Results 11 to 20 of about 12,148,459 (347)
Brain, Behavior, and Immunity, 2017 T helper 17 (Th17) cells have recently been implicated in depression, which adds to the list of several other diseases of the central nervous system (CNS) that are already known to involve Th17 cells.
Eléonore Beurel, J. Lowell
semanticscholar +5 more sources
Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity
Cell, 2021 Summary While intestinal Th17 cells are critical for maintaining tissue homeostasis, recent studies have implicated their roles in the development of extra-intestinal autoimmune diseases including multiple sclerosis.
Alexandra Schnell +2 more
exaly +2 more sources
Th17 Cells in Viral Infections—Friend or Foe?
Cells, 2021 Th17 cells are recognized as indispensable in inducing protective immunity against bacteria and fungi, as they promote the integrity of mucosal epithelial barriers.
Iury Amancio Paiva +3 more
doaj +2 more sources
Th17 Cells in Periodontitis and Its Regulation by A20
Frontiers in Immunology, 2021 Periodontitis is a prevalent chronic disease that results in loss of periodontal ligament and bone resorption. Triggered by pathogens and prolonged inflammation, periodontitis is modulated by the immune system, especially pro-inflammatory cells, such as ...
Ning Huang, Hao Dong, Yuqi Luo, Bin Shao
doaj +2 more sources
Molecular control of pathogenic Th17 cells in autoimmune diseases
International Immunopharmacology, 2020 IL-17A-producing CD4+ T helper cells (Th17) are crucial for the development of inflammatory and autoimmune diseases and thus are exploited for clinical immunotherapies.
Bing Wu, Yisong Y Wan
exaly +2 more sources
Th17 cells in human disease [PDF]
Immunological Reviews, 2008 Summary:Our understanding of the role of T cells in human disease is undergoing revision as a result of the discovery of T‐helper 17 (Th17) cells, a unique CD4+T‐cell subset characterized by production of interleukin‐17 (IL‐17). IL‐17 is a highly inflammatory cytokine with robust effects on stromal cells in many tissues.
Tesmer, Laura A. +3 more
openaire +4 more sources
Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation [PDF]
Nature, 2015 Inflammation is a beneficial host response to infection but can contribute to inflammatory disease if unregulated. The Th17 lineage of T helper (Th) cells can cause severe human inflammatory diseases.
N. Gagliani +22 more
semanticscholar +2 more sources
Frontiers in Immunology, 2019 Women have increased prevalence of Th17-mediated autoimmune diseases, including lupus and multiple sclerosis, and severe asthma. While estradiol and progesterone increased IL-17A production in Th17 cells by inhibiting Let7f miRNA expression and ...
Hubaida Fuseini +8 more
doaj +2 more sources
More stories on Th17 cells [PDF]
Cell Research, 2009 For more than two decades, immunologists have been using the so-called Th1/Th2 paradigm to explain most of the phenomena related to adaptive immunity. The Th1/Th2 paradigm implied the existence of two different, mutually regulated, CD4(+) T helper subsets: Th1 cells, driving cell-mediated immune responses involved in tissue damage and fighting ...
Alexandre S, Basso +2 more
openaire +3 more sources
Th17 cells in primary Sjögren's syndrome: Pathogenicity and plasticity
Journal of Autoimmunity, 2018 Th17 cells play an important physiological role at mucosal barriers, and are involved in inflammatory responses to pathogens. Th17 cells and their signature cytokine IL-17 are also present in salivary gland lesions of primary Sjögren's syndrome (pSS ...
Gwenny M Verstappen +2 more
exaly +2 more sources