Results 31 to 40 of about 104,379 (168)
Engineering Bisubstrates to Target m6Am RNA Methyltransferases: Synthesis and Computational Studies
Use of the convertible nucleoside approach to synthesize m6Am RNA methyltransferase bisubstrates. This methodology allows for the introduction of modifications on the SAM analog moiety and the RNA substrate part, including the introduction of a cap analog by click chemistry.
Yoann Colas +3 more
wiley +1 more source
RésuméDans le cadre de cet article, nous proposons d’analyser les mutations pénales à partir d’un aspect plus particulier qui est celui de la finalité thérapeutique attribuée à certaines pratiques pénales.
Bastien Quirion
doaj +1 more source
Cycloadditions have emerged as some of the most useful reactions for the formation of polycyclic compounds. The carbonylative cycloaddition of triynes can lead to carbonylative and non-carbonylative competitive pathways, each leading to the formation of ...
Laura Salacz +3 more
doaj +1 more source
Efficacy of DOTS strategy in treatment of respiratory tuberculosis in Gorgan, Islamic Republic of Iran [PDF]
We carried out a follow-up cohort study of 260 smear-positive patients (178 on directly observed treatment, short-course (DOTS); 82 on non-DOTS] over a 2-year period to evaluate the efficacy of the DOTS strategy in treatment of tuberculosis (TB). All the
Abassi, A., Mansourian, A.R.
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Abstract Background Unexplained exertional dyspnoea without significant elevation of natriuretic peptides is common. One of the causes might be early heart failure with preserved ejection fraction (HFpEF). Aims This study aimed to characterize patients with exertional dyspnoea and normal/near‐to‐normal N‐terminal pro‐brain natriuretic peptide (NT ...
Emmanuelle Berthelot +8 more
wiley +1 more source
The silent burden of anaemia in Tanzania children:a community-based study [PDF]
Objective was to document the prevalence, age-distribution, and risk factors for anaemia in Tanzanian children less than 5 years old,thereby assisting in the development of effective strategies for controlling anaemia.\ud \ud Cluster sampling was used to
Armstrong Schellenberg, J R M +6 more
core +1 more source
Divergent Synthesis of Polycyclic Derivatives via Gold Catalysis
Gold(I)‐catalyzed cycloisomerization enables the formation of complex 3D structures from simple enyne precursors. This study presents a divergent strategy to synthesize functionalized bicyclic and tricyclic scaffolds from a common alkynyl ketone.
Emilie Gentilini +4 more
wiley +1 more source
L’objectif de cette étude était d’identifier les facteurs qui influencent le choix de la dialyse péritonéale (DP) chez les patients insuffisants rénaux, dans un centre de dialyse en France offrant un dispositif d’éducation thérapeutique du patient (ETP ...
Abdou Simon Senghor
doaj +1 more source
Objective A systematic review of clinical trials on thermal ablation of T1b RCC was conducted to assess oncologic outcomes of those procedures. The primary endpoint was the rate of local recurrence.
Grégoire Cazalas +7 more
doaj +1 more source
Santiniketan: Exploration anthropologico-médicale de l'offre de soins dans un contexte de pluralisme thérapeutique. [PDF]
Contexte : Le processus de mondialisation en cours engendre une mise en contact de différentes cultures et, par extension de leurs systèmes médicaux, de leurs savoirs et de leurs pratiques.
SIMONIN, V.
core

