Histiocytes: Multifaceted Regulators of Health and Disease
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
TGFβ induces an atypical EMT to evade immune mechanosurveillance in lung adenocarcinoma dormant metastasis. [PDF]
Wang Z +9 more
europepmc +1 more source
Abstract Objective The purpose of this case series was to describe the effect of autologous PRF membrane for corneal reconstruction surgery in dogs. PRF membranes made from two healthy dogs unrelated to the current case series were used for PRF histologic analyses. Animals Seven dogs with complicated corneal ulcerations. Procedure A complete ophthalmic
Louise Baadsgaard Bruun +6 more
wiley +1 more source
The tumor microenvironment of cutaneous squamous cell carcinoma in high-risk patient groups: A scoping review. [PDF]
Wang W +5 more
europepmc +1 more source
ABSTRACT The Amazon and Atlantic forests harbour immense biodiversity shaped by complex evolutionary history with diverse processes leading to species build‐up. We investigated the Cinereous Antshrike species complex (Thamnomanes caesius and T. schistogynus) to disentangle the relative contributions of riverine barriers and historical climatic ...
Henrique Batalha‐Filho +6 more
wiley +1 more source
Versatile SMAD2 and SMAD3 epitope-tagged mouse models for genomic profiling of TGFβ signaling: Uncovering GDF9-SMAD2/3 targets. [PDF]
Liao Z +7 more
europepmc +1 more source
Senolytics and exercise: Dual modalities for rejuvenating muscle
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
Obesity- and tumor-derived signals drive cancer-associated state transitions in breast mesenchymal stromal/stem cells reprogrammed by IL1RA or JAK inhibition. [PDF]
Ritter A +10 more
europepmc +1 more source
Abstract figure legend Transforming growth factor (TGF)‐β2 and interleukin (IL)‐1β induced morphological and molecular changes consistent with endothelial‐to‐mesenchymal transition (EndMT) in HUVECs isolated from both pregnancies complicated by gestational diabetes (GDM) and non‐GDM pregnancies.
Abigail R. Byford +9 more
wiley +1 more source
Correction: LXRα limits TGFβ-dependent hepatocellular carcinoma associated fibroblast differentiation. [PDF]
Morén A +6 more
europepmc +1 more source

