Results 21 to 30 of about 43,670 (169)

Saikosaponin A Inhibits Breast Cancer by Regulating Th1/Th2 Balance

Frontiers in Pharmacology, 2019
Saikosaponin A (SSa) is isolated from the dried root of Radix Bupleuri, an herb widely used in traditional Chinese medicine, exerting antitumor activities.
Xin Zhao, Jinyu Liu, Shasha Ge, Chen Chen, Shuang Li, Xiaoyu Wu, Xuanye Feng, Yueqi Wang, Da-yong Cai   +8 more
semanticscholar   +1 more source

A Review of Life Cycle Construction Process and Cutting-Edge Technology in Prefabricated MEP Installation Engineering

Buildings
Prefabricated installation, a pivotal study in the realm of contemporary construction practices, delves into the utilization of prefabrication within mechanical, electrical, and plumbing (MEP) systems.
Gangwen Yan, Yinghui Yang, Huizhong Zhang, Zhenwei Li, Song Chen, Xuefeng Zhao, Zhe Sun, Xiongtao Fan, Meng Zhang, Lingli Huang, Liang Liu   +10 more
doaj   +1 more source

Shear Behavior and Design of Innovative Stud-Reinforced Embedded Shear Connectors with Flanges

Buildings
The embedded shear connector with flanges (ESCF) exhibits excellent shear performance in the steel–concrete composite beam. The ESCF consists of embedded corrugated steel web as the shear connector and shape-matched flanges for construction convenience ...
Zhe Zhang, Wenhao Jin, Enfeng Deng, Chenyang Yu, Weidong Wan, Changzhi Duan, Lian Zhang, Shibo Wang   +7 more
doaj   +1 more source

TIGIT signaling restores suppressor function of Th1 Tregs.

JCI Insight, 2019
Th1 Tregs are characterized by the acquisition of proinflammatory cytokine secretion and reduced suppressor activity. Th1 Tregs are found at increased frequency in autoimmune diseases, including type 1 diabetes and multiple sclerosis (MS).
Liliana E. Lucca, Pierre-Paul Axisa, Emily Singer, Neal M Nolan, M. Dominguez‐Villar, D. Hafler   +5 more
semanticscholar   +1 more source

Implementation of Building Information Modeling Technologies in Wood Construction: A Review of the State of the Art from a Multidisciplinary Approach

Buildings
This research raises questions about the possibilities and options of using the BIM methodology associated with software for the wood design and construction of structure modeling along an asset’s cycle life.
Danny Lobos Calquin, Ramón Mata, Claudio Correa, Eduardo Nuñez, Guillermo Bustamante, Natalia Caicedo, David Blanco Fernandez, Marcos Díaz, Pablo Pulgar-Rubilar, Leonardo Roa   +9 more
doaj   +1 more source

A Study of the Effects of Historical Block Context on Soundscape Perception

Buildings
This study aims to explore the influence of spatial functional differences on the overall relationship between soundscape and visual landscape in the context of historical blocks and then propose design guidelines for audiovisual elements.
Jing Ye, Shumin Li, Youcheng Chen, Yongqiang Ma, Lingyan Chen, Tianyou He, Yushan Zheng   +6 more
doaj   +1 more source

Parkinson’s disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patients

Journal of Neuroinflammation, 2018
Parkinson’s disease (PD) affects an estimated 7 to 10 million people worldwide, and only symptomatic treatments are presently available to relieve the consequences of brain dopaminergic neurons loss.
Nataša Z. Kuštrimović, C. Comi, L. Magistrelli, E. Rasini, M. Legnaro, R. Bombelli, I. Aleksic, F. Blandini, B. Minafra, G. Riboldazzi, Andrea Sturchio, M. Mauri, G. Bono, F. Marino, M. Cosentino   +14 more
semanticscholar   +1 more source

Investigation on Disaster Mechanism of Diversion Tunnel Induced by Gripper TBM in Hydrokarst Erosion Stratum and Engineering Measures

Buildings
In gripper tunnel boring machine (TBM) tunneling through complex geological formations, the safe and efficient recovery from large-scale collapses remains a formidable challenge.
Tengtian Yang
doaj   +1 more source

Single-cell RNA-seq and computational analysis using temporal mixture modelling resolves Th1/Tfh fate bifurcation in malaria

Science immunology, 2017
Computational modeling defines T helper cell differentiation toward multiple fates during experimental malaria. Fork in the road for immune cells Immune cell differentiation along T helper pathways can profoundly influence the nature of the immune ...
Stuti Mehta, D. Cronkite, M. Basavappa, Tahnee L. Saunders, Fatemeh Adiliaghdam, Hajera Amatullah, Sara A. Morrison, J. Pagan, R. Anthony, P. Tonnerre, G. Lauer, James C. Lee, Sreehaas Digumarthi, L. Pantano, Shannan J. Ho Sui, Fei Ji, Ruslan I Sadreyev, Chan Zhou, Alan C. Mullen, Vinod Kumar, Yang Li, C. Wijmenga, Ramnik J. Xavier, T. Means, Kate L. Jeffrey   +24 more
semanticscholar   +1 more source

Prediction of the Unconfined Compressive Strength of Salinized Frozen Soil Based on Machine Learning

Buildings
Unconfined compressive strength (UCS) is an important parameter of rock and soil mechanical behavior in foundation engineering design and construction.
Huiwei Zhao, Hui Bing
doaj   +1 more source