Results 51 to 60 of about 169,083 (155)

Paracrine role for TGF-ß-induced CTGF and VEGF in mesangial matrix expansion in progressive glomerular disease [PDF]

open access: yes, 2012
Transforming growth factor-ß (TGF-ß) is a key regulator of extracellular matrix (ECM), and may mediate the development of glomerulosclerosis with accumulation of mesangial matrix.
Soon Lee, Hyun
core  

Transforming growth factor beta activity in urine of patients with type 2 diabetes and diabetic nephropathy

open access: yesBrazilian Journal of Medical and Biological Research, 1999
Diabetic nephropathy (DN) is characterized structurally by progressive mesangial deposition of extracellular matrix (ECM). Transforming growth factor-ß (TGF-ß) is considered to be one of the major cytokines involved in the regulation of ECM synthesis and
Rivarola E.W.R.   +5 more
doaj  

Effect of TGF-ß RII mutation on TGF-ß signaling [PDF]

open access: yes, 2013
We have previously reported I170T mutation of transforming growth factor- ß receptor II (TßR-II) in human oral squamous cell carcinoma samples. To analyze the functional consequences of I170T TßR-II mutation, we performed co-immunoprecipitation of TßR-II
김진, 손화경
core  

IL-10 Inhibits Transforming Growth Factor-ß-Induction of Type I Collagen mRNA Expression via Both JNK and p38 Pathways in Human Lung Fibroblasts [PDF]

open access: yes, 2005
Transforming growth factor-ß (TGF-ß) is a key factor for understanding the pathogenesis of fibrotic disorders such as idiopathic pulmonary fibrosis (IPF).
Tachibana, Isao   +13 more
core   +1 more source

Development of a Human IFN-ß Expression System using Chinese Hamster Ovarian Cells

open access: yes, 2023
Two human IFN-ß expression systems were derived based on the pIRES2-AcGFP1 plasmid backbone. One expression plasmid encoded human IFN-ß fused to a C-terminal linker and an 8-histidine affinity chromatography tag. A second expression plasmid encoded human
Hylton, Todd Cameron   +1 more
core  

Expression of TGF-ß signaling proteins in normal placenta and gestational trophoblastic disease [PDF]

open access: yes, 2007
The transforming growth factor ß (TGF-ß) is a vital regulator of placental development and functions. TGF-ß exerts several modulatory effects on trophoblast cells, such as inhibition of proliferation and invasiveness, and stimulation of ...
Shin, Y.K.   +7 more
core  

Andstæð hlutverk TGF-ß fjölskyldunnar í bandvefsumbreytingu í fylgjumyndun og meðgöngueitrun

open access: yes, 2022
The pregnancy disease preeclampsia (PE) affects around 2-8% of pregnancies worldwide and is one of the leading causes for maternal, fetal and neonatal morbidity and mortality.
Hallfríður Ingólfsdóttir 1996-
core   +1 more source

Molecular Pathogenesis of Desmoid Tumors

open access: yesIranian Journal of Public Health, 2005
Desmoid tumors (aggressive fibromatosis) are locally invasive soft tissue tumors in which beta-catenin/TCF3 mediated Wnt signaling is activated. More than 80% of desmoid tumors contain activating mutations in ß-Catenin which leads to up-regulation of ß ...
S Amini Nik   +4 more
doaj  

Medium [KCl] affects endothelial cell production of total and active TGF-ß.

open access: yes, 2013
Medium concentrations of total and active TGF-ß were determined following overnight incubation in medium that contained [KCl], 0 mM, (termed Baseline), and in medium supplemented with 5 mM of either KCl or NaCl.
Kristal J. Aaron (300051)   +2 more
core   +1 more source

Abstract 3185: Expression of DNA methyltransferase (DNMT) induced by transforming growth factor-ß (TGF-ß) promotes progress of prostate cancer

open access: yes, 2010
Purpose: Loss of sensitivity to TGF-ß are features associated with advanced prostate cancer. Previously, we reported that TGF-ß induced DNMT are associated with aggressive prostate cancer (CaP) cell lines.
Thomas Jang   +5 more
core   +1 more source

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