Results 121 to 130 of about 10,554,980 (260)

Vaccine-induced Th17 cells are established as resident memory cells in the lung and promote local IgA responses

Mucosal Immunology, 2016
The ability to mount accelerated and efficient mucosal immune responses is critically important to prevent the establishment of many infections. Secretion of immunoglobulin A (IgA) is a key component in this first line of defense, but the underlying ...
D. Christensen, R. Mortensen, I. Rosenkrands, J. Dietrich, P. Andersen   +4 more
semanticscholar   +1 more source

Inflammatory Th17 Cells Express Integrin αvβ3 for Pathogenic Function

Cell Reports, 2016
Interleukin-23 (IL-23) is required for inflammatory Th17 cell function in experimental autoimmune encephalomyelitis (EAE), and IL-23 blockade reduces the number of effector Th17 cells in the CNS.
Fang Du, Abhishek V. Garg, Karis Kosar, Saikat Majumder, David G. Kugler, Gerard Hernandez Mir, Maria Maggio, Matthew Henkel, Adam Lacy-Hulbert, Mandy J. McGeachy   +9 more
doaj   +1 more source

The cell cycle related rhythms, cells' states correlation and the cancer [PDF]

arXiv, 2015
We consider the decision making by mammalian cells, looking them as dynamic systems with rhythms. We calculate the effective dimension of the cell division model of the healthy mammalian cells consistent with the data: it is described via a four dimensional dynamic system. We assume that the cell's decision making property is strongly affected by the
arxiv  

Th17 cells play a critical role in the development of experimental Sjogren's syndrome [PDF]

, 2015
Objective Although Th17 cells have been increasingly recognised as an important effector in various autoimmune diseases, their function in the pathogenesis of Sjögren's syndrome (SS) remains largely uncharacterised.
Cao, X, Chan, VSF, Deng, J, Jiao, Z, Ko, KH, Lau, WCS, Lin, X, Lu, L, Rui, K, Tian, J, Wang, S, Wang, X   +11 more
core   +1 more source

Th17 Cells Pathways in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders: Pathophysiological and Therapeutic Implications

Mediators of Inflammation, 2016
Several animal and human studies have implicated CD4+ T helper 17 (Th17) cells and their downstream pathways in the pathogenesis of central nervous system (CNS) autoimmunity in multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD ...
G. Passos, D. Sato, J. Becker, K. Fujihara   +3 more
semanticscholar   +1 more source

Kirenol attenuates experimental autoimmune encephalomyelitis by inhibiting differentiation of Th1 and th17 cells and inducing apoptosis of effector T cells. [PDF]

, 2015
Experimental autoimmune encephalomyelitis (EAE), a model of multiple sclerosis (MS), is characterized by CNS demyelination mediated by autoreactive T cells.
Deng, Wenbin, Fan, Xiaohang, Liu, Wenwei, Xiao, Juan, Yang, Lin, Yang, Rongbing   +5 more
core   +2 more sources

Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties

Journal of Neuroinflammation, 2017
Autoreactive Th1 and Th17 cells are believed to mediate the pathology of multiple sclerosis in the central nervous system (CNS). Their interaction with microglia and astrocytes in the CNS is crucial for the regulation of the neuroinflammation. Previously,
C. K. Prajeeth, Julius Kronisch, Reza Khorooshi, B. Knier, Henrik Toft-hansen, V. Gudi, S. Floess, J. Huehn, T. Owens, T. Korn, M. Stangel   +10 more
semanticscholar   +1 more source

LncRNA H19 over-expression inhibited Th17 cell differentiation to relieve endometriosis through miR-342-3p/IER3 pathway

Cell & Bioscience, 2019
Objective To investigate the mechanism of LncRNA H19 in Th17 cell differentiation and endometrial stromal cells (ESCs) proliferation in endometriosis (EMS).
Zheying Liu, Liya Liu, Yun Zhong, Mingbo Cai, Junbi Gao, Chaoyue Tan, Xiaoxiao Han, Ruixia Guo, Liping Han   +8 more
doaj   +1 more source

Prostaglandin receptor EP4 expression by Th17 cells is associated with high disease activity in ankylosing spondylitis

Arthritis Research & Therapy, 2019
Background Th17 cells are involved in the pathogenesis of ankylosing spondylitis (AS). However, the mechanism underlying enhanced Th17 cell accumulation in AS remains unknown.
Charlotte Klasen, Anja Meyer, Paula S. Wittekind, Iris Waqué, Schafiq Nabhani, David M. Kofler   +5 more
doaj   +1 more source

Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties [PDF]

, 2006
Casey T. Weaver, Laurie E. Harrington, Paul R. Mangan, Maya Gavrieli, Kenneth M. Murphy   +4 more
openalex   +1 more source