Results 91 to 100 of about 202,654 (267)
RAGE and TGF-β1 Cross-Talk Regulate Extracellular Matrix Turnover and Cytokine Synthesis in AGEs Exposed Fibroblast Cells. [PDF]
PLoS ONE, 2016 AGEs accumulation in the skin affects extracellular matrix (ECM) turnover and triggers diabetes associated skin conditions and accelerated skin aging.
Andreea Iren Serban +4 more
doaj +1 more source
Advanced Science, EarlyView.This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha +5 more
wiley +1 more source
ADP355 reduced TGF-β1 expression. [PDF]
, 2014 A) Representative of Western blot analysis for TGF-β1 (Top panel), densitometric analysis presented in bottom panel. B) mRNA expression of TGF-β1 total RNA obtained from whole liver tissue lysates, data are represented as the TGF-β1 expression relative ...
Tekla Smith (643654) +4 more
core +1 more source
Advanced Science, EarlyView.Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang +10 more
wiley +1 more source
Bone-Conditioned Medium Obtained From Calvaria, Mandible, and Tibia Cause an Equivalent TGF-β1 Response In Vitro. [PDF]
, 2018 Bones with different embryological origin and mode of ossification are supposed to vary in their capacity for supporting graft consolidation. The aim of the current pilot study was to assess the TGF-β1 activity of bone chips obtained from distinct ...
Gruber, Reinhard +9 more
core +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
, 2015 Effect of curcumin on mRNA expression of TGF-β1 (A) RT-PCR of TGF-β1 and β-actin (B) Densitometric scanning of TGF-β1 after normalization with β-actin.
Laxmidhar Das (578450) +1 more
core +1 more source
Zhongguo aizheng zazhi, 2018 Background and purpose: Abnormal expression and amplification of transforming growth factor beta 1 (TGF-β1) and Notch3 in ovarian carcinoma tissues are associated with metastasis and low survival rate, respectively.
周韵娇, 王婧姝, 梁 凡
doaj
Advanced Science, EarlyView.Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu +10 more
wiley +1 more source
Additional file 2: of LncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation [PDF]
, 2019 Figure S2. Effect of miR-128-3p mimic and Sp1 silencing on the PVT1 overexpression-induced secretion of TGF-β1. Levels of TGF-β1 were measured using ELISA. *P
Ling Yan (555222) +4 more
core +1 more source