex   +1 more source

Functional and histological evaluation of bone marrow stem cell-derived exosomes therapy on the submandibular salivary gland of diabetic Albino rats through TGFβ/ Smad3 signaling pathway [PDF]

, 2020
Nermeen AbuBakr, Tahany Haggag, Dina Sabry, Z. Salem   +3 more
openalex   +1 more source

Extracellular Vesicle‐Mediated Communication Between Anterior Cruciate Ligament and Bone Marrow Cells Modulates Hamstring Tenocyte Behavior and Apoptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Following anterior cruciate ligament (ACL) reconstruction, enhancing hamstring tenocyte activity and minimizing apoptosis are critical for preventing graft failure and promoting ligamentization. This study investigated the therapeutic potential of extracellular vesicles (EVs) derived from a coculture of ACL remnant cells and bone marrow ...
Hon‐Lok Lo, Shih‐Hao Huang, Ting‐Hsuan Dai, Shun‐Cheng Wu, Cheng‐Jung Ho, Cheng‐Chang Lu   +5 more
wiley   +1 more source

TGFβ signaling promotes cell cycle progression and resistance to the CDK4/6 inhibitor palbociclib through SOX4 transcriptional modulation in breast cancer cells. [PDF]

Cell Death Dis
Ali MM, Itoh Y, Badji AMP, Gallant S, Tsirigoti C, Bai Y, Filipek-Górniok B, Miyazawa K, Heldin CH, Moustakas A.   +9 more
europepmc   +1 more source

Differential effects of angiotensin II type I receptor blockers on reducing intraocular pressure and TGFβ signaling in the mouse retina

, 2018
Ralph J. Hazlewood, Qingxia Chen, Frances K. Clark, John Kuchtey, Rachel W. Kuchtey   +4 more
openalex   +2 more sources

TGFβ‐Mediated Overexpression of Podoplanin Serves as a Potential Diagnostic Biomarker in Acute Promyelocytic Leukemia

Molecular Carcinogenesis, EarlyView.
ABSTRACT Early diagnosis of acute promyelocytic leukemia (APL), driven by PML‐RARA oncoprotein, is vital for survival, as delays can cause fatal coagulopathy without prompt therapeutic intervention of all‐trans retinoic acid and arsenic trioxide. Although APL is diagnosed using microscopy, immunophenotyping, and FISH/PCR for PML‐RARA, morphological ...
Akash Maity, Rohit Kumar, Madhavi Dutta, Ansit Mishra, Jitendra Gawde, Jagruti Patil, Darshana Kadam, Sumeet Mirgh, Anant Gokarn, Hasmukh Jain, Lingaraj Nayak, Bhausaheb Bagal, Sachin Punatar, Manju Sengar, Navin Khattry, P. G. Subramanian, Prashant Tembhare, Syed K. Hasan   +17 more
wiley   +1 more source

HDL Regulates TGFβ-Receptor Lipid Raft Partitioning, Restoring Contractile Features of Cholesterol-Loaded Vascular Smooth Muscle Cells. [PDF]

JACC Basic Transl Sci
Nagesh PT, Rawal S, Nishi H, Zahr T, Miano JM, Sorci-Thomas M, Xu H, Akbar N, Choudhury RP, Feinberg MW, Misra A, Fisher EA.   +11 more
europepmc   +1 more source

Systematic Review of Percutaneous and Transcutaneous Posterior Tibial Neurostimulation for Lower Urinary Tract Symptoms & Lower Urinary Tract Dysfunction in Children

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective To systematically evaluate the efficacy of posterior tibial nerve stimulation (TNS) in children with lower urinary tract symptoms (LUTS) and/or lower urinary tract dysfunction (LUTD). Materials and Methods A systematic review was conducted following PRISMA guidelines.
Zoe S. Gan, Suhaib Abdulfattah, Jennifer Lege‐Matsuura, Katherine M. Fischer, Jason P. Van Batavia   +4 more
wiley   +1 more source

Enhanced antitumor efficacy of combined targeting of adenosine A_2B receptor and PD-1 is mediated via multiple effects on different cell populations within tumor microenvironment. [PDF]

Cancer Immunol Immunother
Guan S, Wang C, Amann JM, Cho JH, Ma Q, Carbone DP.   +5 more
europepmc   +1 more source