This study develops an integrated platform for real‐time, on‐the‐fly imaging of focused ultrasound‐induced cell ablation and responses at cellular and subcellular levels. It reveals that focused ultrasound could induce cellular mechanolysis through subcellular cavitation bubbles growing under confined contact with cells.
Ziyue Bai, Zaimeng Li, Yue Shao
wiley +1 more source
Primary Th1 Cell Immunization Against HIVgp160 in SCID-hu Mice Coengrafted with Peripheral Blood Lymphocytes and Skin [PDF]
Nadirah Delhem+7 more
openalex +1 more source
NETs‐CD44‐IL‐17A Feedback Loop Drives Th17‐Mediated Inflammation in Behçet's Uveitis
In experimental autoimmune uveitis (EAU), neutrophils interact with T helper 17 (Th17) cells through neutrophil extracellular traps (NETs) to exert a pro‐inflammatory effect. In vitro and in vivo experiments identify that NETs promote IL‐17A secretion in Th17 cells via CD44, and increasing IL‐17A further induces more NETs formation.
Yi Wu+11 more
wiley +1 more source
Regulatory B cells attenuate sepsis-associated pancreatic injury by regulating T cell homeostasis. [PDF]
Liu P, Xiao Z, Lu X, Zhang X, Huang J.
europepmc +1 more source
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. [PDF]
N.G. Jacobson+6 more
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This study presents an electret‐inspired charge‐injected self‐powered hydrogel (QOSP) for the treatment of second‐degree burn wounds infected with Staphylococcus aureus and Pseudomonas aeruginosa. The hydrogel effectively eliminates bacteria and enhances cell proliferation through electrical stimulation, thereby accelerating wound healing. Additionally,
Mujie Liu+29 more
wiley +1 more source
LFA-1/ICAM-1 Interactions Between CD8<sup>+</sup> and CD4<sup>+</sup> T Cells Promote CD4<sup>+</sup> Th1-Dominant Differentiation and CD8<sup>+</sup> T Cell Cytotoxicity for Strong Antitumor Immunity After Cryo-Thermal Therapy. [PDF]
Yao Y+6 more
europepmc +1 more source
High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni+15 more
wiley +1 more source
Antitumor CD4+ T Helper 1 Cells Target and Control the Outgrowth of Disseminated Cancer Cells. [PDF]
Ramamoorthi G+18 more
europepmc +1 more source
Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis [PDF]
Jonathan M. Spergel+4 more
openalex +1 more source