Results 41 to 50 of about 4,870,412 (256)

Stimulation of Th17-cells.

open access: yes, 2021
Example of unstimulated Th17-cells (A) and stimulated Th17-cells (B) in canine peripheral blood sample of a dog suffering from intervertebral disc herniation measured by using flow cytometry.
Regina Carlson (388166)   +4 more
core   +1 more source

Dysregulation of Th17 cells during the early post-transplant period in patients under calcineurin inhibitor based immunosuppression. [PDF]

open access: yesPLoS ONE, 2012
Accumulating evidence suggests that Th17 cells play a role in the development of chronic allograft injury in transplantation of various organs. However, the influence of current immunosuppressants on Th17-associated immune responses has not been fully ...
Byung Ha Chung   +9 more
doaj   +1 more source

Alterations of the gut microbial community structure modulates the Th17 cells response in a rat model of asphyxial cardiac arrest

open access: yesBiochemistry and Biophysics Reports, 2023
Th17 cells triggered inflammation is a critical element in cerebral ischemic injury, and the gut microbiota intricately impacts T lymphocytes. Nevertheless, it remains unclear whether the gut microbiota involves in cardiac arrest/cardiopulmonary ...
Qin Yuan   +7 more
doaj   +1 more source

Impact of HIV infection on the frequency and phenotype of Th17 cells in the female genital tract [PDF]

open access: yes, 2010
Includes bibliographical references (leaves 85-103).T helper (Th) 17 cells have recently been implicated in regulating gut mucosal immunity during HIV infection by sustaining gut mucosal barrier integrity, although they do not respond to HIV directly ...
Salkinder, Amy Leia
core   +1 more source

Survival Proteins Encourage Human T Helper 17 Cells to Escape from Cell Death

open access: yesProceedings, 2018
IL-17 producing T helper 17 (Th17) cells are identified as a distinct subset of CD4+ T helper cells. They play a role in immune response. Abnormal regulation of Th17 cells can play a role in different type of pathologies such autoimmune diseases and ...
Tuğçe Çimen, Ayten Nalbant
doaj   +1 more source

The protective and pathogenic role of Th17 cell plasticity and function in the tumor microenvironment

open access: yesFrontiers in Immunology, 2023
At the turn of the century, researchers discovered a unique subtype of T helper cells that secretes IL-17 and defined it as Th17. The latest study found that Th17 cells play both positive and negative definitive roles in the regulation of antitumor ...
Yuanyuan Pan   +6 more
doaj   +1 more source

TLR4-RelA-miR-30a signal pathway regulates Th17 differentiation during experimental autoimmune encephalomyelitis development

open access: yesJournal of Neuroinflammation, 2019
Background Toll-like receptor 4 (TLR4) is well known for activating the innate immune system; however, it is also highly expressed in adaptive immune cells, such as CD4+ T-helper 17 (Th17) cells, which play a key role in multiple sclerosis (MS) pathology.
Xuebin Qu   +6 more
doaj   +1 more source

Mesenchymal stem cells repress Th17 molecular program through the PD-1 pathway. [PDF]

open access: yesPLoS ONE, 2012
MSC display potent suppressive properties initially described a decade ago. More recently, MSC suppressive activities on T-cell effector pathways have been investigated.
Patricia Luz-Crawford   +7 more
doaj   +1 more source

The Th17 Lineage: From Barrier Surfaces Homeostasis to Autoimmunity, Cancer, and HIV-1 Pathogenesis

open access: yesViruses, 2017
The T helper 17 (Th17) cells represent a subset of CD4+ T-cells with unique effector functions, developmental plasticity, and stem-cell features. Th17 cells bridge innate and adaptive immunity against fungal and bacterial infections at skin and mucosal ...
Vanessa Sue Wacleche   +3 more
doaj   +1 more source

Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue [PDF]

open access: yes, 2011
The upper respiratory tract mucosa is the location for commensal Streptococcus (S.) pneumoniae colonization and therefore represents a major site of contact between host and bacteria.
Mitchell, T.J.   +28 more
core   +1 more source

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