Results 261 to 270 of about 132,620 (281)

GTX-11 attenuates lung fibrosis, inflammation and vascular remodeling in preclinical models of lung fibrotic disease. [PDF]

Front Pharmacol
Montes-Worboys A, Milara J, Farrera C, Fernández-Asensio C, Sánchez-Díez S, Mercadé J, Montero P, Roger I, Molina-Molina M, Ruiz-Cánovas E, Cortijo J.   +10 more
europepmc   +1 more source

Deletion of a Pax1 Sex‐Associated Genomic Region Associated With Adolescent Idiopathic Scoliosis Leads to Disc Degeneration, Instability, and Vertebral Rotation in Mice

JOR SPINE, Volume 9, Issue 2, June 2026.
Overview of the effects of Pax1‐SAR deletion on gene expression, IVD degeneration, and resultant scoliotic‐like curvature between sexes. Proposed mechanism of sex‐dependent changes in gene expression in females (right) and males (left), resulting in sex‐dependent disc degeneration and scoliotic phenotypes.
Edward C. Moody, Emma M. Wade, Shuji Mizumoto, Jeremy McCallum‐Loudeac, Megan J. Wilson   +4 more
wiley   +1 more source

Attenuation of epicardial activation and myofibroblast abundance via the Fbln2-Nupr1b axis stimulates cardiac regeneration in zebrafish. [PDF]

Nat Cardiovasc Res
Kayman Kürekçi G, Kaur Bajwa G, Zhang S, Leclerc S, de Chantal E, Belke D, Andelfinger G, Deniset JF, Marín-Juez R.   +8 more
europepmc   +1 more source

Platelet‐Rich Fibrin Induces New Bone Formation to Promote Extreme Lateral Interbody Fusion of Spine in Rabbits

JOR SPINE, Volume 9, Issue 2, June 2026.
Preparation process of PRF and its promotion of intervertebral fusion. The rabbit lateral fusion model proves that PRF can promote the intervertebral fusion rate of allograft bone. In vitro experiments can be observed that PRF promotes the osteogenic expression of BMSCS.
Weijian Wang, Jiaqi Li, Han Wu, Sidong Yang, Shaorong Li, Wei Zhang   +5 more
wiley   +1 more source

Translating Fibrosis to Malignancy: Biomarkers and Therapeutic Opportunities in Liver Fibrosis and Hepatocellular Carcinoma. [PDF]

Med Sci (Basel)
Neureiter D, Kiesslich T, Ocker M.
europepmc   +1 more source

The Role of N6‐Methyladenosine Modification in Health and Disease

MedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li   +6 more
wiley   +1 more source

Mechanisms of mitral valve development and disease. [PDF]

Front Cardiovasc Med
Wang E, Zhou B.
europepmc   +1 more source

Organoids: From Bench to Bedside Applications

MedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li, Rui Cao, Maochen Li, Zichao Tian, Huahao Fan, Bixia Hong, Xiaojuan Liu   +6 more
wiley   +1 more source

Non-Canonical Wnt11 Signaling Regulates Pulmonary Fibrosis via Fibroblast and Alveolar Epithelial Type II Cell Crosstalk. [PDF]

Int J Mol Sci
Gonzalez De Los Santos F, Ando A, Hu B, Rosek A, Phan SH, Liu T.   +5 more
europepmc   +1 more source

Electro-acupuncture attenuates cyclophosphamide-induced premature ovarian insufficiency in rats through miRNA regulation and TGFβ/Smad pathway modulation. [PDF]

Am J Transl Res
Xian J, Zhao R, Chen Y, Khan MJ, Jamil M, Alfuraydi AA, Alsabih AO, Almutairi S, Umair M, Hameed Y.   +9 more
europepmc   +1 more source