Results 221 to 230 of about 132,620 (281)

Aging-Driven Immunosuppression: The Role of Tregs in the Ovarian Tumor Microenvironment. [PDF]

Aging Cell
Udumula MP, Km A, Rashid F, Nematullah M, Singh H, Bhardwaj T, Hijaz M, Giri S, Chini EN, Gibson HM, Rattan R.   +10 more
europepmc   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Administration of Topical NorLeu³Angiotensin(1-7) Minimizes Fibrotic Corneal Healing in Stellate Wound: A 28-Day Study. [PDF]

Int J Mol Sci
Chester C, Moreno-Diaz EA, Hu W, Chen B, Alshammari M, Humayun MS, Camarillo JCM, Louie SG.   +7 more
europepmc   +1 more source

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

Photochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio, Sanjay Anand, Jeffrey B. Travers, Edward V. Maytin, Craig A. Rohan   +4 more
wiley   +1 more source

WWP1 gain-of-function drives developmental anoikis through TGFβ pathway during neurodevelopment. [PDF]

Cell Death Discov
So KH, Lee S, Wong J, Lee H, Yun EJ, Jang SS, Choi HJ, Chae JH, Baek ST.   +8 more
europepmc   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Correction to: Endothelial-to-Osteoblast Conversion maintains bone homeostasis through Kindlin-2/Piezo1/TGFβ/Runx2 axis. [PDF]

Protein Cell
europepmc   +1 more source

Calibrating tissue level PDE models of ligand dynamics using single cell and spatial transcriptomics data. [PDF]

NPJ Syst Biol Appl
Daher A, Trucu D, Eftimie R.
europepmc   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source

TGFβ pathway represses hepatic ribosome biogenesis and protein synthesis by regulating p70S6K-S6RP proteins. [PDF]

Cell Mol Biol Lett
Stavropoulos A, Stamatopoulou V, Pavlos E, Manioudaki M, Sakellariou S, Stathopoulos C, Xilouri M.   +6 more
europepmc   +1 more source