Results 31 to 40 of about 199,388 (309)

Alterations of the gut microbial community structure modulates the Th17 cells response in a rat model of asphyxial cardiac arrest

open access: yesBiochemistry and Biophysics Reports, 2023
Th17 cells triggered inflammation is a critical element in cerebral ischemic injury, and the gut microbiota intricately impacts T lymphocytes. Nevertheless, it remains unclear whether the gut microbiota involves in cardiac arrest/cardiopulmonary ...
Qin Yuan   +7 more
doaj   +1 more source

Survival Proteins Encourage Human T Helper 17 Cells to Escape from Cell Death

open access: yesProceedings, 2018
IL-17 producing T helper 17 (Th17) cells are identified as a distinct subset of CD4+ T helper cells. They play a role in immune response. Abnormal regulation of Th17 cells can play a role in different type of pathologies such autoimmune diseases and ...
Tuğçe Çimen, Ayten Nalbant
doaj   +1 more source

Dysregulation of Th17 cells during the early post-transplant period in patients under calcineurin inhibitor based immunosuppression. [PDF]

open access: yesPLoS ONE, 2012
Accumulating evidence suggests that Th17 cells play a role in the development of chronic allograft injury in transplantation of various organs. However, the influence of current immunosuppressants on Th17-associated immune responses has not been fully ...
Byung Ha Chung   +9 more
doaj   +1 more source

Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production [PDF]

open access: yes, 2017
IL-2 is a pleiotropic cytokine that promotes the differentiation of Th cell subsets, including Th1, Th2, and Th9 cells, but it impairs the development of Th17 and T follicular helper cells.
Cherukur, Yesesri   +8 more
core   +1 more source

Th17 cells in human disease [PDF]

open access: yesImmunological Reviews, 2008
Summary:Our understanding of the role of T cells in human disease is undergoing revision as a result of the discovery of T‐helper 17 (Th17) cells, a unique CD4+T‐cell subset characterized by production of interleukin‐17 (IL‐17). IL‐17 is a highly inflammatory cytokine with robust effects on stromal cells in many tissues.
Tesmer, Laura A.   +3 more
openaire   +3 more sources

The Th17 Lineage: From Barrier Surfaces Homeostasis to Autoimmunity, Cancer, and HIV-1 Pathogenesis

open access: yesViruses, 2017
The T helper 17 (Th17) cells represent a subset of CD4+ T-cells with unique effector functions, developmental plasticity, and stem-cell features. Th17 cells bridge innate and adaptive immunity against fungal and bacterial infections at skin and mucosal ...
Vanessa Sue Wacleche   +3 more
doaj   +1 more source

Retinoic acid as a modulator of T cell immunity [PDF]

open access: yes, 2016
Indexación: Scopus. DOAJ.Vitamin A, a generic designation for an array of organic molecules that includes retinal, retinol and retinoic acid, is an essential nutrient needed in a wide array of aspects including the proper functioning of the visual system,
Bono, M.R.   +5 more
core   +1 more source

Th17 and non-Th17 interleukin-17-expressing cells in chronic lymphocytic leukemia: delineation, distribution, and clinical relevance

open access: yesHaematologica, 2012
Background The levels and clinical relevance of Th17 cells and other interleukin-17-producing cells have not been analyzed in chronic lymphocytic leukemia.
Preetesh Jain   +15 more
doaj   +1 more source

Mesenchymal stem cells repress Th17 molecular program through the PD-1 pathway. [PDF]

open access: yesPLoS ONE, 2012
MSC display potent suppressive properties initially described a decade ago. More recently, MSC suppressive activities on T-cell effector pathways have been investigated.
Patricia Luz-Crawford   +7 more
doaj   +1 more source

The role of the novel Th17 cytokine IL-26 in intestinal inflammation [PDF]

open access: yes, 2008
Background and aims: Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in human disease is completely unknown. The aim of this study was to analyse its
Auernhammer, Christoph J.   +7 more
core   +1 more source

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