Results 51 to 60 of about 169,083 (155)
Paracrine role for TGF-ß-induced CTGF and VEGF in mesangial matrix expansion in progressive glomerular disease [PDF]
Transforming growth factor-ß (TGF-ß) is a key regulator of extracellular matrix (ECM), and may mediate the development of glomerulosclerosis with accumulation of mesangial matrix.
Soon Lee, Hyun
core
Diabetic nephropathy (DN) is characterized structurally by progressive mesangial deposition of extracellular matrix (ECM). Transforming growth factor-ß (TGF-ß) is considered to be one of the major cytokines involved in the regulation of ECM synthesis and
Rivarola E.W.R. +5 more
doaj
Effect of TGF-ß RII mutation on TGF-ß signaling [PDF]
We have previously reported I170T mutation of transforming growth factor- ß receptor II (TßR-II) in human oral squamous cell carcinoma samples. To analyze the functional consequences of I170T TßR-II mutation, we performed co-immunoprecipitation of TßR-II
김진, 손화경
core
IL-10 Inhibits Transforming Growth Factor-ß-Induction of Type I Collagen mRNA Expression via Both JNK and p38 Pathways in Human Lung Fibroblasts [PDF]
Transforming growth factor-ß (TGF-ß) is a key factor for understanding the pathogenesis of fibrotic disorders such as idiopathic pulmonary fibrosis (IPF).
Tachibana, Isao +13 more
core +1 more source
Development of a Human IFN-ß Expression System using Chinese Hamster Ovarian Cells
Two human IFN-ß expression systems were derived based on the pIRES2-AcGFP1 plasmid backbone. One expression plasmid encoded human IFN-ß fused to a C-terminal linker and an 8-histidine affinity chromatography tag. A second expression plasmid encoded human
Hylton, Todd Cameron +1 more
core
Expression of TGF-ß signaling proteins in normal placenta and gestational trophoblastic disease [PDF]
The transforming growth factor ß (TGF-ß) is a vital regulator of placental development and functions. TGF-ß exerts several modulatory effects on trophoblast cells, such as inhibition of proliferation and invasiveness, and stimulation of ...
Shin, Y.K. +7 more
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Andstæð hlutverk TGF-ß fjölskyldunnar í bandvefsumbreytingu í fylgjumyndun og meðgöngueitrun
The pregnancy disease preeclampsia (PE) affects around 2-8% of pregnancies worldwide and is one of the leading causes for maternal, fetal and neonatal morbidity and mortality.
Hallfríður Ingólfsdóttir 1996-
core +1 more source
Molecular Pathogenesis of Desmoid Tumors
Desmoid tumors (aggressive fibromatosis) are locally invasive soft tissue tumors in which beta-catenin/TCF3 mediated Wnt signaling is activated. More than 80% of desmoid tumors contain activating mutations in ß-Catenin which leads to up-regulation of ß ...
S Amini Nik +4 more
doaj
Medium [KCl] affects endothelial cell production of total and active TGF-ß.
Medium concentrations of total and active TGF-ß were determined following overnight incubation in medium that contained [KCl], 0 mM, (termed Baseline), and in medium supplemented with 5 mM of either KCl or NaCl.
Kristal J. Aaron (300051) +2 more
core +1 more source
Purpose: Loss of sensitivity to TGF-ß are features associated with advanced prostate cancer. Previously, we reported that TGF-ß induced DNMT are associated with aggressive prostate cancer (CaP) cell lines.
Thomas Jang +5 more
core +1 more source

