Results 11 to 20 of about 127,043 (265)
Human Th17 cells: Are they different from murine Th17 cells? [PDF]
European Journal of Immunology, 2009 AbstractType 17 Th (Th17) cells have been identified as a distinct population of CD4+ effector T cells different from Th1 and Th2 cells. While the pre‐eminent cytokine of Th1 cells is IFN‐γ and that of Th2 cells is IL‐4, the distinctive cytokine of Th17 cells is IL‐17A.
ANNUNZIATO, FRANCESCO +4 more
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Th17 Cells in Viral Infections—Friend or Foe?
Cells, 2021 Th17 cells are recognized as indispensable in inducing protective immunity against bacteria and fungi, as they promote the integrity of mucosal epithelial barriers.
Iury Amancio Paiva +3 more
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Frontiers in Immunology, 2022 Multiple sclerosis (MS) is characterized by the loss of myelin and of myelin-producing oligodendrocytes (OLs) in the central nervous system (CNS). Pro-inflammatory CD4+ Th17 cells are considered pathogenic in MS and are harmful to OLs.
Hélène Jamann +28 more
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Arthritis Research & Therapy, 2008 The discovery in mice of a new lineage of CD4+ effector T helper (Th) cells that selectively produce IL-17 has provided exciting new insights into immune regulation, host defence, and the pathogenesis of autoimmune and other chronic inflammatory disorders.
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Preferential recruitment of Th17 cells to cervical cancer via CCR6-CCL20 pathway. [PDF]
PLoS ONE, 2015 Our previous studies suggest that Th17 cells accumulate within tumor tissues and correlate with recurrence of cervical cancer patients. However, the source of the increased tumor-infiltrating Th17 cells remains poorly understood.
Qing Yu, Xiang-ming Lou, Yan He
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The role of Th17 cells in endocrine organs: Involvement of the gut, adipose tissue, liver and bone
Frontiers in Immunology, 2023 T Helper 17 (Th17) cells are adaptive immune cells that play myriad roles in the body. Immune–endocrine interactions are vital in endocrine organs during pathological states.
Changyan Zi +3 more
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BBA Advances, 2023 Th17 cells are powerful inflammation promoters in the pathogenesis of abdominal aortic aneurysms (AAAs). Myeloid-derived suppressor cells (MDSCs) can promote the differentiation of Th17 cells in chronic inflammatory autoimmune injury.
Li Lu +6 more
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Purinergic Signaling as a Regulator of Th17 Cell Plasticity. [PDF]
PLoS ONE, 2016 T helper type 17 (Th17) lymphocytes, characterized by the production of interleukin-17 and other pro-inflammatory cytokines, are present in intestinal lamina propria and have been described as important players driving intestinal inflammation.
Dominique Fernández +17 more
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BMC Pulmonary Medicine, 2019 Background Th17 cells are believed to be important proinflammatory cells in the pathogenesis of chronic obstructive pulmonary disease (COPD). Recent evidence demonstrates that Th17 cells display substantial developmental plasticity, giving rise to Th17 ...
Weihan Xu, Ruimin Li, Yongchang Sun
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RORγt-Raftlin1 complex regulates the pathogenicity of Th17 cells and colonic inflammation
Nature Communications, 2023 Th17 cells that produce Interleukin IL-17 are pathogenic in many human diseases, including inflammatory bowel disease, but are, paradoxically, essential for maintaining the integrity of the intestinal barrier in a non-inflammatory state.
Amir Kumar Singh +13 more
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