Results 161 to 170 of about 230,695 (309)

Unraveling the Microenvironment and the Pathogenic Axis of HIF‐1α–Visfatin–Fibrosis in Autoimmune Pancreatitis Using a Single‐Cell Atlas

Advanced Science, Volume 12, Issue 12, March 27, 2025.
Single‐cell RNA sequencing reveals that type 1 AIP exhibits increased amount and subtypes of B and plasma cells, particularly IgG4+ plasma cells, along with an expansion of Tfh and T helper CD4+ cells. Both AIP types share upregulation of HIF1A+ classical monocytes, which promote pancreatic fibrosis through increased visfatin production.
Deyu Zhang, Congjia Ma, Zhen Wang, Yanfang Liu, Zaoqu Liu, Wanshun Li, Yue Liu, Chang Wu, Liqi Sun, Fei Jiang, Hui Jiang, Xiaoju Su, Lisi Peng, Jiayu Li, Xinyue Wang, Hua Yin, Dongling Wan, Yuyan Zhou, Xiaorong Tian, Shiyu Li, Zhendong Jin, Baoan Ji, Zhaoshen Li, Haojie Huang   +23 more
wiley   +1 more source

Incidental Thoracic Th1 Spina Bifida Occulta Detection Following Sports Injury: A Case Report with Comprehensive Radiological Insights. [PDF]

J Orthop Case Rep
Kara S, Gorani A, Baillon B, Grandjean A, Waldburg TV, Lawson TM.   +5 more
europepmc   +1 more source

Perfis linfocitários Th1/Th2 e patogenia da co-infecção tuberculose/SIDA

, 1999
Margarida Marques, M. Fontes Baganha, Aníbal Pinto, L Vera, Leonardo Mesquita, Carlos Robalo Cordeiro, Rita Corte Real, Maria Filomena Botelho, Marli Rosa, Antonio Silvestre   +9 more
openalex   +1 more source

Multistage Regulation of Th1-Type Immune Responses by the Transcription Factor IRF-1 [PDF]

, 1997
Shinsuke Taki, Takeo Sato, Kouetsu Ogasawara, Taeko Fukuda, Mitsuharu Sato, Shigeaki Hida, Gen Suzuki, Masao Mitsuyama, Eun‐Hee Shin, Soumei Kojima, Tadatsugu Taniguchi, Yoshihiro Asano   +11 more
openalex   +1 more source

YC‐4‐3, a Novel Glycogen Synthase Kinase 3β Inhibitor, Alleviates the Endoplasmic Reticulum Stress of Macrophages in Primary Immune Thrombocytopenia

Advanced Science, Volume 12, Issue 17, May 8, 2025.
A patented GSK‐3β inhibitor (GSK‐3βi), new benzothiazepinone compounds (BTZs), YC‐4‐3, can modulate the inflammatory status of macrophages in primary immune thrombocytopenia (ITP), and improve the thrombocytopenia in murine ITP models by directly interacting with endoplasmic reticulum (ER) stress response.
Pengcheng Xu, Lili Ji, Yanxia Zhan, Yang Ou, Xia Shao, Xibing Zhuang, Fanli Hua, Feng Li, Hao Chen, Yong Chu, Yunfeng Cheng   +10 more
wiley   +1 more source

The synergistic effects of PM_2.5 and high-fat diet on Th1/Th2 balance in model mice with asthma. [PDF]

J Thorac Dis
Bai R, Liu B, Li T, Zhou H, Yue X, Liu Y, Shan Y, Li Z, Wei Y, Wu J.   +9 more
europepmc   +1 more source

Influência dos perfis Th1/Th2 no espectro de gravidade da Tuberculose Pulmonar**Trabalho de Inverstigaçã subsidiado pelo Projecto 57/95da comissão de Foment da Inverstigação do Ministério da Saude, do qual foi Coordenadora a Dra Maria Alcide Tavares Marques.

, 1998
M. Fontes Baganha, María Aldina Marques, Aníbal Pinto, L. Vera, L. Mesqujta, Cheryl Cordeiro, Cátia Isabel Viriato Alcobia, Maria Filomena Botelho, Marli Rosa   +8 more
openalex   +1 more source

Gluten specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or Th0 profile dominated by interferon gamma. [PDF]

, 1995
Ellen M Nilsen, Knut E.A. Lundin, Peter Krajči, Helge Scott, Ludvig M. Sollid, P Brandtzæg   +5 more
openalex   +1 more source

Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases

Advanced Science, Volume 12, Issue 13, April 3, 2025.
This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...
Shuna Hou, Jiachen Yu, Yongshuang Li, Duoyi Zhao, Zhiyu Zhang   +4 more
wiley   +1 more source

Th1 polarization in Bordetella pertussis vaccine responses is maintained through a positive feedback loop. [PDF]

Nat Commun
Willemsen L, Lee J, Shinde P, Soldevila F, Aoki M, Orfield S, Kojima M, da Silva Antunes R, Sette A, Peters B.   +9 more
europepmc   +1 more source