Results 41 to 50 of about 169,083 (155)

Participation of the SMAD2/3 signalling pathway in the down regulation of megalin/LRP2 by transforming growth factor beta (TGF-ß1).

open access: yesPLoS ONE, 2019
Megalin/LRP2 is a receptor that plays important roles in the physiology of several organs, such as kidney, lung, intestine, and gallbladder and also in the physiology of the nervous system.
Felipe Cabezas   +2 more
doaj   +1 more source

TGF-ß alterations in oral squamous cell carcinoma. Narrative review.

open access: yes, 2016
The transforming growth factor beta (TGF-ß) is a cytokine that plays crucial roles in the regulation of angiogenesis, immune response, proliferation, migration and apoptosis of cells.
Alejandra Fernández   +11 more
core   +1 more source

The efficacy of platelet-derived wound healing formula (PDWHF) in diabetic foot ulcers: Revisited [PDF]

open access: yesAin-Shams Journal of Surgery, 2010
Background: Diabetic ulcer of the foot is a major health problem with a high socioeconomic impact and may finally progress to amputation. Methods: Forty patients suffering diabetic foot ulcers with history of non-healing for 8 weeks at least were ...
Nahed S Boughdadi   +5 more
doaj   +1 more source

Pathogenic role of TGF-ß in the progression of podocyte diseases [PDF]

open access: yes, 2011
In patients with progressive podocyte diseases, such as focal segmental glomerulosclerosis and membranous nephropathy, there is enhanced expression of transforming growth factor (TGF-ß) in podocytes.
Lee, Hyun Soon
core  

Transforming growth factor beta (TGF-ß), mesenchymal-epithelial transition (MET) and breast cancer metastasis

open access: yes, 2014
© 2014 Optimal Clinical (Doctors. MD).Genetic and microenviromental factors model the tissue architecture. The advance of gene expression profiling and individual tumor characterizing analysis have enabled to identify the clinical significance of ...
Demirkan, Binnaz Hatice Mirac   +1 more
core   +1 more source

Immunoregulatory Cytokine (TGF-ß And IL-10) Responses in Mice Inoculated With Protoscoleces and Major Hydatid Fluid Antigens of Cystic Echinococcosis [PDF]

open access: yesIranian Journal of Parasitology, 2008
"nBackground: Our objectives were to investigate whether immunomodulatory cytokines, TGF-β and IL-10, are stimulated in response to cystic echinococcosis (CE) components in mice model, and whether major hydatid fluid antigens or live protoscoleces could ...
MB Ghavami   +3 more
doaj   +2 more sources

Differential role of mesangial cells and podocytes in TGF-ß-induced mesangial matrix synthesis in chronic glomerular disease [PDF]

open access: yes, 2009
Glomerulosclerosis is characterized by mesangial matrix accumulation that is mediated primarily by activation of transforming growth factor-ß (TGF-ß). Unlike podocytes, mesangial cells secrete TGF-ß in response to common in vitro fibrogenic stimuli.
Lee, Hyun Soon, Song, Chi Young
core  

Transforming growth factor β1 inhibition protects from noise-induced hearing loss

open access: yesFrontiers in Aging Neuroscience, 2015
Excessive exposure to noise damages the principal cochlear structures leading to hearing impairment. Inflammatory and immune responses are central mechanisms in cochlear defensive response to noise but, if unregulated, they contribute to inner ear damage
Silvia eMurillo-Cuesta   +19 more
doaj   +1 more source

Canagliflozin and irbesartan ameliorate renal fibrosis via the TGF-β1/Smad signaling pathway in Dahl salt-sensitive rats

open access: yesJournal of International Medical Research, 2023
Objectives This study assessed the antifibrotic effects of canagliflozin, with or without irbesartan, on renal injury in Dahl salt-sensitive (SS) rats fed a high-salt (HS) diet.
Jianlong Zhai   +8 more
doaj   +1 more source

Effects of cold atmospheric plasma (CAP) on ß-defensins, inflammatory cytokines, and apoptosis-related molecules in keratinocytes in vitro and in vivo. [PDF]

open access: yesPLoS ONE, 2015
Cold atmospheric plasma (CAP) has been gaining increasing interest as a new approach for the treatment of skin diseases or wounds. Although this approach has demonstrated promising antibacterial activity, its exact mechanism of action remains unclear ...
Stephanie Arndt   +9 more
doaj   +1 more source

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