Results 141 to 150 of about 230,695 (309)

Detection of a novel 40 000 MW excretory Toxoplasma gondii antigen by murine Th1 clone which induces toxoplasmacidal activity when exposed to infected macrophages

, 1997
Gaby Reichmann, Stefan Stachelhaus, Roland Meisel, Marie-Noëlle Mévélec, Jean‐François Dubremetz, H. DLUGONSKA§, H. Fischer   +6 more
openalex   +2 more sources

Alloantigen-Reactive Th1 Development in IL-12-Deficient Mice [PDF]

, 1998
Joseph R. Piccotti, Kewang Li, Sherri Y. Chan, Jessica Ferrante, Jeanne Magram, E. J. Eichwald, D. Keith Bishop   +6 more
openalex   +1 more source

TIA1‐Mediated Stress Granules Promote the Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis through Upregulating IL‐31RA Signaling

Advanced Science, Volume 12, Issue 14, April 10, 2025.
In EAE mice, TIA1 is translocated from the nucleus to the cytoplasm, facilitating SGs formation in neurons. TIA1 knockout in the central nervous system (CNS) of EAE mice yields a notable diminution in neuronal SGs, mitigates CNS inflammatory infiltration, and curtails axonal demyelination.
Xin Hua, Lingting Jin, Zheyu Fang, Yiyun Weng, Yuan Zhang, Jingjing Zhang, Dewei Xie, Yang Tang, Siyu Guo, Yingying Huang, Yilin Dai, Jia Li, Zhihui Huang, Xu Zhang   +13 more
wiley   +1 more source

Switch of CD4+ T Cell Differentiation from Th2 to Th1 by Treatment with Cathepsin B Inhibitor in Experimental Leishmaniasis [PDF]

, 1998
Yoichi Maekawa, Kunisuke Himeno, Hiroyuki Ishikawa, Hajime Hisaeda, Tohru Sakai, Teruki Dainichi, Tetsuji Asao, Robert A. Good, Nobuhiko Katunuma   +8 more
openalex   +1 more source

ROS‐Responsive Microneedle Patches Enable Peri‐Lacrimal Gland Therapeutic Administration for Long‐Acting Therapy of Sjögren's Syndrome‐Related Dry Eye

Advanced Science, Volume 12, Issue 16, April 24, 2025.
A new strategy for constructing smart gel‐based MN patches is developed to overcome the insufficient drug delivery of eye drops to the lacrimal gland. The gel‐based MN patches achieved long‐acting drug release in a ROS‐responsive manner, and separable base in a temperature‐responsive manner.
Jingqing Mu, Xiangyu Ding, Yapeng Song, Baoyue Mi, Xiaolong Fang, Baihua Chen, Bin Yao, Xuguang Sun, Xiaoyong Yuan, Shutao Guo, Xia Hua   +10 more
wiley   +1 more source

Ethanol Feeding Impairs Innate Immunity and Alters the Expression of Th1‐ and Th2‐Phenotype Cytokines in Murine Klebsiella Pneumonia [PDF]

, 1998
David A. Zisman, Robert M. Strieter, Steven L. Kunkel, Wan C. Tsai, Jodi M. Wilkowski, Kathy A. Bucknell, Theodore J. Standiford   +6 more
openalex   +1 more source

Microbiota‐Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration

Advanced Science, EarlyView.
Lactobacillus johnsonii and its associated purine metabolite inosine not only restrict systemic B cell differentiation, but also contribute to immune cell infiltration in the kidneys, thereby serving dual functions in mitigating the progression of systemic lupus erythematosus (SLE).
Lingyu Gao, Yuhan Zhang, Zhi Hu, Shengwen Chen, Qiaolin Wang, Yong Zeng, Huiqi Yin, Junpeng Zhao, Yijing Zhan, Changxing Gao, Yue Xin, Bing Chen, Stijn van der Veen, Ming Zhao, Deyu Fang, Qianjin Lu   +15 more
wiley   +1 more source

Lung Injury Induced by Alloreactive Th1 Cells Is Characterized by Host-Derived Mononuclear Cell Inflammation and Activation of Alveolar Macrophages [PDF]

, 1998
Joan G. Clark, David K. Madtes, Robert C. Hackman, Wei Chen, Martin A. Cheever, Paul J. Martin   +5 more
openalex   +1 more source

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

Th1-associated immune responses to beta-galactosidase expressed by a replication-defective herpes simplex virus. [PDF]

, 1996
J O Brubaker, Claudette M. Thompson, Lynda A. Morrison, David M. Knipe, George R. Siber, Robert W. Finberg   +5 more
openalex   +1 more source