Results 61 to 70 of about 169,083 (155)

The regulation of NOX4 expression by insulin and its role in the modulation of TGF-ß-induced apoptosis in murine hepatocytes

, 2011
Nous avons analysé le rôle joué par insulin, IGF-1 et IGF-2 sur le expression de la NADPH oxidase NOX4 dans une model hépatocellulaire et exploré son implication à l'interface des signalisations de IGF-1/2 et TGF-ß.
Wang, Wei
core   +1 more source

Tempol, a Superoxide Dismutase-Mimetic Drug, Ameliorates Progression of Renal Disease in CKD Mice

Cellular Physiology and Biochemistry, 2015
Background: Oxidative stress has been implicated in the pathogenesis of chronic kidney disease (CKD) and antioxidants may ameliorate disease progression.
Wei Ding, Bin Wang, Minmin Zhang, Yong Gu   +3 more
doaj   +1 more source

TGF-ß mediates the response of MDA-MB-231 cells to substrate rigidity.

, 2013
(A) PTHrP gene expression increases significantly for MDA-MB-231 cells transfected with the plasmid control (MDA-pc), while MDA-MB-231 cells transfected to express a dominant negative form of the TGF-ß Type II receptor (MDA-TβRIIcyt ) and MCF-7 cells ...
Alyssa R. Merkel (359829), Nazanin S. Ruppender (359828), Scott A. Guelcher (359831), Julie A. Sterling (150787), Gregory R. Mundy (298332), T. John Martin (359830)   +5 more
core   +1 more source

Combined targeting of soluble latent TGF-ß and a solid tumor-associated antigen with adapter CAR T cells. [PDF]

Oncoimmunology, 2022
Werchau N, Kotter B, Criado-Moronati E, Gosselink A, Cordes N, Lock D, Lennartz S, Kolbe C, Winter N, Teppert K, Engert F, Webster B, Mittelstaet J, Schaefer D, Mallmann P, Mallmann MR, Ratiu D, Assenmacher M, Schaser T, von Bergwelt-Baildon M, Abramowski P, Kaiser AD.   +21 more
europepmc   +1 more source

Endothelial cells were incubated overnight in medium that contained [KCl], 0 and 5 mM, and a neutralizing anti-TGF-ß antibody or nonspecific IgG.

, 2013
The observed increase in PIP3 content in cells in the low-potassium medium was inhibited by the addition of the anti-TGF-ß antibody, which did not affect PIP3 levels in cells incubated in medium containing 5 mM [KCl].
Kristal J. Aaron (300051), Wei-Zhong Ying (300050), Paul W. Sanders (221228)   +2 more
core   +1 more source

Radiosensitizing effect of galunisertib, a TGF-ß receptor I inhibitor, on head and neck squamous cell carcinoma in vitro. [PDF]

Invest New Drugs, 2022
Jank BJ, Lenz T, Haas M, Kadletz-Wanke L, Campion NJ, Schnoell J, Heiduschka G, Macfelda K.   +7 more
europepmc   +1 more source

Correlation of changes in morphology and TGF-ß expression during human umbilical cord development [PDF]

, 2000
grantor: University of TorontoThe umbilical cord is a unique structure that acts as a vascular link between the mother and fetus. The factors regulating its development are poorly understood.
Copland, Ian
core   +1 more source

Einfluß von NGF auf die TGF-ß/Smad Signaltransduktion in PC12 Zellen

, 2002
Transforming growth factor-ß (TGF-ß) is a multifunctional cytokine that is engaged in regulating versatile cellular processes that are pivotal for development and homeostasis of most tissues in multicellular organisms.
Lutz, Marion
core   +1 more source

Expresión del factor ? transformador del crecimiento (TGF-?) y del factor de crecimiento derivado de las plaquetas (PDFG) en la esclerodermia lineal

Biomédica: revista del Instituto Nacional de Salud, 2003
La esclerodermia lineal (EL) es una forma localizada de la enfermedad, caracterizada por la proliferación fibroblástica y los infiltrados linfocitarios perivasculares en la dermis.
José Félix Restrepo, Renato Guzmán, Gerzaín Rodríguez, Antonio Iglesias   +3 more
doaj   +1 more source

Administration of TGF-ß Inhibitor Mitigates Radiation-induced Fibrosis in a Mouse Model. [PDF]

Clin Orthop Relat Res, 2021
Gans I, El Abiad JM, James AW, Levin AS, Morris CD.   +4 more
europepmc   +1 more source